<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14318

Description BQ2448_1103 protein
SequenceMATRLGGRSHLPSSLPPTPTTSNANPNSAMPPINSHRFQPCPLDHVLRQQGLTRYHLEPPSWRPPWLPAGAGAGGGGASAASTSTSSSSSSAEPASTSIYPQFYAPCDGQEEDQLTETAVKTGFGGKNVVQTETFSAHQLIYEKLKSEDILGNLSRLSNAVRDRAQQLVPTYGPPSFKLPKRNIVTDTKREQWFTDLSNPAVPLSKLFSIVPHGYRGQQILEMFYSKKVPCSRAIWFVRAFGALEIQNNIAKRPASAPSAVASYTLEWTLIVQEFVRKQLAEIATDEPQVASSTSPTTATHPLRMSLSAKAQAKQPVMMDDDLRNAWTMKFSYTLRLLEALYEEHLLDSDSFLRFLVNQIESSNIGQLPLALFLAEEYLGEFLLSEPLSARLVAACFARLDNLSSFTTPAAIHSATMSTLTSLIRSTFVALPDAFIAAPLWSQYASSLTNLLDGLDDPVLIRTVRADLSDLKVRSEAASKGTEDEDSSEPDDIETIHLLDSIAFPALLTQVHKSLFHKRRRKRGLQVELPLMFTWATCGDRAGPYRRYAVATLIAMEKDGMEMNEQPRVDIERVFIDWIDQGARTGGARKAGDEGAEIRLLLEELIRCNVIGYSSYLQRMIARGETEEKPSIHLKLLKTVALHDESGRPLAKKRMALKSSPASRNEGEHLLGDATQELQRLVPSLVDGQSHPLAALLGDRDCTTLLGAIFGLSKDGTHLVLQRDTIPAGLARLLRPKGEHMALTAEEHAILTQTYLVVEDYFGLLQYIFVVLIHAPTRDVLSCVLDLIEGNLDCWTALDALPTLGQALLIAHEGLKVDGVNDRRLIALLRQFGQAQCLDASNLTKLEQDYQELVLQQSLPAGMPELQGLLIDSSPQAIAQLGTTLWYRYHAFENWAVIAIESGVQLLAGVSASTIVRFLREINERLPTGLEAQIGKWVAQMPSYSMIATFGAHLSSGVASLLLELVTGGILSPLALITLVILPVWKTLFVAASLPTSPASPTPIQTSSLDATLLQALDTITHIFGSLITRSSHAAAGLALNEDLSNTPAALLHRQRGDSRCANLFTQASLGELGKCVASLAVQQDFWTNLGQHDRAQATGMLLMHLNSWPAFQAAVVRDPQVFASAVLDSAPVVAVPLATSAHRPKLLAALLLTLKDSSTAIPASLVSTEDWDLFLSGLTTWRLAVSKVEVQACLERLDLDSTISDAEKAEGLNALSRHFLDRVCSGEGHTYLGEQIVKCYHGHASDELVSVAFSRLAEAVDGLARTASIERRMHSLTTLRCTGRLLNTLLQSSSASSQAAPLHQLLTAIRCCLEGLVDEGVSSPREAVLHSAHLLAIALRCSATVSPSAVQTANLFKGCLIPCTKLAAIFCRDCPNDVELSSVLLDTCSHLLFGLTDLAPSVRLPSIDSIIAPEVELDSLSEAALSRLGRLFDASGSALPVANPWDLVDHADPGPPQTTRHNSGPLDLAWFDAKIVIVIPPLIALDVHNGPPSSGATTNGNSYAVAATPFSTAAAQVHAITGHQASFERGRQSNFDFETPCIAMSVAARDHRRTLMAAKAQLSKYDPNNTGKHVLYGTAVNSPAAGTPTGSAAVPQASTATSPSVHAKNREEALAALASASASNSTKRKDPPEVVVIDSDEEDEPIAQIVAAKAPAAKRGRPSTRGGASAARKKAKT
Length1678
PositionKinase
OrganismMicrobotryum intermedium
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Microbotryomycetes> Microbotryales> Microbotryaceae> Microbotryum.
Aromaticity0.06
Grand average of hydropathy-0.032
Instability index46.49
Isoelectric point6.02
Molecular weight180963.17
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14318
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.23|      48|     277|     992|    1053|       1
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 1000- 1052 (70.89/59.05)	SPTPIQTSSL......DATLLQAL...DTITHIFGS..LITRSSHAAAGLAlneDLSntPAALL
 1347- 1405 (69.34/28.67)	SPSAVQTANLfkgcliPCTKLAAIfcrDCPNDVELSsvLLDTCSHLLFGLT...DLA..PSVRL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     218.20|      82|     511|      66|     186|       2
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   75-  186 (118.33/89.76)	G....ggasaaststssssssaepastSIYPQ.FYAPCDGQEEDQLTETAVKTgfggknvVQTETFSAHQLIYEK..LKSEDILGNLSR..LSNAVRDrAQQLVPTY..G...PPSFKLPKRNIVT
  587-  704 (99.87/40.91)	GarkagdegaeirllleelircnvigySSYLQrMIARGETEEKPSIHLKLLKT.......VALHDESGRPLAKKRmaLKSSPASRNEGEhlLGDATQE.LQRLVPSLvdGqshPLAALLGDRDCTT
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     433.50|     144|     358|     774|     973|       3
---------------------------------------------------------------------------
  396-  581 (199.26/97.52)	CFARLDNLSSFTTPAAIHSATMsTLTSLIRSTFVALPDAFIAAPlwSQYASSLTNLLDGLDDPVLIRTVRADLSDLK.VrseaaskgtededssepddietihLLDSiaFPALLTQVHKSLFHkrrRKRGLQvelplmfTWATCGDRAGPYRRYAV..ATLIAMEKdgmEMNEQPRVDIERVFIDWIDQ
  794-  940 (234.24/207.10)	CWTALDALPTLGQALLIAHEGL.KVDGVNDRRLIALLRQFGQAQ..CLDASNLTKLEQDYQELVLQQSLPAGMPELQgL........................LIDS..SPQAIAQLGTTLWY...RYHAFE.......NWAVIAIESGVQLLAGVsaSTIVRFLR...EINERLPTGLEAQIGKWVAQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.79|      26|      27|    1287|    1312|       4
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 1287- 1312 (44.57/25.75)	LNTLLQSSSASSQAAPLH..QLLT.AIRC
 1314- 1342 (36.22/19.45)	LEGLVDEGVSSPREAVLHsaHLLAiALRC
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.90|      28|     273|       8|      49|       5
---------------------------------------------------------------------------
   13-   44 (48.10/43.23)	SSLP...PTPTTSNANPNsamPPiNSHRFQPCPLD
 1438- 1468 (51.80/16.81)	SALPvanPWDLVDHADPG...PP.QTTRHNSGPLD
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.17|      26|      29|    1604|    1632|       6
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 1606- 1632 (36.22/31.99)	VHAKNREEALAALASASASnSTKRKDP
 1638- 1663 (42.95/24.48)	IDSDEEDEPIAQIVAAKAP.AAKRGRP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.37|      14|     381|      80|      94|       7
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   80-   94 (19.91/16.53)	AASTSTSSSSSSaEP
  477-  490 (25.46/16.19)	AASKGTEDEDSS.EP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.88|      25|     343|    1126|    1169|       9
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 1126- 1150 (40.67/12.34)	AVLDSAPVVAVP..LATSAHR.PKLLAA
 1470- 1497 (33.02/ 7.08)	AWFDAKIVIVIPplIALDVHNgPPSSGA
 1541- 1559 (26.19/20.43)	......PCIAMS..VAARDHR.RTLMAA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.78|      44|     700|     250|     296|      11
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  250-  296 (70.35/44.12)	IAKRPASAPSAVASYTLEwtlIVQEFVRKQLAEIA.TDEPQ.....VASS..TSP
  947-  998 (58.43/29.20)	IATFGAHLSSGVASLLLE...LVTGGILSPLALITlVILPVwktlfVAASlpTSP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.57|      28|     207|    1200|    1229|      12
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 1200- 1229 (42.87/28.45)	LDSTISDAEKAEGLN..ALSRhfLDRVCSGEG
 1408- 1437 (41.70/21.20)	IDSIIAPEVELDSLSeaALSR..LGRLFDASG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14318 with Med12 domain of Kingdom Fungi
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