<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14531

Description "Putative DNA helicase, ATP-dependent, RecQ type"
SequenceMNISMSDVEQTLVRGNGGGDANKSMRSNWCQHAKSLDNLLSRDRISKCNFLFSLTPQKQPVAEEMASTARLFTCKFQNVKTTHGPQVDKAWQALSSLKVSSRSYTSPGKSRPVAKDGDTASFQDFEPATQQCSSDANKSHTGSTLADQNLDDTDIKYSNHGLVIEPLATVPTSVAKAGRADTKNACGSDINANHLDVDQMITDSFQSISLCTPRPSISKIPPFTPAASNTITACDDKSLPEELCVECSHGFKLGVCPEAANDLKIMKDMLISISNDLLDDDGELRSDQIEKLRQDRRQLNKQIKLLEKYVTLDNEDCKSSFSAYTVTTARPLQYVTPFSARIDPVRLDDQFCTYTKTDENNNKWGTLALPCSSVGNFGDFSTPVERNYVRKYVEVNYIEGSDDVKWSNRDFPWTKKLEANNKKVFGNHSFRPNQREVINATMSRNDVFVLMPTGGGKSLTYQLPSLISPGVTIVISPLVSLIQDQIMHLLQANISAAYLSANMEWTEQQDVLRELCSGHCRYKLLYVTPEKIAKSDALLRQLENLHARELLDRIVIDEAHCVSQWGHDFRPDYQSLGILKQKFPNIPVLALTATATASVKEDVVQALGLVDCIIFRQSFNRPNLRYSVIPKTKKCVDDIDKFIKDNHNDECGIIYCLSKKDCEKVSETLQEYGHKAAFYHGSMDPDKRAAVQKMWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCVLYYSYSDYIRVKHMLSHGLLEQNYNASSGRVLETNTENLLRMVNYCENDVDCRRFLQLIHFGEKFDSFNCKKTCDNCSKAQNLVDKDVTEIAKHLVELVKSVEQQFSASHILEVYRGSLSQNVKKYEHHTLSLHGAGKSVAKGEALRVLHHLVVEEILIEVVKRSDYYGNVSSILKVNEKKASNLLAGMQTITLRFPCAVKASKSSRNDIATPAKGLTSSKQSPPRVVDTPQTQPEVDLELYAKLFSALKMLRTLLLKEAGEGVMAYHIFGNATLQHISKRIPRTKEELLEINGIGKAKVSKYGDKVLETIETTLNEYYSSNGNPKDVFDFVASPASSEKSVSKGPHTTTARRVRYLVDHDDGDA
Length1115
PositionUnknown
OrganismHelianthus annuus (Common sunflower)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Heliantheae alliance> Heliantheae> Helianthus.
Aromaticity0.07
Grand average of hydropathy-0.439
Instability index40.93
Isoelectric point7.49
Molecular weight124629.93
Publications
PubMed=28538728

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14531
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     214.99|      41|     113|     204|     244|       1
---------------------------------------------------------------------------
  156-  196 (46.61/26.20)	KYSNHGLVI.EP.LATV.PTSVAKAgrADTKNACGSDINANHLD
  204-  244 (68.63/42.12)	SFQSISLCTPRPSISKI.PPFTPAA..SNTITACDDKSLPEELC
  250-  289 (47.98/27.19)	GFK.LGVCPEAANDLKImKDMLISI..SNDLLD.DDGELRSDQI
  320-  352 (51.77/29.93)	SFSAYTVTTARP.LQYV.TPF......SARI...DPVRLDDQFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.74|      74|     188|     561|     683|       2
---------------------------------------------------------------------------
  569-  681 (90.69/158.21)	FRPD....YQSLgILKQKFpNIpVLALTAtatasvkedvvqalglvdciiFRQSFNRPNLRYSV...IPKTkkcvddidkfIKDNHnDECGiiycLSKKDCEKVSETL....QEYGH.KAAFYHG
  683-  768 (118.05/69.26)	MDPDkraaVQKM.WSKDEI.NI.ICATVA.....................FGMGINKPDVRFVIhhsLPKS..........IEGYH.QECG....RAGRDGQRSSCVLyysySDYIRvKHMLSHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.47|      58|     119|     827|     941|       3
---------------------------------------------------------------------------
  827-  890 (85.41/59.03)	CS.KAQNLVDKDVTEIAKHLVelvkSVEQqfSASHILEVYRGSLSQNVKKYEH........HTLSLHGAGKSV
  948- 1014 (85.05/129.41)	CAvKASKSSRNDIATPAKGLT....SSKQ..SPPRVVDTPQTQPEVDLELYAKlfsalkmlRTLLLKEAGEGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.51|      13|     356|     533|     555|       6
---------------------------------------------------------------------------
  512-  525 (20.99/12.77)	LRELCSGHCRyKLL
  539-  551 (22.52/12.11)	LRQLENLHAR.ELL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14531 with Med34 domain of Kingdom Viridiplantae
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