<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14490

Description "Putative mediator complex, subunit Med23"
SequenceMYKTPATSGGSNGGGIAVTTTTSVQSPHTSDIGDRSHHRSAASRASQFHPARPAIIDLFNLYLGINGRNKSDDSIREPPNKTQKRITALNIDIPPRDAQFLPDFEQLQSQFPDHEQLYTVVESVLVSLVIQCSNHGPRSKFILFAIRSLYSIGYIYWDSFLPYLLSSVTSVETSVNIFSTTSPQSDVSATSAAGPNLSNIPSPNLESSMVSANAQSCMAISSLRKLLCEIFISALESNQKPSTYADIFNKTLSWLINWDLCQNGSDEVDGVKPYKRDKALFEWLRKCLRVVRMLVEDNKCRVPFYELLRSGLHFSENLPDDVALFTLVFEVHRRRDMMAVHMQMLDQHLHCPTFGNQRLLNQAAVNTLSESNTTLRHSPITYPSVLGEPLHGEDILLTIQRGSLDWGRANRCIRHAIRNTPSPDWWRRVLVVAPCHRPNSQGSTPGAVFSSDMICEATIDRILELLKITNSGVNCWQDWLIFSDLFFFLMKSGCMDFVYFVDKLVLRLAEKDHQVLRTNHVTWLFAQIIRVELVMSALNTDSRKVETLRKLLSFHKEASSPDSDNPRSMLLDFVCSCQTLRIWSLTSSAREYLNMEQLRKAKKIDEWWRQVSKGKYMMDYMNLDDNSIGMFWVVSYTMAQPACEMVMTWLTCDGYTELPEPNPQANGTITVRREVNPVSLSLMSGFSIHLCMKLAFQMEDNMFSGVHAPNIAMVETYTRLFLIQPHSLFHPLLSHLHQKNPEILNKPGAIILVLEILNYRLFSLYRYQGKNKSLMYDVTKILSTLKGKRGEHRVCRLAENLCMNLIMSLREFFFVKKDGKGPTEFTETLNRVTVMTLAIIIKTRGISDAGHLLYLQTMLEQILANSTHTWSHKTMFYFPSVLRDALIGRTDKRPLAIQAWKQAEATVIHQCKQLLSPPDDPTYVMTYISHSFPQHRLYLCAGAWVLMRGHPEDINTGNLGRVLREFSPEEVTSNIYTMVDIILHNIQLELQQHAHSMQDVISNTCNNLAKFIWIHELLPPDILLLALTDRDDDPHALRIVVNLLERKELQQRINCYIADRGNPDHWLQNGVFKRVDLQKALGSHLSWNQKYPTYFDDIAARLFPVIPLILYRLIENDATEAADRILQIYSSFLHYYPLNFTFVRDILAYFYGHLPAKLIFRILNILDIKKVPFSQLFQERINSSEATCPPLEYFASLLLKIVNNVIPPLHISKDEGQNRNYNPTTNQSGSANNAFEPQKAFYQIQDPGTYTQLVLETAVIEILSLPVTATQIISAFVQIIVKIVKVQPNPIQSNNGFGMSPSSLYSFSDSNDASGDCGSKSNPLTIGVDFSNSVLMIQACGLLLAQLPVEFHVKLYEEASRVIKDNESHSVVAYALLDPTWAAQDNTSTALGNVVALIHAFFWNLPQQWLDNTHLLINQLRPVSSVSMLRIAFRIIGPLLPRLANAHSLFIKTLELLLSTMVDVFGKNTKPLIPVEASDITDLIDFLHHVVHYEGQGGPVQPNSKPRPDVLALCGRAIENMRPDVQRLLFHLKPNVSSIYAATKNSQNPS
Length1550
PositionTail
OrganismHelianthus annuus (Common sunflower)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Heliantheae alliance> Heliantheae> Helianthus.
Aromaticity0.09
Grand average of hydropathy-0.112
Instability index42.44
Isoelectric point7.08
Molecular weight175683.07
Publications
PubMed=28538728

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14490
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     457.00|     145|     224|     199|     354|       1
---------------------------------------------------------------------------
  199-  354 (232.48/207.59)	NIPSPN.LESSMVSA.....NAQSCM..AISSlRKLLCEIFISALESNQKPSTYAdiFNKTLSWLINWDLC....QNGSdeVDGVkpYKRDKALFEWLRKCLRVVRmlvEdNKCRVPFYELLRSGLHFSENLPDDVALFTL..VFEVHRR...RDMMAVHMQMLDQHLHCPTF
  419-  580 (224.52/163.92)	NTPSPDwWRRVLVVApchrpNSQGSTpgAVFS.SDMICEATIDRILELLKITNSG..VNCWQDWLIFSDLFfflmKSGC..MDFV..YFVDKLVLRLAEKDHQVLR...T.NHVTWLFAQIIRVELVMSALNTDSRKVETLrkLLSFHKEassPDSDNPRSMLLDFVCSCQTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.39|      16|      16|    1132|    1147|       4
---------------------------------------------------------------------------
 1132- 1147 (30.27/18.84)	FLHYYPLNFTF.VRDIL
 1150- 1166 (24.12/13.42)	FYGHLPAKLIFrILNIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.99|      47|     493|     368|     418|       5
---------------------------------------------------------------------------
  368-  418 (80.52/55.31)	LSESNTTLRHSPITY.PSVLGEPLHG..EDILLTIQrgslDWGRANRCIRHAIR
  863-  912 (77.47/44.66)	LANSTHTWSHKTMFYfPSVLRDALIGrtDKRPLAIQ....AWKQAEATVIHQCK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.64|      16|      20|    1172|    1191|       9
---------------------------------------------------------------------------
 1173- 1191 (25.40/23.56)	FSQLFQERINSseaTCPPL
 1194- 1209 (27.24/11.18)	FASLLLKIVNN...VIPPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14490 with Med23 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MYKTPATSGGSNGGGIAVTTTTSVQSPHTSDIGDRSHHRSAASRAS
1
46










Molecular Recognition Features






MoRF SequenceStartStop




1) IIDLFNLYLGING
2) MYKTPAT
55
1
67
7