<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14363

Description Uncharacterized protein
SequenceMQRYHTANCTGAVNNSIGGASARDTSRADSSSLPANFSINSRRPPPLTPYKLKCDKDPLNSRLGPPDFHPQTPNCPEETLTREYVQSGYRETVEGLEEAREISLTEVQVFTKPVVIKCREAIRKCLRAINESRAQKRKAGQVYGVPLSGALLTKPAVFPDQRACGEDFKKKWIEGLSQPHKRLRSLADHVPHGYRRKSLFEVLIRNNVPLLRATWFIKVTYLNQVRPSSASISSGTPDKTQLSRTELWTKDVIEYLQILLDEFFSRNNSHSAPHARDRSPQMLYAGSVHHRSDPAPALIDGEEPSLHFKWWYVVRLLHWHHAEGLLLPSAIIDWVLSQLQEKDILEILQLLLPIIYGVLDTIVLSQTYVRMLAGIAVRYIREPSPGGSDLVDNSRRAYTMSALIEMLRYLILAVPDTFVALDCFPLPLSILSYAVNDGSFVSKISEEARKTKDNSAGILSIFRNKGLDAQYQSFSFDQVVSSIQKRADNLAKAACPGYLVHSVAKAVQALDKSLLQGDIREAYSFLFENFCDGAVDEGWIEEVSPCLRSSLKWIGTVSLSFVCSVFFLCEWATCDFRDFRAAPPHDLKFTGRKDFSQVHIASRLLKLTIKDLQSRSRQKNDRSLGINSLAKGLGRHNNVGRVPVGNGYENKGKLKNVNRKNANSSYIFESPGPLHDIIVCWIDQHEVQKGEGLKRLQLLIVELIRSGIFYPQSYVRQLIVSGIMDASGPLGDFNRRRRHYQILKQLPGLFIRDVLEEGRIAEGSELLEAVHVYSNERRLLLRGVLCEQYQNSFKSNISMQKQKHHLASVKDGGSTSSIDQWKSIQSWSNILMSKKAKSNADIEELKTTILLLLQIPNLSTSSDTGPDESQGSVKRAAESISSKMDSVEGTPGCEDCRRAKRQKLNEEKSSCFQGHSPTSDDEDTWWMRKGPKSLDSSKVDPPLKSSKQVSKVRQKVVRKSLAQLTAARIEGSQGASTSHVCDNKVGCPHHRNGTEGETLKSVDGIRTLHGGDIVSTAKALKQLRFVQKRSITLWLVATVKQLIEETERNIANSNQFARPFGSADDRSSIRWKLGEDELSIILYLMDVCNDLVSACKLLLWLLPKVVTNPSPTIHSGRNIMMLQRNVENHVCEVGEAFLLSCLRRYENILVATDLIPEVLTAAMQRVAALLASSGRVSGSAVLNYSRYLLKKYANLPSVFEWDKSFKATCDKRLISELEPSRSLDGEFGFPLGVPAGVEDLDDFLRQKISGNRITRAGISMKDTVQRHIDDVFHYFSGKDRKFFGAGTQKSPGYEKSDDGYQIAQQITVGLLDCFRQTGGAAQEGDPSLVSSAVSAIVNNIGPTIAKMPDFTVASKHSNSSSAMASLSVARRILRIHISCLCLLKEALGERQSRVFEIALATEASSALATAFGPGKTSRSQFQLSPEDSNVNNDVLNSSARSGRVTKSAAAISALVVGAVIHGVTSLERMVTVFRLKEGLEVIQFIRSTKSYSNGNARSIPAFKVDNSIDVYVHWFRLLVGNCRTLSDGLIVELLGEPSIVALSRMQRMLPLSLVFPPAYSIFAFVIWKQIILSKDLANREDINQLYQSLTMAIGDAIKHLPFRDICLRDSQGFYDIVAADASDAEVAATLNGLDMHSKSAAFVPLRGRLFLNALVDCKMPQSLSAHDDSNRVSGLGGSKGQHSENETKLVDKLVNVLDTIQPAKFHWQWVELRLLLNEQAVVEKLEARDMSLADAIRSSSPGPEKAAASENENNFIVIILTRLLVRPDAAPLFSELVHLFGRSLEDSMLLQAKWFLGGQDVLLGRKTIRQRLINIAESKNLSTKAQFWKPWGWCRSGFDTVTNRGEKKKIEVTSLEEGEVIEDGTDTKRSGKGSTQMYNSEGFNMSQQYTTERALVELVLPCIDQGSDESRNTFASDLIKQLNNIEQQINMVTRGASKQSGSTSSGLEGPANKGSNRKVMRGGSPGMNRRNAGGAADSALPPPAALRSSMSLRLQLLLRLLPIICTDGEPSGRNMRHMLASVILRLLGNRVVHEDADLSFSPVQSSQSKMDMESLLEIVSVDLSGESLFDRMLLVLHGLLSNSQPSWLKSRSPSKLMNEFPKDSSGLDREVVESLQNDLDRMQLPGSIRWRIQAAMPVLLPSARWSVSCQLPYVPGAAVASLQPSITLSGFYSLNPSQKSPLPLARIMTSGPGKSKPLPLQQENDVEIDPWTLLEDGTGSGPSSSNAAAIGSGDQANLRASSWLKGAVRVRRTDLTYIGAVDDDS
Length2265
PositionKinase
OrganismManihot esculenta (Cassava) (Jatropha manihot)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Euphorbiaceae> Crotonoideae> Manihoteae> Manihot.
Aromaticity0.07
Grand average of hydropathy-0.270
Instability index51.60
Isoelectric point8.92
Molecular weight250594.07
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14363
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.40|      50|     448|    1171|    1295|       1
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 1203- 1253 (77.07/46.54)	KSFKATCDKRLISELEPSRSLDGEFGFPLgVPAGVEDLDDFLRQKISGNRI
 1661- 1710 (84.33/10.75)	QSLSAHDDSNRVSGLGGSKGQHSENETKL.VDKLVNVLDTIQPAKFHWQWV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.55|      17|      17|     638|     654|       2
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  638-  654 (31.18/22.25)	NVGRVPVGNGY..ENKGKL
  656-  674 (26.37/17.39)	NVNRKNANSSYifESPGPL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.63|      19|      22|      39|      59|       3
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   40-   58 (38.18/19.68)	NSR.RPPPLTPYKLKCDKDP
   60-   79 (35.45/17.46)	NSRlGPPDFHPQTPNCPEET
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.03|      18|      22|     317|     336|       4
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  317-  336 (31.30/27.62)	LHWH...HAEGLLLPsaIIDWVL
  339-  359 (24.72/14.25)	LQEKdilEILQLLLP..IIYGVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     227.39|      72|     448|    1730|    1807|       5
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 1730- 1807 (104.27/93.40)	MSLAdAIRSSSPGPEKAAASENENNFIVIILTRLLVRPDAAPLFSELVHLfGrSLEDSMLLQAKWFLGGQDVllgRKT
 2182- 2253 (123.12/85.50)	LPLA.RIMTSGPGKSKPLPLQQENDVEIDPWTLLEDGTGSGPSSSNAAAI.G.SGDQANLRASSWLKGAVRV...RRT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.03|      15|      15|     277|     291|       6
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  277-  291 (28.03/15.52)	DRSPQML..YAGSVHHR
  293-  309 (22.01/10.60)	DPAPALIdgEEPSLHFK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.16|      15|      16|     575|     590|       7
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  575-  590 (23.84/21.27)	DFRDFRAApPHDLKFT
  594-  608 (25.32/15.90)	DFSQVHIA.SRLLKLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.51|      15|      16|    2085|    2100|       8
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 2086- 2100 (26.34/18.41)	SWLKSRSPSKLMNEF
 2105- 2119 (23.17/ 8.68)	SGLDREVVESLQNDL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.96|      16|      17|     482|     497|      10
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  482-  497 (27.50/21.07)	SIQKRADNLAKAACPG
  502-  517 (24.46/17.71)	SVAKAVQALDKSLLQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     189.79|      69|     448|     682|     753|      11
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  682-  747 (101.28/66.82)	.......IDQ..HEVQKG.EGLKRLQLLIVE..LIRSGIFYPQsYV..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RQLI...VSGIMDASGP....LGDFNRRRRHYQILKQLP
  748-  789 (24.97/15.39)	GLFirDvLEE..GRIAEGsELLEAVHVYSNErrLLLRGVLCEQ.Y..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 1280- 1307 (26.45/ 9.75)	..............................................qnsfksnismqkqkhhlasvkdggstssidqwksiqswsnilmskkaksnadieelkttillllqipnlstssdtgpdesqgsvkraaesisskmdsvegtpgcedcrrakrqklneeksscfqghsptsddedtwwmrkgpksldsskvdpplksskqvskvrqkvvrkslaqltaariegsqgastshvcdnkvgcphhrngtegetlksvdgirtlhggdivstakalkqlrfvqkrsitlwlvatvkqlieeterniansnqfarpfgsaddrssirwklgedelsiilylmdvcndlvsacklllwllpkvvtnpsptihsgrnimmlqrnvenhvcevgeafllsclrryenilvatdlipevltaamqrvaallassgrvsgsavlnysryllkkyanlpsvfewdksfkatcdkrliselepsrsldgefgfplgvpagvedlddflrqkisgnritragismkdtvqrhiddvfhyfsgkdRKFF...GAGTQKSPG........YEKSDDGYQIAQQIT
 1309- 1356 (37.08/18.06)	GLL..DcFRQtgGAAQEG...........................D..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PSLVssaVSAIVNNIGPtiakMPDFTVASKH........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.44|      21|     885|    1096|    1119|      12
---------------------------------------------------------------------------
 1096- 1119 (35.40/31.46)	KLLLWLLPKVVTNPSPtihSGRNI
 1995- 2015 (41.04/26.83)	QLLLRLLPIICTDGEP...SGRNM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.31|      25|     445|    1609|    1633|      16
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 1609- 1633 (39.25/23.06)	DSQGFYDIVAADASDA....EVAATLNGL
 2051- 2079 (32.05/17.45)	DMESLLEIVSVDLSGEslfdRMLLVLHGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.44|      13|      21|     810|     822|      22
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  810-  822 (23.45/13.45)	KDGGSTSSIDQWK
  834-  846 (19.99/10.36)	KKAKSNADIEELK
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.96|      14|      19|    1529|    1542|      23
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 1529- 1542 (22.78/14.33)	LIVELLGEP..SIVAL
 1549- 1564 (21.17/12.68)	LPLSLVFPPaySIFAF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14363 with Med12 domain of Kingdom Viridiplantae
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