<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14911

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMWTNIFKIGELQTVSWFQFLPIEPDYSATSDRSSKAEQKDALNNTVLSAYLRLQSEGLLSTWTNSFVGPWDPSQGEHNPDEKIKLWLFLSGRHSSVPEMTQPAVAKLRVVSSDLWVAPGNSEEVAAALCQALRNSLERALRGLSYARFGDVFTKYNPPTRNQNSFRRAQPTVEFVFAATEEAIFVHVIISARYMRNLSSDDIEKVLTHTPRSVGEGLPGTVAPSGMLGRLVGCCPSDLARQVYSSKLSAPNLPGFTQPTICQLRGQSYYVEVALGFPPASTDKISESENNQIKKEFDSGKDPHLGDDGQQKLESADGLPVLERTFIYPPEAVMVPMVHQAFVRFSSKRMWSQDWMSSSSWEAWPFWNFSPSSYFRNSSFFGSSRGLGVNSNFLRLRRQRNNNSNGMASSISSVSSTSNGSEHAVAAKGGDLLADADSTACHQSDLPLNNDIAGSKMVSKRSRSEITEVSSHAGNEVRENMQGTNGQGGCSWGWGEEGVVMDINILLSEFGDFSDFFQEDELDFGEPPGTAESHALVTPASEFGDMPFIDSPSIAMDIPEQRLSPVGFTSMEAFNHETMSPIQDVASKVQEPLKEIASPAGSQSLVLSSSRSDFLTRAEATLTFAPEYAAVEISSCETPATLFTNPYLPGSKKRGSCGFSSRVYSYDVTQSSKVESAGDKSEKSDKLTPANLSRDVGRSSLYTLVQGRKNESEKSLNNADEQSCKGETSRPVSGETSFSSSLTIQKKSDSMLNVGYFLLSMKTALATEIECITFQAAMCRIRHTLVSLRTKASAELKSALSSAMQTESSSNSGLVPKYEMKRKETIPARLSSDVDHDMYDRSLLENVGVWRSVVVPKGAKPLDSLSAKTFTGTSPSVQRQPIVELLSAMALLVQQSTSFVDIALDIDDGDGSFFWLSLDEQRRRGFSCDPSMVHAGCGGLLGTCHSKDCAGVDLVDPLSAEVKIWCSVFFCHLYLSMHLFSMSFSGYRFQNHP
Length992
PositionKinase
OrganismHordeum vulgare subsp. vulgare (Domesticated barley)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Hordeinae> Hordeum.
Aromaticity0.09
Grand average of hydropathy-0.333
Instability index54.63
Isoelectric point5.39
Molecular weight108684.54
Publications
PubMed=23075845

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14911
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.90|      25|      28|     750|     777|       1
---------------------------------------------------------------------------
  752-  777 (37.62/40.67)	NVGYFLLSMKTALATEIECiTFQAAM
  779-  803 (38.28/26.23)	RIRHTLVSLRTKASAELKS.ALSSAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.82|      33|     135|     668|     701|       2
---------------------------------------------------------------------------
  668-  700 (51.59/32.84)	TQSSKVESAGDKSEKSDKLTPANLSRDV.GRSSL
  704-  737 (50.23/26.39)	VQGRKNESEKSLNNADEQSCKGETSRPVsGETSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.96|      22|      30|     493|     521|       4
---------------------------------------------------------------------------
  493-  515 (37.49/34.11)	WGEEGVVMDINILL...SEFGDFsDF
  523-  547 (37.48/16.32)	FGEPPGTAESHALVtpaSEFGDM.PF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     307.46|     117|     636|     189|     308|       5
---------------------------------------------------------------------------
   97-  252 (169.79/89.95)	PEMTQPAVAKLRVVSSDLWVAPGNSEEVAAALCQALRNSLERALRGLSYARFGDvftkyNP.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ptrnqnsfrraqptvefvfaateeaifvhviISARYMRNLSSDDIEKVLTHTP...RSVgeGLPGTVAPSGMLG..RLVGCCPSdLARQVYSSKLSAPNL
  253-  308 (70.57/29.75)	PGFTQPTICQLRGQSYYVEVALGFPPASTDKISESENNQIKKEFDSGKDPHLGD.....DG.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
  825-  890 (67.10/28.58)	.............................................................qqklesadglpvlertfiyppeavmvpmvhqafvrfsskrmwsqdwmssssweawpfwnfspssyfrnssffgssrglgvnsnflrlrrqrnnnsngmassissvsstsngsehavaakggdlladadstachqsdlplnndiagskmvskrsrseitevsshagnevrenmqgtngqggcswgwgeegvvmdinillsefgdfsdffqedeldfgeppgtaeshalvtpasefgdmpfidspsiamdipeqrlspvgftsmeafnhetmspiqdvaskvqeplkeiaspagsqslvlsssrsdfltraeatltfapeyaaveisscetpatlftnpylpgskkrgscgfssrvysydvtqsskvesagdkseksdkltpanlsrdvgrsslytlvqgrknesekslnnadeqsckgetsrpvsgetsfsssltiqkksdsmlnvgyfllsmktalateiecitfqaamcrirhtlvslrtkasaelksalssamqtesssnsglvpkyemkrketIPARLSSDVDHDMYDRSLLENVgvwRSV..VVPKGAKPLDSLSakTFTGTSPS.VQRQPIVELLSAMAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.98|      28|     507|     424|     451|       8
---------------------------------------------------------------------------
  424-  451 (49.79/33.01)	VAAKGGDLLADADSTACHQSDL..PLNNDI
  932-  961 (48.19/31.70)	VHAGCGGLLGTCHSKDCAGVDLvdPLSAEV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14911 with Med13 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KISESENNQIKKEFDSGKDPHLGDDGQQKLE
2) RSEITEVSSHAGNEVRENMQGTNGQGGCSW
283
462
313
491










Molecular Recognition Features






MoRF SequenceStartStop




NANANA