<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP15270

Description Uncharacterized protein
SequenceMAHRMLYQALCKVGDRVVYPALPAFAKPAWNHPAGPKTVFFWAPTIKWCLIGAGLADLARPADKLSASQNTALAGTGFIWTRYCLVITPINYYLSSVNFFVGCIGLTQLIRVAYYRRMEENGSCDLTCIASIVVVGLMWGATNPFLRMASASTSNADKNRDAKQSATSVCSRVASFIGSFILLLLDWRFSLPFALNQLASIVFQILVVYLPVSLVVPCVNAIQVASSAATSQLLGESRPSMQTAVGCLLVTFGVFIMMSCKTCDDKTRALTIIPKHLTWPLHPQICLLPANQAREQPNASSSEREQSIQQSLSQLSQQQHSGGTSASASLSNSAYESKTGIMRFRQAVINYVENNTLKYFFPNDIDRSTDVLGVLATVLLHNMEDPERDVIVEALVSLVTDYKDPSDPMQKTKRSTYEKVIDEILRYAYSEGALGLNRTVHGLILTSDFSLYTPLNLEKWRFIEECIPKLDYKGIQILIRTILINQFKDVPLVLSSEQMRQLTPIENMLLRLLDRENNALPAIFSMTEASRGSIVRSANIFPRLTATLSHLNAMFRPIADLTYVVGRPFMFPLPGHPAFLAAAPAWKMESDCNKISHKPAYLPYRPELKQPQVYTLYMLLKQPRGKEYLSNIIRQVSPHSLHTSPWEPLLSVFVCDVMCEAERLPENAEIPRYQWENLLSIFLHFVQIQHITISHIFKVLSSILEKTTYRRARDEVMWLALQLIGSFPALLNKETITEAARLYNVLFNEEVVWTGASDHPLKLTRFLAAACMWNILDGTDGLPQASSSLQVQVDFIRSKVDTADSEQALLAVLANAYRSDSNVYKNVKQAFAFWLIGPPNEELHFISYNRTVINKFAPIQTQYLDSLTMRAKNHVYIVCTSALQKSSFQLSRLPSPALIDTMARLVQTMEFDFSAKSFITLVVRTLQGAVCHQPLEGARESCYIFYEILCYRIPNIAIPVHARLYHIIMQTITAMITLPYTMPVEYMQQNIPPGSQSFSTCSLSAFHLYSVFEQTLIRQWAWTSHADLLYCAISFFHRQCATGIISLHFYFPPGKQLKPELMPYGPEEFKRASHIGLLLINPNYYSQTQEQQNNVVPPSAEISRMFFISLLRAMKIMGVETTPDCELFTAINQAYKWPASQFLSFPPEVYKLAQPESEEKIRDDEMKIKETVNRDFLAWQGMHTPTFMDYMLEPLKQGRSPLTIFCIVHQVLCEDIRRGSDIRNVVYSILEMYQPKHIQMATNALVEYVIALMNTSTNKTEEDLIIRVLMQLVFEWQLLPFDRLLNSLVLHPVTDRQSQLALAIVSAFCSDQCEPLTNRLNFYLQNVPPRRDNNQGEFFRRLAEYHHNFPELTYSEMRRRIEEPNLIDSNVHMPIYYGSLVERLLPIIDYTLARALELGTNDAFFVPIMSTFSKLYRYHPSPIQFVYTILFTLHEHIGNQERARNLTMHILAPSKSWSEESLLTQSFIAYNHQRSSHEQVIADLVDRLIQSSEFLTAPPAFCAQDWRFAEFPPATQTLYLACIELMASPYKPEIMVPAMINYLYGRRHKRPYSVLNAMALILTALPAIYGKVLQEEFLAAIDSEQLEDLRFEDIVLDNFEENMLLNMPNRAMIISVMLQAFWQHSHMVSISKYAGEYVTEIFKKVTTENGLWYVLRLAMPLLQRCQDTRDRHKQIFDIFNVARQLMNKLAELSEAGVEFVHQNEICDLLYHLKYTFIGDFLRRDAEASFSRLNPKMRERLKFFTSLQSSSSSSTAGSKHHDEDIVSKLSTSVRPEGVLSASVSAVGGVSSSSHLGSLSRTASDAGTVGMQSMQGMGMSSSNSSLMDMQLQSQTITSAQQHQALSSRNSGFINESMNGECVEPIAGCSNDLSNSDVKQCPWYWGDIKWKDAERLLLLCSNGTFLLRDSHSDRFLFTVSYKINEKVYHSRIRLNDGFVNVKGTNCAVRLLEQEIEKSRSGERHMLMHKRGAEAEASEVQLTQPLSRLQLLPSLQYLCRLHIRLHFHPVKQMPAALQRLSPKLRTYVSDSKFIIPDLNYCYEILKSHSFPSAMTTIFALSSGALPSAIAVFRVSGNRSLPILQQITRRAKWEPRRLQFVEIIDNRPAAAIAGNRQTSSLIDRAMAVYLPGPATFTGEDTAEIYIHGSRAVASALADRLSAIEDVRHAKRGEFSKRAFFNGKMDLHEVQGLQNLINAETQRQRIVAYSQMRGGHKAVQIRDELADLIGRTFVLMDFGEHVESRIEDVRKDIHPLVVKTEQLLQLARGAEIVHRGLRVVLCGRPNSGKSSLLNALANRSIAIVSELAGTTRDIVETRLEVAGIPVAFTDTAGIWQCDNVVEKEGIRRAKQKLTEADLILLVVEPEMSFAQLDELVDEIQENANEAAPWVLVQNKADLMNDRCNEIAAFEHRRIRNRVQTCALTSEGVGELSRTLESWIGELCPNEQQECLADHALLSCALDELVLAAEATDPAIMCDHLQAAMEAYAEMVGGRVTEQILDNIFSKLCIGK
Length2505
PositionTail
OrganismDiploscapter pachys
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Diploscapter.
Aromaticity0.09
Grand average of hydropathy-0.075
Instability index49.02
Isoelectric point6.59
Molecular weight283321.13
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mitochondrial inner membrane	GO:0005743	IEA:InterPro
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GTP binding	GO:0005525	IEA:UniProtKB-KW
GTPase activity	GO:0003924	IEA:InterPro

GO - Biological Process
mitochondrial pyruvate transmembrane transport	GO:0006850	IEA:InterPro
tRNA modification	GO:0006400	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP15270
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.96|      12|      22|     576|     587|       1
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  576-  587 (24.35/14.36)	H.PAFLAAAPAWK
  597-  609 (20.61/10.82)	HkPAYLPYRPELK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     242.66|      76|     572|     867|     986|       2
---------------------------------------------------------------------------
  900-  986 (118.00/141.49)	DTMARLVQTMEFDFSAKSFITLVVRTLQGAVCHQPLEGAresCyifYEILC..YRiPNIAIPV.........HARLYHIImqtiTAMITLPYTMPVEY
 1483- 1569 (124.66/65.02)	DLVDRLIQSSEFLTAPPAFCAQDWRFAEFPPATQTLYLA...C...IELMAspYK.PEIMVPAminylygrrHKRPYSVL....NAMALILTALPAIY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.64|      22|      25|    1813|    1834|       3
---------------------------------------------------------------------------
 1787- 1807 (25.97/14.29)	.GVSSSSHLGSLSRTASDAGTV
 1813- 1834 (36.40/23.45)	QGMGMSSSNSSLMDMQLQSQTI
 1839- 1860 (35.27/22.46)	QHQALSSRNSGFINESMNGECV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     478.64|     130|     572|    1617|    1767|       4
---------------------------------------------------------------------------
 1617- 1749 (206.24/147.87)	MLQAFWQHSHMVSISKY.AGEYVTEIFKKVTTENGLWYVL.RLAMPLL.QRCQDTRD.RHKQIFDIFNVARQLMNKLAELSEAGVEFVHQN...EICDLLYHLKYTFIGDFLRRDAeASFSRLNPKMRERLKffTSLQSS
 2190- 2316 (172.87/111.47)	LINAETQRQRIVAYSQMrGGHKAVQIRDELADLIGRTFVLmDFGEHVE.SRIEDVR....KDIHPLVVKTEQLL.QLAR....GAEIVHRGlrvVLCGRPNSGKSSLLNALANRSI.AIVSELAGTTRDIVE..TRLEVA
 2352- 2437 (99.53/80.75)	LILLVVEPE..MSFAQL..DELVDEI.QENANEAAPWVLV.QNKADLMnDRCNEIAAfEHRRIRNRVQTCALTSEGVGELSRTLESWI..G...ELC...........................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.24|      30|      32|    1047|    1078|       5
---------------------------------------------------------------------------
 1047- 1078 (50.48/36.18)	LH.FYFPPGKQLKPELMPygP.EEFKRASHIGLL
 1080- 1111 (43.76/24.24)	INpNYYSQTQEQQNNVVP..PsAEISRMFFISLL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.04|      17|      21|    1311|    1328|       6
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 1311- 1328 (28.11/22.91)	DQCEpLTNRLNFYLQNVP
 1334- 1350 (33.93/21.83)	NQGE.FFRRLAEYHHNFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     304.08|     102|     191|     234|     349|       7
---------------------------------------------------------------------------
  234-  349 (150.34/114.71)	LGESRpsmqTAVGCLLVT.FGVFIMMSCktcdDKTRAL.TIIPKHLTWPLHPQICLLPANQAREQPNASSSE..REQS.IQQSLSQLSQQQHSgGTSASASLSNSayeSKTGIMrfRQAVI
  434-  540 (153.74/84.22)	LGLNR....TVHGLILTSdFSLYTPLNL....EKWRFIeECIPKLDYKGIQILIRTILINQFKDVPLVLSSEqmRQLTpIENMLLRLLDRENN.ALPAIFSMTEA...SRGSIV..RSANI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.68|      20|     572|     617|     636|       8
---------------------------------------------------------------------------
  617-  636 (37.06/23.30)	YML..LKQPRGKEYLSNIIRQV
 1190- 1211 (33.62/20.42)	YMLepLKQGRSPLTIFCIVHQV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     180.62|      54|     668|    1407|    1460|       9
---------------------------------------------------------------------------
 1407- 1460 (96.79/60.51)	PIMSTFSKLYRYHPSPIQFVYTILFTLHEHI.GNQERA....RNLTMHILAPSKSWSEE
 2077- 2135 (83.83/51.34)	PILQQITRRAKWEPRRLQFVEIIDNRPAAAIaGNRQTSslidRAMAVYLPGPATFTGED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.07|      47|    1047|     821|     876|      10
---------------------------------------------------------------------------
  822-  875 (67.66/73.48)	NVYKNVKQAFAfWligPPNEelhFISYNRTVINKFAPIQTQYLDSLTMRAKNHV
 1126- 1172 (80.41/50.00)	ELFTAINQAYK.W...PASQ...FLSFPPEVYKLAQPESEEKIRDDEMKIKETV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP15270 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QPNASSSEREQSIQQSLSQLSQQQHSGGTSASAS
296
329










Molecular Recognition Features






MoRF SequenceStartStop




NANANA