<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14672

Description Uncharacterized protein
SequenceMAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLAILAKKELPLAKSGVPQVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQPTDPNLEWTQISTRYLREQLAKISDFYHTASSTGDGPIPVSAEVQQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPSLLATHSPHMMLGPNNSSIGAPSPGPPGPGMSPMQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSASLAGSGLPVFQNVLLRFLDTQAPSLCNFSCEIYRFLMEFASSQRIPNSECEKWKFFIRHDVFSHDALHIFSPMPGESCENANPSLGRRMSINGEKLAKREKPRELIFPSNYDLLRHLQYATHFPIPLVSCCFLYFTP
Length707
PositionKinase
OrganismCavia porcellus (Guinea pig)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Caviidae> Cavia.
Aromaticity0.09
Grand average of hydropathy-0.330
Instability index48.68
Isoelectric point8.01
Molecular weight79672.39
Publications
PubMed=21993624

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP14672
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.79|      16|      17|     586|     601|       2
---------------------------------------------------------------------------
  586-  601 (30.95/19.39)	RFLD..TQAPSLCNFSCE
  604-  621 (24.84/14.13)	RFLMefASSQRIPNSECE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.09|      12|      17|     122|     133|       3
---------------------------------------------------------------------------
  122-  133 (20.51/11.17)	GNKPLAILAKKE
  140-  151 (21.59/12.10)	GVPQVPILSKKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.05|      15|      17|     315|     329|       5
---------------------------------------------------------------------------
  315-  329 (24.98/16.71)	LLLSDSPSLLATHSP
  331-  345 (28.07/19.80)	MMLGPNNSSIGAPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.53|      12|      18|     363|     376|       6
---------------------------------------------------------------------------
  363-  376 (17.86/17.85)	LSCAqhGPLVYGLS
  384-  395 (25.67/16.62)	LCCP..SALVWNYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.46|      12|      24|     450|     461|       7
---------------------------------------------------------------------------
  450-  461 (24.54/15.44)	EV..RWSFDKCQES
  475-  488 (18.92/10.40)	EVldRHCFDRTDSS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP14672 with Med12 domain of Kingdom Metazoa

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