<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15288
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MNQSTNNLTATQAIAPYPNPPEYAQFYTNERLAQGDVPQPPPPFTEFRVFGEEYKLDDDVIRPLESAGIRQLYPAKYDWKEEMKKLNRSVIAAFLDLLDILIRCPDHSEREVKLTDIHTLFINMHHLINEYRPVQARDLIRLMQVDQIKELEEAVELFKTYMDDGRKALKEVMKVDTSRLTQPPKPKPSTLVTIDSDEEETSMPRTKPAQEDVEMLDDDSPASSVGQTHRRGAKPSLELAKHRHAIDLEFFNQL |
Length | 254 |
Position | Middle |
Organism | Diploscapter pachys |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida>
Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.683 |
Instability index | 46.19 |
Isoelectric point | 5.11 |
Molecular weight | 29315.88 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP15288
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 67.70| 20| 28| 127| 146| 1
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127- 146 (33.87/22.06) LINEYRPVQARDLIRLMQVD
157- 176 (33.83/22.02) LFKTYMDDGRKALKEVMKVD
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 126.77| 39| 157| 56| 98| 2
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56- 98 (58.69/45.83) LDDDviRPLESAGIRQLYPAKYDWkeEMKKLNRSVIAAFLDLL
216- 254 (68.09/41.29) LDDD..SPASSVGQTHRRGAKPSL..ELAKHRHAIDLEFFNQL
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