<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14691

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYEKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLINEEHIHMAQSSPAPFQVLVSPYGLNGTLTGQAYKMSDPATRKLIEEWQYFYPMVLKKKEELKEEELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSVASTGGHITVGQQGLGSVKDPSNCGMPLTPPTSPEQAIIGESGGTQNAVSHLGSQDGGMITMHSPKRSGKIPPKLHNHMVHRVWKECILNRTQSKRSQMSTPTLEEEPANNLATWDFVDPTQRVSCSCSRHKLLKRCAVGPSRPPTISQPGFSAGPSSSSSLPPPASSKHKTTERQEKGDKLQKRPLIPFHHRPSVAEELCMEQDPPGQKLGLAGIDSSLEVSSSRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQETESLDPPSVPVNPALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYCGIRPSNSESSDKWWHSYHLPSIDDVEFRPPELQGERCDAKMEVNSESTALQRLLAQPNKRFKIWQDKQPQMQPLHFLDPLPLSQQPGDSLGEVNDPYTFEDGDIKYIFTANKKCKQGTEKDSLKKNKSEDGFGTKDVTTPGHSTPVPEGKNAMSLFSSTKTDVRQDNAAGRAGSSSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMPAVGTEDRPLGKDGRAAVPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGISSETVTALGMMESPMVSMVSTQLTEFRMEVEDGLGSPKPEEIKDFSYVHKVPTFQPFVGSSMFAPLKMLPSQCLLPLKIPDACLFRPSWAIPPKIEQLPMPPTATFIRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNIFKDRNFDSCCICACNMNIKGADVGLYIPDSSNEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQTTFLPQMEGARKSQEPPISLLLLLQNQHTQPFASLSFLDYISSNNRQTLPCVSWSYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHSWPHSNVLDISMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKDFLTISPFSLPFWERLLLDPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTDELVSEWFSQPWGSEENDNHSRLKLYAQVCRHHLAPYLATLQLDSNLLIPPKYQTPPAAAQGQATPGNAGPLASNSGSAAPSAGSAFNPTSNGSSTNTAASSSASGSSVPPASSSASAPIISQISTTSSSGFSGSVGGQNPSTGASSSERTQGNIGCGGDTEPGQSSSQPSQDGQESVTERERIGIPTEPDSADSQAYPPAVVIYMVDPFTYTAEEDSTSGNFWLLSLMRCYTEMLDNLPEHMRNSFILQIVPCQYMLQTMKDEQVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTELGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCIVNIALPNRSRRSKVSARKIGLQKLWEWCIGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKRLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHPSPNSSPVPSPGSPSGIGVGSHFQHSRASLHHHISVAQTDELLPARNSQRVPHPLDSKTTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNIL
Length2155
PositionMiddle
OrganismSus scrofa (Pig)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.379
Instability index57.78
Isoelectric point5.64
Molecular weight236694.16
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14691
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.87|      27|      28|    1008|    1034|       1
---------------------------------------------------------------------------
 1008- 1034 (48.71/26.86)	PDYLNTPQMNTPVTLNSAAPASNSGAG
 1039- 1062 (44.66/23.90)	P...ATPRFSVPTPRTPRTPRTPRGGG
 1078- 1096 (26.51/10.61)	GSPASTPSTTRP..LNSVEPA......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.13|      20|      28|    1130|    1156|       2
---------------------------------------------------------------------------
 1130- 1149 (40.30/38.25)	CICACNMNIK.GADVGLYIPD
 1160- 1180 (33.83/15.15)	CGFSAIMNRKlGYNSGLFLED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.75|      18|      19|    1611|    1628|       3
---------------------------------------------------------------------------
 1611- 1628 (33.59/17.63)	G.GQNPSTGASSSERTQ.GN
 1630- 1649 (26.16/11.81)	GcGGDTEPGQSSSQPSQdGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.45|      39|     363|     461|     503|       4
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  463-  503 (66.77/47.08)	SSKHKTTERQEKGDKLQKRPLIPFHhrPSVAEELCMEQDPP
  829-  867 (70.68/37.10)	SSKMPAVGTEDRPLGKDGRAAVPYP..PTVADLQRMFPTPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     151.07|      27|     113|     435|     461|       5
---------------------------------------------------------------------------
  435-  461 (53.08/23.24)	VGPS..RPPTIS.QPGFSAGPSSSSSLPPP
  551-  573 (33.71/11.77)	ISP...LPPTLSpQP...RG.QETESLDPP
 1540- 1564 (34.80/12.42)	..PG..NAGPLA.SNSGSAAPSAGSAFNPT
 1566- 1593 (29.48/ 9.27)	NGSStnTAASSS.ASGSSVPPASSSASAP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.29|      17|      17|    1232|    1248|       6
---------------------------------------------------------------------------
 1232- 1248 (30.27/18.66)	TQPFASLSFLDYISSNN
 1251- 1267 (33.02/21.13)	TLPCVSWSYDRVQADNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.13|      20|      21|     947|     967|       7
---------------------------------------------------------------------------
  947-  967 (33.32/16.01)	MFAPLKMLPSQC.LLPLKiPDA
  969-  989 (36.81/14.80)	LFRPSWAIPPKIeQLPMP.PTA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     193.39|      58|    1264|     156|     215|       9
---------------------------------------------------------------------------
  156-  215 (99.16/70.63)	PVNKSeHLSCAFTFFlHGESNVCTSVEIAQHQPIYLINEEHIHMAQSSPAP..FQVLVS.....PYG
 1423- 1487 (94.24/58.69)	PENEA.LLEGAKTFF.RDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQklTDELVSewfsqPWG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.19|      18|      22|    1999|    2016|      11
---------------------------------------------------------------------------
 1975- 1991 (21.38/ 9.54)	.TALNMQSS...QLNTPQDAS
 1999- 2016 (31.10/17.92)	PTSSTIQVA...PANYPNEDG
 2019- 2039 (26.70/14.12)	PNNDDMFVDlpfPDDMDNDIG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     444.99|     138|     394|     230|     375|      12
---------------------------------------------------------------------------
  230-  375 (225.28/136.20)	PATRKLIEEWQYFYPMVLKKKEELKEEEL.GY..DDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSVASTgGHITVGQQ...GLGSVKDPsncgmpLTPPTSPEQAIIG.....ESGGTQNAVSHLGSQDG.GMITMHSPKRSGKIPPKlHNHM
  622-  771 (219.71/114.79)	PSNSESSDKWWHSYHLPSIDDVEFRPPELqGErcDAKMEVNSESTALQRLLAQPNKRFKIWQDKQPQMQPLHFL.DPLPLSQQpgdSLGEVNDP......YTFEDGDIKYIFTankkcKQGTEKDSLKKNKSEDGfGTKDVTTPGHSTPVPEG.KNAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.14|      23|      26|    1739|    1764|      13
---------------------------------------------------------------------------
 1739- 1764 (38.99/32.32)	QvfyIQYLKSM..AFSVYCQCR...RPLPTQ
 1766- 1793 (30.15/16.06)	H...IKSLTGFgpAASIEMTLKnpeRPSPIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.34|      24|      25|      60|      84|      14
---------------------------------------------------------------------------
   60-   83 (45.77/28.57)	FIRCLQANLLCV............WRRDVKPDCKEL
   86-  121 (38.57/17.49)	FWWGDEPNLVGVihhelqvveeglWENGLSYECRTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.35|      20|      25|     784|     806|      18
---------------------------------------------------------------------------
  784-  806 (28.18/30.08)	DNAAGRAGSSSLTQVtdlAPSLH
  809-  828 (34.18/25.46)	DNIFDNSDDDELGAV...SPALR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.55|      18|      25|    1338|    1355|      19
---------------------------------------------------------------------------
 1338- 1355 (33.04/23.52)	KKRTGRTWENIQHVQGPL
 1361- 1378 (32.51/22.98)	HKMAGRGTYGSEESPEPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14691 with Med13 domain of Kingdom Metazoa
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