<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14619

Description Uncharacterized protein (Fragment)
SequenceMLPSPMPSTSEVDSVEDSSEEDDAYPENGVPSWFDTHSGERILRKSNIRMGTADVYKQNKNQEEDMLTTERLKKGYQMPVTQYELQSLVFNASENKLTRLDRAQKRTQSMIASIIHKKGEYNMNYDRDRKATRDSLPRFAVYHYKRILQDRVKFFSALSRGTPLQYLAQKIPSFKKKEFLFHEFYDYNVPFDRALWCVKLVSIIGFASKTQKKTLLDVATLELSQACGKTTNHLLHHLVKNVKEEQGYAEACRMWKYKTKFMRMMFQDGVLDKQEFLNDLTEAFNIFFIKSSIFKDDILQKFMAYFISFSEDISSNLILSRRASTLLCQGLGVLSDTEDMRRKFEAYKAENEDEFDENGTWFAAGKPIPIKGREDMISDSTSVSSVHTEDLIDFFDELPDEPYFEDEDDERTPEERAEEIYEQREAWKEEIAKRVAERQAEIDKEKEAAAVNRRTIKQEKIDNSYDRSMGTTSHSSFMVHIKEEPMDYDEYSMSQVSYPVLLPPPPPPPVPTRFLQPYNEDEPEFSWKEPTEPDVRYIRETEVTPPPAESDENRMEASSPIVEYEPIPLKPLYSLPSKKYPEGHEFSHLKQKPKPPCPIIGRYGFLTFPLWQQLGGSAIDPDNEDVMDFSNPTPPEAPPPAPPVEFVSSPSESPAPENEKDDDEGEKKDEDKEEGEKSKEKRDEDKTSEDHTNDLDVPVDPELASKRNSSTNSKDDENDVTSKEGGSEKSPKTSKPDEETEAAEKDKDVDSAEKTDKDGEATENPPIDMSTIVIPELNLDFPDPFTLAEPMELDPTYTSDNLIIPLDDDYMDVDQPEMAELPVADQEDDCMIIAVQEKKVDEDDCVVIAVVEPEKEKTPEVDEEPASEPGKASVETPVPMETSVPMETTTPMDTTAPIETIPPIEHIPPMEINAPMIMKPPQKPQKETTRERRVSDSVYVPLNLTPEEIENLKIPTKKALEKGKEIQAIAEEIRLRALRDKEWENKTGTHPGFKEYDYTTMMEPIYLMSAMVQYLACVTPESFVWNNLVIQQEPRRHKILPQLCGSPLDYLPCDLHELPVPEGNEEALDTLRLRHLEIVRRSQAAEEKWLPNGADVLQYGRIIDTCVDVIGVMDNIDVEKPDAIPNAANRLFKFREKFAKEEALLRSKLMFKWCITDEREGSFRAAYIAKLLRFGMDQGPENTIGGWQPMDLFFNFMVTEGPKPGIPMYQKQFDAIVAIMIEMLREKIFSITDIIRELEKEGDLDYNAPLMARQRKQKLPKIPKQFKKEQVQDETKLIQFTTEYTPKRLFMGRKLDLLEKMIIVLPQLDVNEDTDEFRIRRLLLFGIKPAGNYYFRRIRAIYKNIAKEFETKSYIHFNRHSKVTTLHKKLNQTRLEELLRQFRAQTYYDQHIILERLVYNYIDGIGAFLEKCSDKVPAPEIVNVICEMYEFSMDISSIFDFFEMAVPFLKSVDEMIAQLRMDILPDMYYAETGFIFVSFFMKHWQRFLLHPNACGIVNQCYHLIEDMIRADDHLITGWGRTIAIFAFHARKAITAAGLQTEPFDAKDQYFWRVFPNTQQVNMDVNCFNEEFAACKLKLKGAALRYDSYSDFKWIVHNLKPNTKKVPPSKRPNARYSFVIRAFIEARKHSRNFDRLNELANYCANVTANDPPLSEYWIGAIKGLCCLSCHDTFPFKEMGQFIDISDCSTHYSFTTFISCLAGKSAFYIPRLLAELAKHVFPLMLGTHGRLTSQKTRDVRRKVTSKTTESRNLSEAEPGVCLCLLIIAGLCCAGDEPFGLAVHYRGIEKKKKRFKNTADERILHLFHWFEMDNAMFRALGHISQLLEALQPRFRDANLILPSVFQIKNPQKILSDSHREKAPYRPQFLFNIAKTVLFTICEQDWVTLRMFRFVKSRRMEAFNQDKLKQNCLGQQILRLSLRRITERDNVQKLFEAHKISKKVTVDKVLSFMNIWNFRATLFDLTLMIKEISPDANSKYAQQGAIAADALMSEIGKCCRDMFLTAYKTNIKMPTLKTLIDFRFSDINKYWLIAPLVRMCPKPTNIAVAHTNSTIGTVAAKFLKEAAMLMDTRPTTPKDRLLQCSWAMSKIPFINMILTCLRCEKSQQSKDSFLQALYVQLQREIHRDHHKRSDWTNRPEHRDCTVLRMNLITYIYKEILKPTHVEPWGLLIFQLMYHGIINQAREKLVFETCYDMLHHMVLWTLVEGDNMNTHDRYGSIRVRWPQYAGLMKKIRKEVQDRYIDPSRRSLLRFIPIGKVQMTSVAYKKFNIKNKNSPKSSKKYISGEGLKNGRYALLPEEKVKTNAFDHILETPEVIQKGGWRFRNFQTTRLDKVAKPVQSALRPLIAHKHMLEFNRPQLIMSDNMFDDVFLSPPDIEVTKVVDPPTPTNEEEEEAGKKKADTDKTPEKADGAKKTDEESKTDEEKKKDEKEGEKPAEEAEADKDKEKENDKEKEKTAEGAAKNDEVVAPEAEKAKTAEAEGTPTPATEAKEGDTSTPKPAPVARSSPATRGRGGGRKRTSGARAGGPRAKRTNSKADAKADAAATTGWTGGNTSSTGGGGGNYHGAMRANQPPMSNGSSDETKEHIRNLLNRKQEKRNSTYGQFATPNPGPLNPMTHRASAAISAEDRKKIMEEQMVMKLQQQQQLIEQQNRQKEAREREAREHQERMAQIEQQKQEERKRAIAESNRLMEAQRQQLREQEEQRRREEQLRIQEEARQAFLAEQRRQQEEMRRREAEERARREAEERMRLQREAEERERERLRLEAERQRREAEERERIRQEQERIRLEMEEKARREKEEAMRLEQERKEQEAARAREVAAAAAAAAAREQEHRARLEQQHRLNQQNQYMNQQAASYGQQQPQGQPPSYQQSSYQNPTGYPQQAQQPNQPPAYQQPSHGHQQMQPGQQQHQPPAYQQGNNQMQMSMHQQQQQQQQIRQQAAAQPQFGNQGGMNPQAQQQAYPGYSQQMGQAQAGQQAIPQQQQQRNPFGAQPEMQQPGGAKMLMPTKPNEAHAQQYQHTQNQMALSQKEKEKQYFQAKNAQAGQATGQNPRFGDATAGNASGFGRNASFGQQQQPSAPEFSATAQVPPTNPTRLLPGPTVNPNPMQVQQTAMQNYQQQQQPVLGQPAPMQPGGPTGQQQPAAQQQQYNRPMHTTPTPDMSVRPTQPGSMSQMQNRMGPGSGSQGYAQPGQNVSGGYQPAQQPGQTAYPQQQTNYAASNPQMSQHQQPAQNMNQPVQAQPQQQNAQQAQNPGQYPRPNQEGTYPQQGYNQPAAAQNYQRPEQQQPAPQNQWPAQTQQANQMRQQPAPQTQPQQQAQFGRTEQQQQQYQQAQAQTQQAQQAKNPMASQNASFRGGFPGQQQQQGYEQQAAQAPVHQNPPIHHQQQPNPQTTPQYPQPPQQQAAQQPVHQQQQPQQQQQNRYSGYAGSNASSNILNQSMEESGLNQGYTSTNTSSQQTSSSHMQQNAYGMQQNQMHQQQMTQPAQQPQQQSRMSQPGIGQPGMGQSTMGQPGMVQPGIGRSGMSGMGQPAPQQVQQTQPVQPAQQQQPQAQRGMNPMGGAQLPPYSMGQQQQQATQQQQQDHYRRMQEAQQLQLQQQQQQQRTAQAQAAQAAQAQAQAQAQAQAQAQAHQAQQNAMGIPQQPAAQQQMQGGYGNQMQQFPSLQHRGQGPQAHGMGAMGAQQQVQQPAANQYYHPQQQPDQRMQQQQQPQQPGQQQQQHGYMGQYPNQQPHQY
Length3726
PositionKinase
OrganismCaenorhabditis latens
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.07
Grand average of hydropathy-0.924
Instability index56.36
Isoelectric point6.27
Molecular weight426273.50
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14619
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     131.20|      18|      18|    2722|    2739|       1
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 2887- 2908 (29.08/ 8.84)	PPAYQQPshghQQMQPGQQQHQ
 2925- 2940 (27.08/ 7.54)	QQ..QQQ....QQQIRQQAAAQ
 3320- 3337 (24.77/ 6.03)	QQQYQQA....QAQTQQAQQAK
 3603- 3619 (24.88/ 6.11)	AQAAQAQ....AQAQA.QAQAQ
 3620- 3637 (25.38/ 6.43)	AQAHQAQ....QNAMGIPQQPA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.49|      25|      26|    2723|    2748|       2
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 3286- 3316 (25.10/ 6.58)	QwpaqtQQANQMRQqPAPQTQPQQQAQFGRT
 3671- 3695 (35.39/ 8.52)	M.....GAQQQVQQ.PAANQYYHPQQQPDQR
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.79|      15|      19|    3487|    3505|       4
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 3463- 3477 (28.27/ 6.58)	GMQQNQMHQ....QQ.MTQP
 3491- 3510 (21.52/ 7.90)	GIGQPGMGQstmgQPgMVQP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     153.87|      19|      19|    3109|    3127|       5
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 3109- 3127 (37.58/14.89)	MQNYQQQQQPVLGQPA.PMQ
 3190- 3207 (27.45/ 8.16)	SGGYQPAQQP..GQTAyPQQ
 3238- 3255 (31.63/10.94)	QQNAQQAQNP.GQYPR.PNQ
 3388- 3404 (25.55/ 6.90)	.QYPQPPQQQAAQQPV.H.Q
 3696- 3714 (31.66/10.95)	MQQQQQPQQPGQQQQQ.HGY
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     116.44|      18|      19|    2419|    2436|       7
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 2398- 2415 (22.91/ 9.03)	DTDKTPEKADGA....KKTDEE
 2419- 2436 (28.89/13.52)	DEEKKKDEKEGE....KPAEEA
 2441- 2457 (24.31/10.08)	DKEKEND.KEKE....KTAEGA
 2479- 2500 (19.03/ 6.12)	TPTPATEAKEGDtstpKPAPVA
 2502- 2519 (21.31/ 7.82)	SSPATRGRGGGR....KRTSGA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.92|      18|      19|    2952|    2969|       8
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 2952- 2969 (34.52/11.61)	QAQQQAYPGYSQQMGQAQ
 3217- 3232 (25.83/ 6.42)	QMSQHQQP..AQNMNQPV
 3535- 3552 (28.57/ 8.06)	QPAQQQQPQAQRGMNPMG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.05|      17|      19|    3044|    3060|       9
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 2862- 2878 (26.07/ 7.22)	QPPSYQQSSYQNPTGYP
 3371- 3387 (28.98/ 9.01)	QNPPIHHQQQPNPQTTP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.25|      17|      19|    3555|    3573|      12
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 3261- 3278 (22.97/ 8.06)	QQGYNQPAAAQnYQ.RPEQ
 3639- 3656 (22.27/ 8.18)	QQQMQGGYGNQ.MQqFPSL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.43|      21|      21|    2650|    2670|      14
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 2642- 2665 (30.98/14.40)	QLIEQqnrQKEAREREAREHQERM
 2666- 2687 (28.45/12.52)	AQIEQ..qKQEERKRAIAESNRLM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.58|      16|      20|    3423|    3442|      15
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 3423- 3442 (23.39/23.10)	NASSnilnQSMEESGLNQ.GY
 3446- 3462 (25.19/13.52)	NTSS....QQTSSSHMQQnAY
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.98|      19|      20|    2999|    3018|      16
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 2999- 3017 (34.94/24.58)	MLMPTKPNEAHAQQYQHTQ
 3020- 3038 (31.03/14.82)	MALSQKEKEKQYFQAKNAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.71|      18|      20|    1171|    1188|      17
---------------------------------------------------------------------------
 1171- 1188 (34.89/18.38)	LLRFGMDQGPENTIGGWQ
 1193- 1210 (35.82/19.10)	FFNFMVTEGPKPGIPMYQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.71|      13|      20|    3154|    3171|      18
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 3154- 3171 (21.25/18.77)	PDM.SVRPTQPGsmsqmQN
 3175- 3188 (22.47/ 8.19)	PGSgSQGYAQPG.....QN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.22|      18|      18|     794|     811|      19
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  794-  811 (32.42/19.16)	DPTYTSDNLIIPLDDDYM
  814-  831 (32.80/19.48)	DQPEMAELPVADQEDDCM
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.66|      11|      18|    1041|    1051|      27
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 1041- 1051 (21.71/13.63)	PQLCGSPLDYL
 1061- 1071 (18.95/10.68)	PEGNEEALDTL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.86|      16|      18|    2085|    2100|      28
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 2085- 2100 (29.55/21.38)	SKIPFINMILTCLRCE
 2105- 2120 (26.31/18.07)	SKDSFLQALYVQLQRE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.58|      22|     284|    3062|    3083|      29
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 3062- 3083 (35.69/12.11)	RNASFGQQQQPSAPEFSATAQV
 3348- 3369 (39.20/14.19)	RGGFPGQQQQQGYEQQAAQAPV
 3514- 3533 (33.70/10.93)	RSGMSGMGQ.P.APQQVQQTQP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14619 with Med12 domain of Kingdom Metazoa
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