<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14335
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MANAETIQVSSLPLPPAQYITLYTDENIRKNRAPKPPAPMQDSYNMFGGTFSNDDNIIRPLESQGFKRLYPLHFDRRKELKKLNHSLLVNFLDLIDLLVHYPDSPRRAEKIEDLSLLFVHIHHLLNEFRPHQARETLRVMMELQKRQRIETAQRFQNHLEKVREMVKNAFASLPDLTDADRLAGGLEPMDTGESGDLAGGRGEGCHPLDRLMCEIVDMM |
Length | 219 |
Position | Middle |
Organism | Anopheles atroparvus |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae>
Anophelinae> Anopheles.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.538 |
Instability index | 48.04 |
Isoelectric point | 6.14 |
Molecular weight | 25213.63 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP14335
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 71.22| 24| 26| 63| 88| 1
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65- 88 (42.99/35.08) GFKRLYPL..HF.DRRKELKKLNH.SLL
90- 117 (28.23/14.09) NFLDLIDLlvHYpDSPRRAEKIEDlSLL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 48.06| 13| 18| 5| 17| 2
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5- 17 (23.46/13.90) ETIQVSSLPLPPA
26- 38 (24.60/14.88) ENIRKNRAPKPPA
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|