<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14683

Description Prostate tumor overexpressed 1
SequenceMPSGAPGASKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSAAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRVMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVAGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQGNFLNGIRRVIANQQQVLQRNLEQEQQQRGVSASEQGTLGTTTAQRDGGQRPEMSPRTVPPPPPVCFPIKVF
Length435
PositionUnknown
OrganismSus scrofa (Pig)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Suina> Suidae> Sus.
Aromaticity0.07
Grand average of hydropathy-0.231
Instability index48.74
Isoelectric point9.76
Molecular weight47717.74
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central
GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP14683
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     178.20|      27|      74|     101|     127|       1
---------------------------------------------------------------------------
  101-  127 (56.13/40.39)	PCQVYVNHGENLKTEQWPQKLIMQLIP
  178-  196 (31.46/19.38)	PCEVRVLM..LLYSSK..KKIFM....
  262-  288 (54.24/38.78)	PSHVYVNQGEILRTEQWPRKLYMQLIP
  339-  360 (36.37/23.56)	.CEVRVLM..LLYSSE..KKIFIGLIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     337.48|     102|     163|      58|     219|       2
---------------------------------------------------------------------------
   32-  175 (162.55/91.42)	SAQPG...APSMAGTVAPGgvsgpsaaqlGAPALGGQ.QSVSNKLLAWSGVLEWQEkPKPasvDANTKLTRSLpcqvyvnhgenlkteqwpqklimqlipQQLLTTLGPLFRNSQLAQFHFTnRDCDSLKGLCRVMGNGFAGCMLFPH
  201-  335 (174.93/88.75)	YDQSGfvnAIRQVITTRKQ........avGPGGVAGPvQIVNNKFLAWSGVMEWQE.PRP...EPNSRSKRWLpshvyvnqgeilrteqwprklymqlipQQLLTTLVPLFRNSRLVQFHFT.KDLETLKSLCRIMDNGFAGCVHFSY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP14683 with Med25 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LEQEQQQRGVSASEQGTLGTTTAQRDGGQRPEMSPRTVP
2) MPSGAPGASKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSAAQLGAPAL
385
1
423
62

Molecular Recognition Features

MoRF SequenceStartStop
NANANA