<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14618

Description Protein transport protein sec16 (Fragment)
SequenceMSLFWEKGLQQQDTGQPAQQQGQWDFINLGGAPAPQHQWNPSVQQQQPQHQQQNSYYYQSAPTQQQPQQPHTNHSAQQQQYNVNSQHQQSAEQNYQQQQWVAHQQSQHQAPPPQTQQTQHQPQLPKPKKAQQTVIEHTPLLPPAQQVQQVAQQAPNFTPAPPVLTPSFQNVESHQQYYQQQPQQQSQPMYQQYVNSKPEEPAAPAYYPPTPVTQLGSAPTSKEVTPEPQTKPAPAVQVAPVTQKPAAPTPKPPVLAPPAIPKKEEHLSVAAPIVIEDAKPKVTPTSSEDDWEKADMEIQRVEDENKRQKASQVAPEKPEESRESSSLGGSWATQDTEPSERNSVEPVEIVEHPVSIEVDIEEKTPRVSVSENQATPTIVNMSTSLPDDRQETPEAGHPNQSTSVVINSSGSPLEAIATSTPKEMRPEKRSSVSSQGTIGTEKSRSKKNTEKSERRNYTDMFNKHEPQNHIVEKEEESGNNSDSTMASGRPDFVRGEARASYREYKKTYHAIVDRLNFMRANQNHSDFRPSSKLANPLLAAAGLSRQHPAIRRESLGARNDGRASVPLHHSHSFNDNIYSEQNGGRRSRVSRLDSSGRPSSRHAPGYASVNHSQVNPYDQRGYVQQQNSLFRHGRHSAMAGQYDPRRPYGAEQYPGAVYGQEPQETSSISESDEDEGESDYEIQEYNMHHRQAPSEHSYHPSQGGDDEGKTLYYCGVVHVNMDLWYRIKEKTGIPAGFANLNAIQKAAFMFYTVVFKQPYPNVDTFHNRFNREFFRYKCDGQSEDAALFQICRTMQEQYEARRKEKELAYQTMKATLFSDDNSIDGQSENNSVYAESLNACDVYNNGPLKFSCPHSFLNISHGGQIISIQPDQSISAVVFDDIKSVLKDIPTLQIKDAAMSFKGPLIPHQSASHTVRLYITKQIENIKRSAVAMENPEANDVVESLLVWQLLETMVKQQGNITGPDIAEILAKVASQPVNIEAPPQMSNITPALNQFTQFLLGGHIDEAVESAMRNGLFADALVLTRRLFPNDERKIEQIESRFLQTRSMNNPVTTLVSVAKGEVPPVLTNPPLDDHLSWRTHAAIILANLDQRGTALSTIHQLGRALAKRDYHSAADFCFLVCGVLGGEKENPFKPVPTPEGEEDYRRYISLVNSDIPDNEANPKCQYGFLLTDLHATEIFDYALRLKPDRESLLANSVEYQTARIKYAKLLANHGFTSDAWRYCLEIARTIWVYVTNFYQDDLMELVDLAESLHHRADVNPEDTEWIQSLRSIVQGGYGRVTPTTQATTKQEVTDANQSYGYEQHPETVYEPKVEPLQPTVLVPTAPELAPTPTPSAFTAPIPSEHQTPPEIAQQHQQNQFHADVRYEPATPTGSVHQEQHAQQYESPFSYHSTQDQYQHPDDGFTTPPDFNDGPLTMASSPQASAPQLAPQLAEKPAAQPQPVVQAPPPPQKHQQYSDQQQYQQQPPQDDNQNRNQLNSDNKNQSQGWLKSIQTKVQKALPGQNPMNLPEDKNPSIVWDESQNKYVGAGVEPEPVAPPPPIASATPAPPTGGGLRAARGVSRYAKVGLGNSPSNASQAPAGMMPQAPPTASFGFMPAPVDDDADSVDPFSGQANPTIQQSAPRPMSSSTGHFPGAPHNTEPVTTMATSTSQPMVSPSSASYTIPQQPPGSQQGEPSSVSSQPAPSSVNPRSAPTEEPRAASSAANAPPAGDAPAADPGPAEPGANPNPGADPGAQPPADQAAGPATTSTDTTNTTTTDTTATTTTGTATTGTATTTTTTSTGTTATAVITGRITPPISLEAIFQDAIKRCNNCLFLVRKLRIKQDHVTDLYLGNKDTHEFKHAAQLYKDFGVMMQEVMSIYEKLDYIARRLPTVLPPTDSLNVMRLLYTQEHTMCHTDIFGLIEKMIDSGNWNEGNYQIFFFLSELLRVPGGRKDNRYPDLFPLPEPRFFFNATNGHMAFETAYNNMRKEIVIKSLGIYPKTLFRTSSSLIIEFLFGCGGGKVITDSDVVITIKFLVIERYGIVEYINMVAPNESWDWVNNYGTPMLNPFTPSCYEVYRRLTRQANIHLLNCFGQHASRWTSTSLLQFVSLFGKFRDVFTARCRVCRRFLKNYLPPLIFDIRTPNNAAHESCR
Length2135
PositionTail
OrganismCaenorhabditis latens
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.08
Grand average of hydropathy-0.731
Instability index56.29
Isoelectric point5.68
Molecular weight237007.21
Publications









Function






Annotated function


GO - Cellular Component
endoplasmic reticulum	GO:0005783	IEA:UniProtKB-KW
Golgi membrane	GO:0000139	IEA:UniProtKB-SubCell
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
autophagy	GO:0006914	IEA:InterPro
COPII vesicle coating	GO:0048208	IEA:InterPro
protein transport	GO:0015031	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14618
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.37|      21|      22|    1744|    1764|       1
---------------------------------------------------------------------------
 1744- 1764 (40.25/24.76)	AGPATTSTDTTNTTT.TDTTAT
 1767- 1788 (35.12/20.59)	TGTATTGTATTTTTTsTGTTAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     606.62|      74|      74|      93|     166|       2
---------------------------------------------------------------------------
   17-   53 (41.84/ 8.65)	.......................................................................PA..............Q......QQGQWD...F.I.....NLGGAP...........AP..Q....HQWnpsV.QQ........QQPQH...QQQ
   54-  111 (73.97/20.96)	NS..yyyQSAPTQQQPQ.QPHT......................NHS.........................A..............QQ.....QQ.........Y.....NVNSQH....Q......QSaeQNYQQQQW...V.AH........QQSQH...QAP
  112-  187 (131.71/43.07)	PP.....QTQQTQHQPQ.LPKP.KKAQ.............QTVIEHT.PL..L...P..............PA..............QQV....QQVAQQ...A.P.....NFTPAP....PV...L.TPsfQNVESHQQ...Y.YQ........QQPQQ...QSQ
  188-  272 (60.26/15.71)	PM.....YQQYVNSKPE.EP.....AA.............PAYYPPT.PVtqLgsaPtskevtpepqtkpaPA..............VQV....APVTQK...P.A.....APTPKP....PV...L.AP.....................paipKKEEHlsvAAP
 1309- 1348 (36.80/ 6.72)	...........TVYEPKvEP.....LQ.............PTVLVPTaPE..L...A..............P.........................................TPTP....SA...F.TA..PIPSEHQ...........................
 1389- 1468 (103.27/32.18)	PF.....SYHSTQDQYQ.HPDD.GFTT.............PPDFNDG.PL..TmasS..............PQ..............ASA....PQLAPQlaeK.P.....AAQPQP....VV...Q.AP..PPPQKHQQ...Y.SD........QQQYQ...QQP
 1469- 1579 (49.67/11.65)	P......Q.DDNQNRNQ.LNSD.NKNQsqgwlksiqtkvqKALPGQN.PM.nL...P..........edknPSivwdesqnkyvgagVEP....EPVAPP...P.P...iaSATPAP....PTgggLrAA..RGVSRYAK...VgLG........NSPSN...ASQ
 1580- 1674 (56.52/14.28)	APagmmpQAPPTASFGF.MPAPvDDDA.............DSV.D...........P..............FS..............GQAnptiQQSAPR...P.MssstgHFPGAPhntePV...T.TM....ATSTSQ.pmV.SPssasytipQQPPG...SQQ
 1690- 1739 (52.57/12.76)	NP.....RSAPT....E.EPRA...AS.............SAANAPP.AG..D...A..............PA..............ADP....GPAEPG...AnP.....NPGADP....GA...Q.PP....................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.34|      44|      55|     846|     896|       3
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  846-  879 (37.64/29.82)	.........................G.................PLKFSCPHSFLNISH..........G......GQIisiqpdQSI..SAVVF
  880-  933 (46.75/28.43)	DDIKSVL..KDIPTLqIKDaamsfkG.................PL...IPHQ..SASH..........TvrlyitKQI......ENIkrSAVAM
  940- 1005 (27.95/ 9.58)	DVVESLLvwQLLETM.VKQ.....qGnitgpdiaeilakvasqPVNIEAPPQMSNITPalnqftqfllG......GHI................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     515.62|     109|     110|     421|     529|       4
---------------------------------------------------------------------------
  317-  412 (90.67/47.93)	....KP.EESRESSS....LGG..SWATQDTEPSER.......NSVEP.VEIV..................EHPvsievDIEEKTPRVSVSENQAT.PTIVnmstslpdDRQETPEAghpNQstsvviNSSG.SP
  421-  529 (189.55/109.75)	PKEMRP.EKRSSVSSQ.GTIGTEKSRSKKNTEKSERRNYTDMFNKHEPQNHIVEKEEESGNNSD.STM.ASGRP.....DFVRGEARASYREYKKTYHAIV........DRLNFMRA...NQ......NHSDFRP
  531-  612 (101.02/54.41)	SKLANPlLAAAGLSRQhPAIRRE.SLGARN....DGRASVPLHHSHSFNDNIYS.EQNGGRRSRvSRLdSSGRP..............SSR......HA..............PGYA...SV......NHS....
  613-  700 (134.38/75.26)	..QVNPyDQRGYVQQQ.NSLFRHGRHSAMAGQYDPRRPYG...AEQYPGAVYGQEPQETSSISE.SDE.DEGES.....DY.......EIQEY.NMHH............R....QA...PS......EHS.YHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.02|      16|      18|    1912|    1927|       5
---------------------------------------------------------------------------
 1912- 1927 (30.83/20.03)	GNWNEGNYQIFFFLSE
 1933- 1948 (29.19/18.51)	GGRKDNRYPDLFPLPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.98|      10|      17|    1358|    1369|       6
---------------------------------------------------------------------------
 1358- 1369 (11.41/15.95)	QQNQfHADvRYE
 1378- 1387 (20.57/12.32)	HQEQ.HAQ.QYE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.14|      13|      15|    1821|    1833|       7
---------------------------------------------------------------------------
 1821- 1833 (22.10/15.96)	KLRIKQDHVTDLY
 1837- 1849 (23.04/17.01)	KDTHEFKHAAQLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.61|      14|      21|     775|     795|       8
---------------------------------------------------------------------------
  775-  789 (20.88/ 9.16)	RYKCDGQSEDAAlFQ
  797-  810 (20.73/16.97)	QYEARRKEKELA.YQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     208.65|      61|      64|    1042|    1104|       9
---------------------------------------------------------------------------
 1009- 1053 (56.99/31.86)	...........VE.SAMRNGLFADALVLTRR...LFPN.D..........ER.....KIEQIeSRFLQTRSMNNPV
 1054- 1116 (99.01/67.00)	TTLV.SVAKGEVP.PVLTNPPLDDHLSWRTHaaIILANLD..........QRGTALSTIHQL.GRALAKRDYHSAA
 1119- 1176 (52.65/28.81)	CFLVcGVLGGEKEnPFKPVPTPEGEEDYRRY..ISLVNSDipdneanpkcQYGFLLTDLH................
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.94|      10|      16|    1186|    1197|      10
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 1186- 1197 (12.65/15.87)	RLKpdRESLLAN
 1205- 1214 (17.29/ 9.90)	RIK..YAKLLAN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14618 with Med27 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LFWEKGLQQQDTGQPAQQQGQWDFINLGGAPAPQHQWNPSVQQQQPQHQQQNSYYYQSAPTQQQPQQPHTNHSAQQQQYNVNSQHQQSAEQNYQQQQWVAHQQSQHQAPPPQTQQTQHQPQLPKPKKAQQTVIEHTPLLPPAQQVQQVAQQAPNFTPAPPVLTPSFQNVESHQQYYQQQPQQQSQPMYQQYVNSKPEEPAAPAYYPPTPVTQLGSAPTSKEVTPEPQTKPAPAVQVAPVTQKPAAPTPKPPVLAPPAIPKKEEHLSVAAPIVIEDAKPKVTPTSSEDDWEKADMEIQRVEDENKRQKASQVAPEKPEESRESSSLGGSWATQDTEPSERNSVEPVEIVEHPVSIEVDIEEKTPRVSVSENQATPTIVNMSTSLPDDRQETPEAGHPNQSTSVVINSSGSPLEAIATSTPKEMRPEKRSSVSSQGTIGTEKSRSKKNTEKSERRNYTDMFNKHEPQNHIVEKEEESGNNSDSTMASGRPDFVRGEARAS
2) VDRLNFMRANQNHSDFRPSSKLANPLLAAAGLSRQHPAIRRESLGARNDGRASVPLHHSHSFNDNIYSEQNGGRRSRVSRLDSSGRPSSRHAPGYASVNHSQVNPYDQRGYVQQQNSLFRHGRHSAMAGQYDPRRPYGAEQYPGAVYGQEPQETSSISESDEDEGESDYEIQEYNMHHRQAPSEHSYHPSQGG
3) YGRVTPTTQATTKQEVTDANQSYGYEQHPETVYEPKVEPLQPTVLVPTAPELAPTPTPSAFTAPIPSEHQTPPEIAQQHQQNQFHADVRYEPATPTGSVHQEQHAQQYESPFSYHSTQDQYQHPDDGFTTPPDFNDGPLTMASSPQASAPQLAPQLAEKPAAQPQPVVQAPPPPQKHQQYSDQQQYQQQPPQDDNQNRNQLNSDNKNQSQGWLKSIQTKVQKALPGQNPMNLPEDKNPSIVWDESQNKYVGAGVEPEPVAPPPPIASATPAPPTGGGLRAARGVSRYAKVGLGNSPSNASQAPAGMMPQAPPTASFGFMPAPVDDDADSVDPFSGQANPTIQQSAPRPMSSSTGHFPGAPHNTEPVTTMATSTSQPMVSPSSASYTIPQQPPGSQQGEPSSVSSQPAPSSVNPRSAPTEEPRAASSAANAPPAGDAPAADPGPAEPGANPNPGADPGAQPPADQAAGPATTSTDTTNTTTTDTTATTTTGTATTGTATTTTTTSTGTTATAVIT
3
512
1279
500
704
1792










Molecular Recognition Features






MoRF SequenceStartStop




1) AIPKKEEHLSVA
2) MSLFWEKGL
3) PMYQQYV
4) WDFINLG
5) YYYQSAP
259
1
188
24
56
270
9
194
30
62