<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14578

Description "Putative mediator complex, subunit Med12"
SequenceMQRYHATNCTSAVNNSAVGGSLGRDTSRAESSAPLANIQLNRRSSQLAPYKLRCEKDSLNSRLLPPDFNPPTTNCPEETLTKDYVLGGYRQTVEGLEESREISLSQISTFTKPIILKCKEAIRKYHRAINESRAKKRKAGQVYGVPLTGNLLSKPGVFPEQKASGEDFRKKWIEGLSQQHKRLRSLADHVPHGYRKKSLLEVLIRNNVPLLRATWFIKVTYLNQVRPGSSDKTRFSCSDQWTKDVLEYLQCLLDEFVSKNNSNSTLRVKDRSPQFAYGGHMNDPEEPSLHFKWWYVVRIIQWHYAEGLLLPSLIIDWLLNQLQEKELLEILQLLLPIIYGVIETIVLSQYYVRTLVGVAVRFIQDPSPGGSDLVDNSRRAYTISALVEILRYLILAVPDTFVSLNCFPLPSCVVSNDASLITRATVEGGNNGQQQLFINSVVSSIQKCTFNLSRAAKPCHLGSNVAKAVNELDKALIHGDITIAYKCMFEDFYDQTVDKRWIADVSPHLRSTLKWIDAIESSFVCSVFFICEWATCDFRNFRTGLPRSVKFSGKRDFSQIYIAARLLEMKMKNMRSSSKSKVGVGKVKDLSHIFQSPGPLHDIVVCWLDQHQAQNGEGFKRVELLVNKLIRSGIFYPQAYVRELIVSGITGWNDTVDFNRKRRHYNLLKNLPATYIQDALQEAQIAEISLVTEAMHIYSNERRLLLRELVDHPKNVTGSNKRKDHQKLGKDQWKMSSSHASDLLSNKNVNRKIQELMDSIAILLRFPNSHSTPTMGNNVDESKRVSRSTVTSDGTPGCEECRRAKRQKVEEKSSDDEDIWWVKKGLTLKSMESFRAAEPPVKQVKQATRGRQKIVRKTSSLAQLAASRIEGSQGASTSHVCDSRVNCPHHGNDNDVPKAIDSIRTVHSDVSSIRKRMKRAPLDEKRVLVVWLMGMVRQLLDKAGKWKLGEDELSNILYLMDVCDDLVSAARLLVWLLSKVPVNPIPAVHGGRNVINVPRNVENQQCAVGENLILSSLKRYENILAVANLIPETLSAMMHRASVVLTSNGRVSGSAALFFARQMLKKYGNVASVADWIKNFKTTSDKRLIMELESGRSSDGEFGFPLGVPAGVQDFDDFLLKKISGVRISRVGLSMRDTVQRLIDEAIPVFYGQEKKPFSKKPSIEIPNDGYPIAQQVVKGLLDCMRQTGGAAQEGDPTLVAFAVSAIVTNVGQVIAKITEITPLSLSFAKHMLRVHLICLSLLKDALGERQSRVFEIALATEASSALIQVFSPPKASRGQLQLSPDSMSNENPTFSKAAKTTGAISALVIEAVLQGIASLERLVTVFRLKDGINVIQFVKSTRSNSNGNVRSIGDLKTDYLVEVSVHWFRVLIGNCRTVSDGFIVELLGESSIVALSRIQRMLPVNLVFPPAFAIFGFLVWKRFILNSNVMARDNISQLFQSLTSAVNDAIKHLPFRDVCLRESATLYDLIAADRTDFEFATMLDQSGPDLHLKMTAFVPLRARIFLNAIIDCQLPTEIMSYNDGNRNEMKLLDKLVHILDTLQPAKFHWQWVELRLLLNEQALTEKVDGRDTSFVEALSSNNENIGASENENNFIQMVLTRLLVRPDAAPLFSEVVHLLGRSLEDEVLLQAKWFLRGHDVLFGRKSIRQRLINIAESKGLSPKIQFSKPWGWCKTASDGCGGPIKKGNKRKFETVSVEEGEVIDDGIKPHSSRTFSPVSDVEAFIVSQQHVTEKALVELLLPCIDQSSDDSRVTFASDLIKQMHEIEQQISNVTHGVNKPVSSGIEGSVSKVNTRKGLRGGSPGLVRRPVGPVEMMLPSPSALRASMSLRLQLLLRLLPVICADGEPSSRSMRHTLVRVVLRLLGSRVIHEDADLSNPTCATVDLGESLFDRLLMVLHALWSTSDPCWLRPKSTPDGSRDSALFDHEVAESLQNELDGMQLPDAVRWRIQTAMPYAAISSSKFSISCQPPNVPLSVLGFLQPSVSHPGSFRNNKVSSSRATSNGPGKATKPQPESDVEIDPWNLLEDGAGSGPSSINADAIAGNDHANLKASSWLKGAVRVRRMDLTYIGAIDDDS
Length2077
PositionKinase
OrganismHelianthus annuus (Common sunflower)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Heliantheae alliance> Heliantheae> Helianthus.
Aromaticity0.07
Grand average of hydropathy-0.217
Instability index48.13
Isoelectric point9.06
Molecular weight231440.93
Publications
PubMed=28538728

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14578
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.64|      31|     120|     776|     806|       1
---------------------------------------------------------------------------
  776-  806 (56.46/43.57)	GNNVDESKRV.SRSTVTSDGTPGCEECRRA....KR
  891-  926 (44.18/32.07)	GNDNDVPKAIdSIRTVHSDVSSIRKRMKRApldeKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.50|      20|     120|     937|     978|       5
---------------------------------------------------------------------------
  725-  744 (36.34/10.11)	HQKLGK.DQWKMSSSHASDLL
  937-  957 (30.16/49.31)	RQLLDKaGKWKLGEDELSNIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.45|      40|    1546|      23|      70|      12
---------------------------------------------------------------------------
   23-   70 (64.11/53.50)	GRDTSRAES.SAPLANIQLNRRSSQLAPYKLrcekdslnSRLL.PPDFNP
 1570- 1611 (61.35/35.68)	GRDTSFVEAlSSNNENIGASENENNFIQMVL........TRLLvRPDAAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     308.79|      97|    1730|     191|     294|      13
---------------------------------------------------------------------------
  191-  294 (166.19/103.40)	PHGYRKKSLL..EVL..IRNNVPLLR....ATWFIKVTYlnQVRPGSSDKTRFSCSDQWTK.DVLEYLQCLLDEFVS.KNNSNSTLRVKDRSPqfaygGHMNDPE.EPSLHFKWW
 1916- 2023 (142.61/75.35)	PDGSRDSALFdhEVAesLQNELDGMQlpdaVRWRIQTAM..PYAAISSSKFSISCQPPNVPlSVLGFLQPSVSHPGSfRNNKVSSSRATSNGP.....GKATKPQpESDVEIDPW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14578 with Med12 domain of Kingdom Viridiplantae
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