<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14565

Description Putative DNA helicase (RECQl4A)
SequenceMSGSNFGGGSKHVDKVTKNNWSQHAETHNNFSNQDKFLKSNFLYSLPTQKPCVEGAMAASLRSLSCQFQNATNSQSPLAEKAWQAFSNLKLSSRNYIKPGKSRPVANNNGGTAFFQDVRRPTQQYFSDVNNKKMGQNQADHSNEINNIQHSEPRPMANRFAAASTYASSSSGAGYRNMNSSYSNATNSGHCYTTNASHFKGFEETDARGIDDDDDDILLNLDVDQIVSQHYQSAGTPQSSVTPAIINNTARHDGTSLPPELCVDCTHGFKARLCPEASDHLQIMKDMLISISNDLLDNVDLNSGQIEKLRQDRLMLNKQIQQLEKYLQSRSVNDTGSKSNFASTQTTVTRAFQYESPPTLASRVDPIRLDNQFYTNNEIDGSNRWNSPSVSYSYSSAGNNNISISSAPVEREPYIPKYVEVNYIEGSNDKKWSKRDFPWTKELEDNNKKVFGNHSFRPNQREVINATMSGHDVFVLMPTGGGKSLTYQLPAFISPGITLVISPLVSLIQDQIMHLLQANIPAAYLSANMEWPEQQGILRDLCSEHCIYKLLYVTPEKVAKSDFLLRQLENLHARELLDRIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPKIPVLALTATATASVKEDVVQALGLVDCIIFRQSFNRPNLRFSVIPKTKKCLEDIDKFIRGTHFDQCGIIYCLSRMDCEKVAEKLKEYGHKAAFYHASMDPELRASVQKQWSKDEINVICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQIASCVLYYSYSDYIRVKYMLSYGAAEQTPFTYGQPRTSSTNSGRLETNSENLLRMVSYCENDIDCRRFLQLVHFGEKFDCSNCKKTCDNCSNTRTLVDKDVTMIAKQLVELVKSCKQQFSSSHILDVFRGSMSQIVKRNKHNLLSLHGAGKHIAKGEASRVLRHLVVEEILVEDVKKSDLYGSTSSVLKVNEQKAFTLLAGRQTITLRFPSTAKASKTYTSDATPAKGPLTSSKKTPVQVYTPASAQPQSTVDSGLSAKLFPALRILRRNLVKASDTGVCAHHIFADTTLHDICKRMPRNKEELLEVNGIGKAKVSKYGDKVLEVIEATIKEHYGVTRPDDIENKRNTYMNIDSYAFEGRHSLTGGNGSSANSSDSAKRRRNTVINTYDASRDDDDFVDDFVASTARSKKRVVEKPNPNPIADPVDYFDEIPDEVLDFCDSFDNVGTNVSSQKAEQNTGGRVLPSW
Length1237
PositionUnknown
OrganismHelianthus annuus (Common sunflower)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Heliantheae alliance> Heliantheae> Helianthus.
Aromaticity0.08
Grand average of hydropathy-0.543
Instability index43.81
Isoelectric point8.17
Molecular weight138222.70
Publications
PubMed=28538728

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14565
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     313.86|     101|     160|     881|     987|       1
---------------------------------------------------------------------------
  881-  987 (150.46/122.02)	ELVKSCKQQFSSSHIL.DVFRGSMSQIVKRNKHNLLSLHGAGKHIAKGEASRVLRhlVVEEILVED...VKKSDLYGSTSSVLKVnEQKAFtllAGRQTITLRFPSTAKAS
 1041- 1145 (163.41/113.05)	NLVKASDTGVCAHHIFaDTTLHDICKRMPRNKEELLEVNGIGKAKVSKYGDKVLE..VIEATIKEHygvTRPDDIENKRNTYMNI.DSYAF...EGRHSLTGGNGSSANSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.66|      44|      91|     623|     673|       2
---------------------------------------------------------------------------
  623-  673 (67.03/55.60)	ASVKEDVVQALGLVDC..IIFRQSFNRPNLRFsVIPKTkkcledIDKFIRGTH
  715-  760 (76.63/45.77)	ASVQKQWSKDEINVICatVAFGMGINKPDVRF.VIHHS......LPKSIEGYH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.65|      13|      53|      95|     107|       3
---------------------------------------------------------------------------
   95-  107 (24.73/12.24)	NYIKPGKSRPVAN
  146-  158 (25.92/13.13)	NNIQHSEPRPMAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.04|      18|     161|     227|     244|       5
---------------------------------------------------------------------------
  227-  244 (33.55/24.10)	VSQHYQSAGTPQSSVTPA
  390-  407 (31.49/22.08)	VSYSYSSAGNNNISISSA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14565 with Med34 domain of Kingdom Viridiplantae
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