<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14573

Description ATP-dependent DNA helicase
SequenceMAANGSTEDLLEELLNVELELQDVQDEIKRLLDKQEKLYEKQSELKAVIESYQGLEQAEKDHAAPQTENWSGAFEWDNEADDIRLNIFGIPTYRANQREIINAIMSERDVLVIMAAGGGKSLCYQLPAVLRPGIALVISPLLSLIQDQVMGLTALGIPASMLTSTTSKDNEKFVYKTLEKGEGDLKILYVTPEKVSKSKRFVSKLEKCHHAGRLSLISIDEAHCCSQWGHDFRPDYKNLGILKTQFPNVPVIALTATATKKVQLDLMEMLNIPKCIKFVSTVNRPNLFYMVREKSSVGKAVIDDIADFIQSSYTNNESGIVYCFSRKECEQVAKELRERGVSADYYHADMDVNAREKVHMRWSNSKLQVIVGTVAFGMGINKPDVRFVIHHSLGKSMETYYQESGRAGRDGLPSECLLYFRPADVPRQSSMVFYENSGLQNLYDMVQYCQSKRECRRSAFFKHFAEPLQDCNGMCDNCADLCKVKEIDASGHARALVTLLQGIQEMDQRATMLQLVEKFKVKNKEVGFELKKDELEHLVIQLIIHRVLKEEFSHTAYATNAYVTLGPLAKHVLHGKKNITLEVTSGQRSLAKSSKRSRHTGLEIKLDNLRKELSSMHGGIFPHSILSTQQISMLCSQKPESTEQLEKIIGKLKTQKYGERILEVIGKHESDDEQCDDSADEEKETSVNRNARRSKYKKVVVIDESSEDDN
Length710
PositionUnknown
OrganismHelianthus annuus (Common sunflower)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Heliantheae alliance> Heliantheae> Helianthus.
Aromaticity0.07
Grand average of hydropathy-0.432
Instability index42.67
Isoelectric point6.25
Molecular weight80280.82
Publications
PubMed=28538728

Function

Annotated function
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro
GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP14573
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     349.39|     116|     252|       9|     142|       1
---------------------------------------------------------------------------
    9-  142 (165.80/172.25)	DLLeELLNVELELQDVQdeikrLLDKQEKLY...EKQSELKAVIESYQGLEQAekdhaaPQTENWSG...AF...EWDNEADDIRLNIFGIPTYRA....NQREIINAIMSERDVLVIMaagGgkSLCYQLpAVLRPGIALVISPLL
  265-  393 (183.59/136.00)	DLM.EMLNIPKCIKFVS.....TVNRPNLFYmvrEKSSVGKAVIDDIADFIQS......SYTNNESGivyCFsrkECEQVAKELRERGVSADYYHAdmdvNAREKVHMRWSNSKLQVIV...G..TVAFGM.GINKPDVRFVIHHSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.23|      46|     445|     192|     237|       2
---------------------------------------------------------------------------
  192-  237 (84.92/56.70)	PEKVSKSKRFVSKLEKCHHAGR.LSLI............SIDEAHCCSQWGHDFRPDYK
  639-  697 (59.31/37.44)	PESTEQLEKIIGKLKTQKYGERiLEVIgkhesddeqcddSADEEKETSVNRNARRSKYK
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP14573 with Med34 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
NANANA

Molecular Recognition Features

MoRF SequenceStartStop
1) SADEEKETSVNRNARRSKYKKVVVIDESSEDDN
678
710