<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14666

Description Uncharacterized protein
SequenceMTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPITKEALEETRLGKLVNDVRKKTKNEELAKRAKKLLRSWQKLIEPAQQSEAALRGANGGAHNCRPEPGAIVPKGIPDLKHRNDLQRLPGPRLDRLGSRKRRGDQRDLGHPGPPPKVSKAGHDLLGPNCSPRPTNGISGSPESFPSPVDGSGLLSSEGSRLEADENDQLGGKVPVNAVRPHPGSPGLGRPPGPCLQAKVEETPGPPHPRAPSRCSFSPRNSRQEGSFARHRSPYTPKGSVSSPLPRPSVLEATQVPSPLPPAQPSTPPVRRMELLPSAESPARWPEQPEGHQRLAGPGCKAGLPPAEPHLPVSGFSPDSSKADSDAASSGGSDSRKRKRYRSRDYMVNLDGQVAETGVKPVRLKERKLTFDPMTRQIRPLTQKEPARADSPALTEQPPRTDLEKQEAKVSLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLRQEESSRRGARQPHVLVPHAPPATLPGLSREVTQDDLERLEAGQWPGVNGCRDTQGNWYDWTQCIALDPHGDDGRLNILPYVCLD
Length583
PositionUnknown
OrganismCavia porcellus (Guinea pig)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Hystricomorpha> Caviidae> Cavia.
Aromaticity0.04
Grand average of hydropathy-0.866
Instability index69.83
Isoelectric point9.45
Molecular weight63685.89
Publications
PubMed=21993624

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14666
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     419.16|      89|      90|     358|     447|       1
---------------------------------------------------------------------------
  191-  241 (74.89/21.15)	......SGLLSSE.......GS........RLEA.DENDQLGGKV.......PV..................NAVR.P..H.........PGSPG.LG.RP........P..GPCLQaKVEE
  246-  348 (108.49/33.36)	PHPRAPSRCSFS.prnsrqeGSFARHR..SPYTPK.......GSVSSP.LPRPS...VLEATQVpsPLPPAQPSTP.P..VRRMEllPS.AESPArWPEQPeghqrlagPgcKAGLP.PAEP
  358-  447 (145.33/49.02)	DSSKADSDAASSG.......GSDSRKR..KRYRSRDYMVNLDGQVAET.GVKPV...RLKERKL..TFDPMTRQIR.P..LTQKE..PArADSPA.LTEQP........P..RTDLE.KQEA
  458-  540 (90.45/26.80)	TNWK...EL..............SRNEiiQSYLSRQSSL.LSSSGAQTpGAHHFmaeYLRQE......ESSRRGARqPhvLVPHA..PP.ATLPG.LSREV........T..QDDLE.RLEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     105.37|      18|      19|     114|     131|       2
---------------------------------------------------------------------------
   95-  110 (26.22/ 9.51)	RGANGGAH..NCRP...........E..PGA
  114-  131 (33.88/14.40)	KGIPDLKHRNDLQR...........L..PGP
  135-  153 (23.38/ 7.70)	R.LGSRKRRGDQRD...........LghPGP
  159-  187 (21.88/ 6.74)	KAGHDLLGPNCSPRptngisgspesF..PSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14666 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AHHFMAEYLRQEESSRRGARQPHVLVPHAPPATLPGLSREVTQDDLERLEAGQWP
2) AQQSEAALRGANGGAHNCRPEPGAIVPKGIPDLKHRNDLQRLPGPRLDRLGSRKRRGDQRDLGHPGPPPKVSKAGHDLLGPNCSPRPTNGISGSPESFPSPVDGSGLLSSEGSRLEADENDQLGGKVPVNAVRPHPGSPGLGRPPGPCLQAKVEETPGPPHPRAPSRCSFSPRNSRQEGSFARHRSPYTPKGSVSSPLPRPSVLEATQVPSPLPPAQPSTPPVRRMELLPSAESPARWPEQPEGHQRLAGPGCKAGLPPAEPHLPVSGFSPDSSKADSDAASSGGSDSRKRKRYRSRDYMVNLDGQVAETGVKPVRLKERKLTFDPMTRQIRPLTQKEPARADSPALTEQPPRTDLEKQEAKVSLQSPFEQ
490
87
544
457










Molecular Recognition Features






MoRF SequenceStartStop




1) RKRKRYRSRDYMVNLD
2) RRMELL
375
310
390
315