<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14610

Description Uncharacterized protein (Fragment)
SequenceLMIDENFKKRLAVSRERVEDLFYFENSKEIGRGTYGLVYKAVPKHPNGRFPNKEYALKMIEGQGFSMSACREIALFRELRHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKTKKVPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIFHLLGYPSDTDWPDMKKMPDHARLLNDARNEGTPIQTFPNSLQRYFDKWKINSQSSPYRLLVKLLTVDPTKRVSCEEAMNDIYFRKMKRPPRETDDVFNKYPIPYAKKEQQMTVPIDHVQQQQQQQQQQQQQQQQQQQQQQVQMQQPQMGPPQMMGQPQMVQPQMVQNQMGPPQMGQPQMGQPPMGGPHPGVPQDPHAHQMMQQQHHMQYQQMHDPMQGGMDEGPQAKMMRMGNVPVPRYGPMPPPYGGPQDYHNQQGPPMMQMMQQPGPSGYYGQRPGQPQVPGPGPQGYMNPQMGMQMGMRPPGVPPQAYMQQARGMPPQMGQPGPSQQQQWQQYHR
Length601
PositionKinase
OrganismCaenorhabditis latens
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.09
Grand average of hydropathy-0.814
Instability index60.00
Isoelectric point9.33
Molecular weight69663.72
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14610
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.83|      15|      18|     410|     427|       1
---------------------------------------------------------------------------
  410-  425 (32.85/ 8.38)	QMGPPQmMGQPQMVQP
  431-  445 (37.97/ 9.91)	QMGPPQ.MGQPQMGQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.06|      30|      35|     498|     532|       2
---------------------------------------------------------------------------
  446-  468 (48.57/ 8.01)	PMGGPHP.......GVPQDPHAH.......QM.MQQQH
  500-  531 (67.87/18.84)	PRYGPMP..P..PYGGPQDYHNQqgPPM.MQM.MQQPG
  534-  568 (42.62/ 7.15)	GYYGQRPgqPqvPGPGPQGYMN...PQMgMQMgMRPPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.94|      11|      15|     382|     392|       3
---------------------------------------------------------------------------
  382-  392 (23.86/ 9.25)	QQQQQQQQQQQ
  398-  408 (23.07/ 8.71)	QQQQQQVQMQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.72|      17|      37|     116|     132|       4
---------------------------------------------------------------------------
  116-  132 (31.15/17.75)	HRTAKTKKVPIM..VPRNM
  154-  172 (27.57/14.85)	HRDLKPANILLMgdGPPDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.05|      10|      35|     307|     321|       5
---------------------------------------------------------------------------
  307-  321 (16.86/18.23)	YFDKWKinsqsSPYR
  345-  354 (21.19/ 9.85)	YFRKMK.....RPPR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14610 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AMNDIYFRKMKRPPRETDDVFNKYPIPYAKKEQQMTVPIDHVQQQQQQQQQQQQQQQQQQQQQQVQMQQPQMGPPQMMGQPQMVQPQMVQNQMGPPQMGQPQMGQPPMGGPHPGVPQDPHAHQMMQQQHHMQYQQMHDPMQGGMDEGPQAKMMRMGNVPVPRYGPMPPPYGGPQDYHNQQGPPMMQMMQQPGPSGYYGQRPGQPQVPGPGPQGYMNPQMGMQMGMRPPGVPPQAYMQQARGMPPQMGQPGPSQQQQWQQYHR
340
601










Molecular Recognition Features






MoRF SequenceStartStop




1) GPSQQQQWQQYHR
2) PQAYMQQARGMPPQM
589
571
601
585