<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15296

Description Uncharacterized protein
SequenceMSLQQFQQEADKVDQALEAIHKKAIEAKKTIEELILMLNREDKVHWPDMLEKYSSLAALMSQLQIALRRNALPSGEENSGQLLRSNVFVPLRLQLEPDPRLEEMTQGRVVAWHHDVVPDYLRTKLNPEIETEEAYIENERNSKGQDYIIKQVVNLNKHVDLLLTNFATYDRAQTDTAIEKPAYSDAETQRLVRAIMCGEDLRQVRAPSAMLPQQLGAGTAVQPQPGQMGMAPGMAARGTGPGSVAMPQNRPQTPVTSTCQNSDSLTESVNLNLALRIQKRRTSQMLCHNPKLQSVIDKINGTSMKFHNPALKSLVSESGELFNELILRPDDPGSDHMLIAFPWFVAPIRCSFSNMTLRFVKEKLFENLRRMARKPFSWDPRDYIFYANQWQYDRWMWFYNEDMTISETGISTNMPMMLLKNPADLEAERNLEKSIGRAIGYPLEKLETTLNESLKAFRAELFTHVDKTVKERGNDGREHYAFPEENILDFETKDFCPHSLVQKIDKTHLIYRIYYRSEEDERNNIDDENKMKCMDVKFKQDYTPVSLIQTALHKLLSNKMITKEEADDAYLLQLVGKKSFLTSEKHKIVTYESVRSSFENYRHPKFILRRQSILYKDYRPPKPMHTPYYVHAHKDYLARERNLAAKHALGQPQSTMDSDANLPPNTLSLWEIDDNLHMKPISCSNVIGGMESDLQMYVRFSVYCGKALVAKKESNSTPKCKPSWSEHPFINLDLYLSDMPSLAVLNVQLMESKTKKGKKEETCIGWVNLCLRNWDDSLLQGRFTLFLRSGPVEFPPNGPICHNEKKGDATNPVSRLIIELPHYGRKIYFPSMSLYRKFVAGSQNGQMAHLQRPPKYKPNDPNPPSNHHELVKLREIYNKVKLGTKLSNTDEELVFDWRYYVQKHIPELILVLVECDLMWKLRDHFAHFYIMLEDWPKLSLGTMLTLLNKRYLDVHVRQLAVRHLDAHLDHRSFPLFLLPLVQAIKCEPWPNSELVNLLLKKALMDYRIGHKLFWLMRAELANQMEDNRLTNLFKRLAIFIEAYLRGNEDHISTVVKQVEMLNKLTELSVYVKNYKEKDTATKKFQQKLQECHEKLENMESPLDPTHLLGPLRIEKCRVLGSAKMPLKLYWRNTNPLSAHYLPTYEIIFKNGDDLRQDMLVIQVLEVMDSIWKVHQIDCCLSTYPILPMGSNVGLIGCVSNCATIFEIQSEGGKMGTAVKSLDTKFLNQYLREHSKDNAKEYMEAADRFNMSCVGYSVATFIMGIKDRHNDNIMLTKDGKLFHIDFGHILGHGKTKLGIQRDRVPFVLTEHFLTVISKGNDVSMSKHEISKFKEQCIKAYIVLWRERHQFVSLFSLMYTMGLPEFSCEEDLEHLKKTIGMKLLTEEEAKKYFMSVFEEAFNGSWATKTNWFFHTVKHL
Length1417
PositionHead
OrganismDiploscapter pachys
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
Aromaticity0.09
Grand average of hydropathy-0.456
Instability index48.24
Isoelectric point8.18
Molecular weight164059.32
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
kinase activity	GO:0016301	IEA:UniProtKB-UniRule
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
phosphatidylinositol phosphorylation	GO:0046854	IEA:InterPro
phosphatidylinositol-mediated signaling	GO:0048015	IEA:UniProtKB-UniRule
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15296
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.59|      30|     245|     619|     659|       1
---------------------------------------------------------------------------
  619-  633 (-5.37/ 9.24)	............................RppkpmhtpYYVHAH
  637-  659 (31.80/13.63)	LARERNLAAKHALGQPQSTMDSD....................
  870-  904 (45.16/17.50)	LVKLREIYNKVKLGTKLSNTDEElvfdwR........YYVQKH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.92|      29|     244|     909|     947|       2
---------------------------------------------------------------------------
  909-  940 (47.98/53.04)	ILVLVECDLMwklRDHFAHFYIML......EDWPKLSL
  960-  994 (46.94/25.30)	AVRHLDAHLD...HRSFPLFLLPLvqaikcEPWPNSEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.37|      57|     245|      33|      90|       3
---------------------------------------------------------------------------
   33-   90 (90.96/52.71)	ELILMLnREDKVHWPDMLEKYSSLAALMSQLQ...IALRRNALPSGEENSGQLLRSNVFVP
  270-  329 (90.42/48.54)	NLNLAL.RIQKRRTSQMLCHNPKLQSVIDKINgtsMKFHNPALKSLVSESGELFNELILRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.60|      27|     245|     747|     788|       6
---------------------------------------------------------------------------
  711-  737 (49.34/46.55)	KKESNS...TPKCKPSWSEHPFI.NLDLYLS
  758-  788 (38.26/35.99)	KKEETCigwVNLCLRNWDDSLLQgRFTLFLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.83|      23|     271|     839|     868|       8
---------------------------------------------------------------------------
  839-  868 (37.33/38.98)	VAGSqnGQMahlqrPPKYKPNDPNPPSNHH
 1118- 1140 (44.50/26.22)	VLGS..AKM.....PLKLYWRNTNPLSAHY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.45|      13|      32|      91|     103|       9
---------------------------------------------------------------------------
   91-  103 (23.13/15.86)	LRLQLEPDPRLEE
  121-  133 (22.32/15.00)	LRTKLNPEIETEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.55|      18|      32|    1023|    1043|      10
---------------------------------------------------------------------------
 1023- 1043 (24.82/23.15)	QMEdnrLTNLFKRLAIFIEAY
 1057- 1074 (29.73/17.96)	QVE...MLNKLTELSVYVKNY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15296 with Med8 domain of Kingdom Metazoa
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