<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14629

Description Uncharacterized protein
SequenceMRGHEQSSIPLYKSQPPAWLPKAHSAGELGYPGFYPPHSGQEEDILSESNIKNGFVLPPSVQMETFSAQSTVTESLHGQDTISKLEELMNEVFARRLHQIPSIPLSTFRVPSRVTLNDTKRQAWFADLANPDVPLNKLGKSVPHGAKGHDLLDLLHSNNIAIPRAVWFLRVFGANETAGLRNRPSYNPTQYSVEWAGVVTGYMKKQLADIALPSAPRPGMNIKQTFKGVLADTGTRDRWISRFTYCLKLLRAFYKEGLVDRRTFLVWVVHQMGICNLAQAGFIARIADEYLEGMMSSRPLTRPFVEACVSKLSEIGSSASREFLVDTEGLLKAILQRFCLALPDAFVSPRMWATHSSLLLAVLTENIMDQTFDGQNPSEIHQVLIRNVADIQRRNEAMLFYNLPPLASDRLGSSVLDIKLLNSISRTTDINSISFFSDSILDDPKHKLDMLLTWSITPLQFGDHRPFAAITLIRNWRQRAGERALRREDRSPDEFIQDQLFNWLDSSEVAGDPKNTRAVALLFGKLIQRELFSYGSYIQRLIARGEPGLSFNDAVESRHRLFLRWISLSEPSQLNQRKVTLYGVRARDTPEEGTERQMRKEIRAVMPQLFEGGPEPLLKSPDALFRQCKTFVSSPLYEQVRTLKLWLLPILEKSISSISVIDNVLKSYCIAVELMAETKCFRSILNLTLCLLEHASTTDSLNTAIDTLRRFHTLWSCMDVVGSIVTSLQTAHQIWKSKGMQTRVLLVLLKELDDNRFLSAQARDQLNAEISYYSMTLQPVIVGHPEPVPSVLPEILLLAGDYEEDAPSTLANGLWIKYRMSFDWAWKVWDNTIASLRQIPLMVPDTEGRRGCALRYATFLRHVDHLLPTGLDDHVLGWFLGPGKSEVVNLTADVWDIVTLLLLGLVVHGALKTTTIMTGLVYPAWQCASSSVELPLQQMEVFLAAANNLVQGLLLRGEGSSGIMPPCDLFDVQRLQTRKQDVYCEPHFPALVSNIPILVSLENNERIPEHLRTELKAIRHSLYEDDNFRQGTFRNLDALREAFEQAMQLKENTSPEVGDRTMAALRMIFSEAPDEDIEISSWPEKSSFLSPWMISATTIQLQFFLKQMERSINKESHAYDTACMTLDKLTSVIFDHTLSSDEACFVTQMTQGVGSAVAGKIINNGLRFLTGVLRDPSSDTGTSLARAGESFRILIYVAEPLRQESAQLPVLDPDVQDMFFSTLCSKFASIEEATHNPDAMTVDRTDFTQEVVLLARFLQFDLSFEGAWTASTTESSRKLCASLYRLTLLFASGNTFDPIAYPLLLDTLYYLIDEAPTSTKMNAFDPFINYPDITPSDFAPDIPFHYLTQLRSLLPHLPAVSSVADLASCHRDASGKLVQDAPVVNRPWEWIENLGEPSVPEERFREGEDRVKYQVKNSGSISLDTFGARMTGEGIITSKYDDERIEANMRMFEDGLSADNVFKRDWRETRLTVEIEGMALTAGRKAGMSGSQELGPRVVSPGASSSRIGKSPARSSLHRSTNSTRSGSVEIIDVDSVSSSTMRKGVKRKAATSDDEVIIVDGPSKGGSSSSKKSKPKPKARKR
Length1583
PositionKinase
OrganismArmillaria ostoyae
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Physalacriaceae> Armillaria.
Aromaticity0.08
Grand average of hydropathy-0.210
Instability index46.70
Isoelectric point6.01
Molecular weight177327.42
Publications
PubMed=29085064

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14629
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.17|      27|     323|    1181|    1243|       3
---------------------------------------------------------------------------
   56-   82 (47.33/17.27)	VLPPSVQMETFSAQ....STVTESLHGQDTI
 1210- 1240 (42.84/20.80)	VLDPDVQDMFFSTLcskfASIEEATHNPDAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.42|      15|      46|     528|     547|       5
---------------------------------------------------------------------------
  528-  547 (21.91/27.00)	QRELFSYGsyiqrLIARGEP
  576-  590 (27.50/17.65)	QRKVTLYG.....VRARDTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     261.90|      70|     439|     957|    1030|      11
---------------------------------------------------------------------------
  957- 1030 (114.71/86.67)	GEGSSgimpPCDLF....DVQRLQTRKQDVYCEPHFPALVSNIPILVSLENNERIPEHLRTELKAIRHSLYEDDNFRQ
 1355- 1394 (46.03/24.37)	.................................PHLPA.VSSVADLASCHRD..ASGKLVQDAPVVNRPWEWIENL..
 1395- 1464 (101.16/66.13)	GEPSV....PEERFregeDRVKYQVKNSGSISLDTFGARMTGEGIITSKYDDERIEANMR....MFEDGLSADNVFKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.10|      53|     439|     593|     648|      12
---------------------------------------------------------------------------
  593-  648 (85.79/61.09)	GTERQ...MRKEIRAVMpQLFEG.GPEPLLKSPDAL...FRQC...KTFVSS.PlyEQVRTLKLWLL
 1031- 1094 (69.31/39.23)	GTFRNldaLREAFEQAM.QLKENtSPEVGDRTMAALrmiFSEApdeDIEISSwP..EKSSFLSPWMI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     286.13|      92|     891|     354|     451|      13
---------------------------------------------------------------------------
  354-  451 (139.80/109.02)	THSSLLLAVLTEniMDQTFDGQNPSEIHQVLIRNVADIQRrnEAMLFYN...LPPLASDRLGSSVldIKLLNSISRTTDINSISFF........SDSILDDPKHKLDML
 1248- 1350 (146.33/95.68)	TQEVVLLARFLQ..FDLSFEGAWTASTTESSRKLCASLYR..LTLLFASgntFDPIAYPLLLDTL..YYLIDEAPTSTKMNAFDPFinypditpSDFAPDIPFHYLTQL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14629 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GMALTAGRKAGMSGSQELGPRVVSPGASSSRIGKSPARSSLHRSTNSTRSGSVEIIDVDSVSSSTMRKGVKRKAATSDDEVIIVDGPSKGGSSSSKKSKPKPKARKR
1477
1583










Molecular Recognition Features






MoRF SequenceStartStop




1) TMRKGVKRKAATSDDEVIIVDGPSKGGSSSSKKSKPKPKARKR
1541
1583