<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14882

Description ATP-dependent DNA helicase
SequenceQHLGVLKQKFPETPVLALTATATASVKEDVVQALGLANCVVFKQSFNRPNLRYFVMPKTKKCLEDIDRFIRENHHKECGIIYCLSRMDCEKVAEKLREYGHQASHYHGNMEPFDRTQVQRLWSMDKINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCVLYYNYSDYIRVKHMITQGSAEQVRSSSSSSHGQALATHKENLLCMVSYCENDVDCRRLLQLIHFGETFDPSHCAKTCDNCKKGLRWIEKDVTNIAKQLVELVLATGQPCSSSHILEVYRGSLNQNVKKNRHDMLPLHGAGKHLAKGEAARVLRNLVTEGILAEDVKKSDTYGSVSSVLKVNQVKVGGLRSGNQIVLKFPTPDKAPKMGKLDESSISQVNKPVQRQSEMDEVVGH
Length411
PositionUnknown
OrganismHordeum vulgare subsp. vulgare (Domesticated barley)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Hordeinae> Hordeum.
Aromaticity0.06
Grand average of hydropathy-0.428
Instability index45.74
Isoelectric point8.97
Molecular weight46131.43
Publications
PubMed=23075845

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP14882
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     114.92|      42|     139|      75|     143|       1
---------------------------------------------------------------------------
   39-  106 (63.83/31.96)	C..VVFKQSFNRPnlryfvmpktkkcledidrfirenhHKE...CGIIYCLSRMDCEKVAeKLREYGHQASHY
  131-  165 ( 5.04/35.02)	CatVAFGMGINKP........dvrfvihhslpksiegyHQE...CG...........................
  215-  248 (46.05/17.89)	......................................HKEnllCMVSYCENDVDCRRLL.QLIHFGETFDPS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP14882 with Med34 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) PKMGKLDESSISQVNKPVQRQSEMDEVVGH
382
411

Molecular Recognition Features

MoRF SequenceStartStop
1) IVLKFPTPDKAPK
371
383