<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14486

Description Putative luminal-binding protein
SequenceMARSGVALAIILIGCLSAISIAKEEANKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTESERLIGEAAKNQAAVNAERTIFDVKRLIGRKFEDKEVQRDMKLVPYKIVNKDGKPYIQVKLKDGETKVFSPEEISAMILTKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDQRIMEYFIKLIKKKHGKDISKDNRALGKLRREAERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLEKRQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAFGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTVVSIQVFEGERSLTKDCRLLGKFDLSGIAPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKAEKITITNEKGRLSQEEIERMVREAEEFAEEDKKVKEKIDARNALETYVYNMKNQISDKDKLADKLEADEKDKIEAATKEALEWLDDNQSAEKEEYDEKLKEVEAVCNPIITAVYQRTGGAAPEGGEDDEEHDEL
Length658
PositionUnknown
OrganismHelianthus annuus (Common sunflower)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Asteroideae> Heliantheae alliance> Heliantheae> Helianthus.
Aromaticity0.06
Grand average of hydropathy-0.424
Instability index29.78
Isoelectric point5.09
Molecular weight72461.42
Publications
PubMed=28538728

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14486
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      11|      27|     226|     236|       1
---------------------------------------------------------------------------
  226-  236 (20.46/10.66)	LGGGTFDVSIL
  254-  264 (21.85/11.83)	LGGEDFDQRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.69|      13|      15|     180|     194|       2
---------------------------------------------------------------------------
  180-  192 (19.48/ 6.66)	AQRQATKDAGVIA
  197-  209 (19.20/10.74)	ARIINEPTAAAIA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.01|      38|     193|     276|     317|       3
---------------------------------------------------------------------------
  276-  293 (12.75/ 6.59)	..................................GK..DISKDNRAlGKLR........REA
  294-  317 (14.60/15.53)	ERAKRAlSSQHQVRVEIESlfDGV......................................
  491-  548 (43.66/27.49)	APAPRG.TPQIEVTFEVDA..NGIlnvkaedkgtGKaeKITITNEK.GRLSqeeiermvREA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.10|      26|      27|     574|     599|       4
---------------------------------------------------------------------------
  553-  570 (18.80/ 8.00)	.......EEDKKV.KEKIDARNA.LET
  574-  599 (41.18/27.10)	NMKNQISDKDKLADKLEADEKDK.IEA
  603-  628 (36.11/22.78)	EALEWLDD.NQSAEKEEYDEKLKeVEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.17|      14|      28|      95|     108|       6
---------------------------------------------------------------------------
   95-  108 (23.64/13.23)	DVKRLIGRKFEDKE
  124-  137 (23.53/13.13)	DGKPYIQVKLKDGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.35|      25|      28|     382|     406|       7
---------------------------------------------------------------------------
  382-  406 (42.32/26.60)	GKEPNKGVNPDEA.VAFGAAVQGGIL
  411-  436 (33.03/19.13)	GDETKDILLLDVApLTLGIETVGGVM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14486 with Med37 domain of Kingdom Viridiplantae
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