<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14695

Description Mediator of RNA polymerase II transcription subunit 1
SequenceMYLALQSLEQDLSKMAVMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYASPSDLLDDKTTSPIILHENNVPRSLGMNASVTIEGTSAMYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLPACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYVPLYELITQFELSKDPDPVPLNHNMRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLVSKITFQHPGRVPLILNLIRHQVAYNTLIGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLYKGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNLPPASSPGYGMTTGNNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEMCSGSNKTKKKKSSRLPPDKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPPIGTPVRDSSSSGHSQSALFDPDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFPDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGESKFKSNSQADTVDFSIIAVAGKALGPADLMEHHSGSQSPLLTTGDLGKEKTQKRVKEGNGTSNSSLSGPGLDSKPGKRSRTPSNDGKNKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSSGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSASNSGKMKSSKSEGSSSSKLSSSIYSSQGSSGSSQSKTSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSTGMKSSSGLGSSGSLSQKNPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGSEDSMDGQVGVSTNSSSHPMSSKHSMSGGEFQGKREKSDKDKSKVSTSGGSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDRDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSTDRPSRLSPDFMIGEEDDDLMDVALIGN
Length1407
PositionMiddle
OrganismSus scrofa (Pig)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.706
Instability index54.90
Isoelectric point8.95
Molecular weight149033.07
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14695
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     390.19|      49|      51|    1223|    1271|       2
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  384-  445 (44.84/ 7.85)	PMSGTTTPTNT....FP...GG.............pittlfnmSMSIKDRHESVGH..................GED.....fSKVS...QNPILT..SllqiTGN.G....GST
  446-  521 (42.30/ 7.00)	IGSSPTPPH.H....TP...PP.....................VSSM.AGNTKNHPmlmnllkdnpaqdfstlyGSSplerqnSSSG....SPRMEmcS....GSN.KtkkkKSS
  918-  961 (52.09/10.29)	SSSGSKSHHSH................................SSSSSASNS.GKM..................KSS......KSEG...SSSSKL..S....SSI.Y....SSQ
  962- 1004 (44.97/ 7.90)	GSSGSS.QSKT..ssQS...GG.....................KPG.SSPIT..KH..................GLS......SGSSstkMKPQ..................GKP
 1007- 1050 (45.23/ 7.99)	LMNPSLSKPNI.spsHSrppGG.....................SDKLASPM...KP..................VP..........G...TPP.....S....SKA......KSP
 1078- 1116 (47.67/ 8.81)	..SGSLSQ..K....NP...PS.....................SNSCTAS...SSS..................FSS......SG.......SSMS..S....SQNqH....GSS
 1208- 1260 (72.49/17.14)	KNVGSTGVAKIiiskHD...GG.....................SPSIKAKVTLQKP..................GES......SGEG...LRPQMA..S....SKN.Y....GSP
 1315- 1376 (40.62/ 6.44)	LPEYSTEKHKK....HK...KEkkkvkdkdrdrdrdrdrdkkkSHSIKPE.SWSKS..................PIS......SDQS...L..SMT..S..............NT
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     206.39|      49|      50|     152|     201|       3
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  100-  150 (38.53/16.71)	....PLIMgSHPVdnkWTPSF.SSITsansvdlpaCFFL.KFPQPIPVSRA...F...VQKL...Q..
  152-  201 (89.22/53.41)	CTGIPLFE.TQPT...YVPLY.ELIT.........QFELSKDPDPVPLNHNM.RF...YAALPGQQhC
  211-  252 (39.01/17.27)	...........PD...GRSLQgTLVS.........KITF.QHPGRVPLILNLiRHqvaYNTLIGS..C
  262-  290 (39.62/17.41)	SPGLLQFE.V.......CPLS.E..S.........RFSVSFQH...PVNDSL................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.41|      17|      50|    1134|    1150|       4
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 1134- 1150 (33.05/18.96)	DKLKHGVVT...SGP.GSEDS
 1152- 1171 (20.31/ 7.83)	DG.QVGVSTnssSHPmSSKHS
 1185- 1200 (29.06/15.47)	DKDKSKVST...SG..GSVDS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.87|      22|      50|     818|     839|       6
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  640-  665 (27.60/ 6.33)	SSGHSQSalfdPDVFQTNNNENPY.TD
  820-  842 (31.27/ 8.25)	PGKRSRT....PSNDGKNKDKPPKrKK
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     152.45|      37|      96|     766|     815|       8
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  779-  815 (63.15/33.81)	SGSQSPLLTT......GDLGKEKTQKRVKE.................GNGTSNSSLSGPG
  867-  915 (42.80/ 9.94)	.GSKSP..........GSSGRSQTPPGVATppipkitiqipkgtvmvGKPSSHSQYTSSG
 1275- 1311 (46.50/ 9.80)	SHSKSPAYTPqnldseSESGSS.....IAE..................KSYQNSPSSDDG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14695 with Med1 domain of Kingdom Metazoa
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