<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15290

Description Uncharacterized protein
SequenceMSLQQFQQEADKVDQALEAIHKKAIEAKKTIEELILMLNREDKVHWPDMLEKYSSLAALMSQLQIALRRNALPSGEENSGQLLRSNVFVPLRLQLEPDPRLEEMTQGRVVAWHHDVVPDYLRTKLNPEIETEEAYIENERNSKGQDYIIKQVANLNKHVDLLLTNFATYDRAQTDTAIEKPAYSDAETQRLVRAIMCGEDLRQVRAPSAMPPQQLGAGTVQPQSGQMGMAPGMTARGTGPGNVAMPQNRPQTPVTSTCQNSDSLTESVNLNLALRIQNLSLSRSSRGGSSRADFVGVEPRNYPGYSPTKERRTSQMLCHNPKLQSVIDKINGASMKFHNPAWKSLVSESGELFNELILRPDDPGSDHMLIAFPWFVAPIRCSFSNMTLRFVKEKLFENLRRMARKPFSWDPRDYIFYASQWQYDRWMWFYNEDMTISETGISTNMPMMLLKNPADLEAERNLEKSIGRAIGYPLEKLETTLNESLKAFRAELFTHVDKTVKERGNDGREHYAFPEENILDFETKDFCPHSLVQKIDKTHLIYRIYYRSEEDERNNIDDENKMKYMDVKFKQDYTPVSLIQTALHKFLSNKMITKEEADDAYLLQLVGKKSFLTSEKHKIVTYESVRSSFENYRNPKFILRRQSILYKDYRPPKPMHTPYYVHAHKDYLARERNLAAKHALGQPQSTMDSDANLPPNTLSLWEIDDNLHMKPISCSNVIGGMESDLQMYVRFSVYCGKALVAKKESNSTPKCKPSWSEHPFINLDLYLSDMPSLAVLNVQLMESKTKKGKKEETCIGWVNLCLRNWDDSLLQGRFTLFLRSGPVEFPPNGPIGHNEKKGDATNPVSRLIIELPHYGRKIYFPSMSLYRKFVAGSQNGQMAHLQRPPKYKPNDPNPPSNHHELIRLREIYNKVKLGTKLSNTDEELVFDWRYYVQKHIPELILVLVECDLMWKLRDHFAHFYIMLEDWPKLSLGTMLTLLNKRYLDVHVRQLAVRHLDAHLDHRSFPLFLLPLVQAIKCEPWPNSELVNLLLKKALMDYRIGHKLFWLMRAELANQMEDNRLTNLFKRLAIFIEAYLRGNEDHIATVVKQVEMLNKLTELSVYVKNYKEKDTATKKFQQKLQECHEKLESMESPLDPTHLLGPLRIEKCRVLGSAKMPLKLYWRNTNPLSAHYLPTYEIIFKNGDDLRQDMLVIQVLEVMDSIWKVHQIDCCLSTYPILPMGSNVGLIGCVSNCATIFEIQSEGGKMGTAVKSLDTKFLNQYLREHSKDNAKEYMEAADRFNMSCVGYSVATFIMGIKDRHNDNIMLTKDGKLFHIDFGHILGHGKTKLGIQRDRVPFVLTEHFLTVISKGNDVSMSKHEINKFKEQCIKAYIVLWRERHQFVSLFSLMYTMGLPEFSCEEDLEHLKKTIGMKLLTEEEAKKYFMSVFEEAFNGSWATKTNWFFHTVKHL
Length1448
PositionHead
OrganismDiploscapter pachys
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
Aromaticity0.09
Grand average of hydropathy-0.480
Instability index49.31
Isoelectric point8.27
Molecular weight167483.75
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
kinase activity	GO:0016301	IEA:UniProtKB-UniRule
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
phosphatidylinositol phosphorylation	GO:0046854	IEA:InterPro
phosphatidylinositol-mediated signaling	GO:0048015	IEA:UniProtKB-UniRule
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15290
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.46|      23|      32|    1049|    1074|       2
---------------------------------------------------------------------------
 1049- 1074 (31.90/27.62)	AELANQMEdnrLTNLFKRLAIFIEAY
 1083- 1105 (36.57/22.45)	ATVVKQVE...MLNKLTELSVYVKNY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.45|      13|      32|      91|     103|       3
---------------------------------------------------------------------------
   91-  103 (23.13/13.22)	LRLQLEPDPRLEE
  121-  133 (22.32/12.49)	LRTKLNPEIETEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.32|      17|      31|     340|     359|       4
---------------------------------------------------------------------------
  340-  359 (21.27/23.94)	PaWksLVSESGELFNELILR
  373-  389 (34.04/22.91)	P.W..FVAPIRCSFSNMTLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.18|      25|     271|     870|     899|       7
---------------------------------------------------------------------------
  828-  846 (30.10/ 9.67)	NGPIGHNEK....KGDATNPVSR..
  875-  899 (51.18/35.13)	NGQMAHLQRPPKYKPNDPNPPSNHH
 1156- 1171 (23.91/ 8.11)	.........PLKLYWRNTNPLSAHY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.16|      29|      46|     524|     552|      13
---------------------------------------------------------------------------
  524-  552 (51.60/35.84)	KDFCPHSLVQKIDKTHLIYRIYYRSEEDE
  571-  599 (46.56/31.57)	QDYTPVSLIQTALHKFLSNKMITKEEADD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.76|      15|      15|     635|     649|      16
---------------------------------------------------------------------------
  635-  649 (26.70/15.02)	PKFILRRQSI.LYKDY
  652-  667 (26.07/14.50)	PKPMHTPYYVhAHKDY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.94|      14|      22|     206|     220|      17
---------------------------------------------------------------------------
  206-  220 (22.61/18.78)	APsAMPPQQLGAGTV
  230-  243 (27.33/17.56)	AP.GMTARGTGPGNV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15290 with Med8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGSSRADFVGVEPRNYPGYSPTKERRTSQMLC
2) RQVRAPSAMPPQQLGAGTVQPQSGQMGMAPGMTARGTGPGNVAMPQNRPQTPVTSTCQNSD
287
202
318
262










Molecular Recognition Features






MoRF SequenceStartStop




NANANA