<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14293

Description Uncharacterized protein
SequenceMDDELGTRKAGGRVVTVETASLDIYAKYVLRSICQQEWVGERCLKSLCEDSNDLQDPVLSSTQAQRLMQLICYPHRLLDNEEGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTANNEMNSLLENIAKATIEVFQQSAETSSASSTGNGVNNISSSASATPASNKSKPILSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSDSLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKHSAPLSWGWFGTVRVDRRVSRFEEQQRLLLYHTHLKPKPRSYYLEPLPLPPEEEEPPTPVALEPEKKAVEPSKADKTSSNPATSTEERKKKQSKTKKRNQSASKSEDFVLGPSRGVSYGVGMPTDLLHHQAGSTMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPYSGVLPSGMGSMMGIDPSYKPAVYRQQPPVSQGQILRQQLQAKLQGQGIMGQQPVRQMAPTPSYGALQPSQGYTPYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQAPMMTGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQQQQQQMLRVSGCRQEEGCWRWLTKHCLPINSTVLCPSVPSRMSAQLGTVIICQAVLPSLEVANRDRETCCAVFCWTPSMSLKERAGKLCLVFCGLHPTSSCSS
Length925
PositionKinase
OrganismColinus virginianus (Northern bobwhite) (Tetrao virginianus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Odontophoridae> Colinus.
Aromaticity0.05
Grand average of hydropathy-0.574
Instability index60.58
Isoelectric point9.12
Molecular weight102827.99
Publications
PubMed=24621616

Function

Annotated function 
ECO:0000256
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14293
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.98|      11|      16|     886|     896|       1
---------------------------------------------------------------------------
  886-  896 (23.85/16.38)	RDRET.CCAVFC
  904-  915 (16.13/ 8.71)	KERAGkLCLVFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     428.48|      79|      84|     661|     742|       2
---------------------------------------------------------------------------
  485-  552 (80.41/30.10)	.HLKPKPRSYY.LEP....LPLPPE......EEEPPTP...V.ALEPEKKAVEPSKADKTSS.N.......pATSTEERKKKQSKTKKRNQS.......
  553-  605 (62.98/22.57)	...ASKSEDFV.LGPSRGVSYGVGMpTD..LLHH..QA...GsTMSRLAYGQSP...............................VGLYAQ....NQPL
  606-  687 (86.77/38.86)	......PAGGPrLDTS..YRPVRMP.LGklVQSRPPYS...G.VL..PSGMGS.MMGIDPSY.KpavyrqqpPVSQGQILRQQLQAKLQGQGimgQQPV
  688-  749 (104.06/41.63)	RQMAPTPSYGA.LQPSQGYTPYVSH.IG..LQQHPSQS...G.TMVPPTYSGQPYQNSHPSS.N............................palVDPV
  750-  829 (94.27/37.09)	RQMQQRPSGYV.HQQAPGY....GHtLG.nTQRFPHQSiqqA.PMMTGMNHLGP.QGV.PSGiR..psqilpDQQQQQYLRQQQQQQ........QQML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     514.81|     153|     161|     158|     318|       3
---------------------------------------------------------------------------
   63-  154 (82.73/48.59)	....................................................................QA...QRLMQLIC.YP..HRLLDN.............EEGENP...QRQRI.....KRILQNLDQWtmRQSSLELQLMIKQTanneMNSLLE...NIAKATIEVFQ..QSAEtssaSSTGNGV..N
  158-  318 (240.36/183.45)	SSASATPASNkSKPILSSLERSGVWLVAPLIAKLPTSVQGHVlkaagEELEKG.QHLGSSSRKE.RDRQK...QKSMSLLSQQPFLSLVLTC.............LKGQDE...QREGLLTSlySQVQQIVTNW..REDQYQDDCKAKQL....MHEALKLRLNLVGGMFDTVQ..RSTQ....QTTEWAVLLL
  322-  481 (191.72/127.96)	SSGTVDMQSN.NELFTTVLDMLSVLINGTLAADMSSISQGSM.....EENKRAyMNLVKKLRKElGDRQSdslEKVRQLLPLPKQTRDVITCepqgslidtkgnkIAGFD.sifKKEGLQVS....TKQKISPW..DL.................FEGLKHSAPLSWGWFGTVRvdRRVS....RFEEQQRLLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14293 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GVGMPTDLLHHQAGSTMSRLAYGQSPVGLYAQNQPLPAGGPRLDTSYRPVRMPLGKLVQSRPPYSG
2) IDPSYKPAVYRQQPPVSQGQILRQQLQAKLQGQGIMGQQPVRQMAPTPSYGALQPS
3) PYVSHIGLQQHPSQSGTMVPPTYSGQPYQNSHPSSNPALVDPVRQMQQRPSGYVHQQAPGYGHTLGNTQRFPHQSIQQAPMMTGMNHLGPQGVPSGIRPSQILPDQQQQQYLRQQQ
4) SAETSSASSTGNGVNNISSSASATPASNKSK
5) SYYLEPLPLPPEEEEPPTPVALEPEKKAVEPSKADKTSSNPATSTEERKKKQSKTKKRNQSASKSEDFVLGPSRG
570
647
707
140
492
635
702
822
170
566










Molecular Recognition Features






MoRF SequenceStartStop




NANANA