<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14715

Description Mediator of RNA polymerase II transcription subunit 1
SequenceMKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSLEQDLSKMAVMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYASPSDLLDDKTTSPIILHENNVPRSLGMNASVTIEGTSAMYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLPACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYVPLYELITQFELSKDPDPVPLNHNMRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLVSKITFQHPGRVPLILNLIRHQVAYNTLIGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLYKGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNLPPASSPGEPGLNCFTLPENQGALHFSTGWRRRGRINQAWDTSLLSRCTHSPVPKDGKDMKSTSTYLLLLVSCVFLV
Length616
PositionMiddle
OrganismSus scrofa (Pig)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.189
Instability index51.77
Isoelectric point8.35
Molecular weight68469.31
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14715
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     198.02|      48|      48|     161|     208|       2
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  150-  199 (76.80/41.55)	FSKHLKGLV......nlYNL..........P..GDNKLKTKMYLALQSLEQ.DLSKMAVMYWKATNAGP
  200-  248 (64.46/33.87)	LDKILHGSV.......gYLT..........PrsGGHLMNLKYYASPSDLLD.DKTTSPIILHE..NNVP
  249-  312 (56.76/29.07)	RSLGMNASVtiegtsamYKLpiaplimgshP..VDNKW.TPSFSSITSANSvDLP..ACFFLKFPQPIP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.59|      17|      50|     355|     373|       3
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  355-  373 (30.88/27.51)	VPLNHNM.RF...YAALPGQqhC
  404-  424 (23.71/13.45)	VPLILNLiRHqvaYNTLIGS..C
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.97|      30|     108|     425|     454|       4
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  425-  454 (51.00/27.47)	VKRTILKEDSPGLLQFEVCPLSESRFSVSF
  536-  565 (54.98/30.14)	VKKNLPPASSPGEPGLNCFTLPENQGALHF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.35|      12|     175|     317|     328|       5
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  317-  328 (24.01/15.78)	FVQK.LQNCTGIP
  493-  505 (19.33/11.37)	FIAKvVQRCMSIP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14715 with Med1 domain of Kingdom Metazoa
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