<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14280

Description Uncharacterized protein
SequenceMPLCDERLPSFCSFQDESSSHECNQRMILLYGVGKERDEARHQLKKITKDILKILNKKSTTESGVGDEGQKARKNKQEAFPTLETVFTKLQQLSYFDQHQVTSQISSNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLLDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHACLILNSEQTAQVFEGSVAARFPFGFRWLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYSNVQPSNSNLLWDPEFMLDFIENPSAHSINYSMLGKILSDNAANRYSFVCNALMNVCMGHQDAGRINDIANLCAELTACCTVLSSEWLGVVKALCCSSNHVWGFNDLLCSVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDPDAEPGARMTCRLLLHLFRTPQVCLFPQGAGKLFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAILMLGDAEIGSSSVTATKSEELPVGGRLDEPPGDEVWGSSHALNSRGKAVSIETASLSEYARYVLRTICQQEWVGEHCLKEPERLCTDKDLILDPVLSNKQAQKLLQLICYPHGVKECSEGENPQRQHIKRILQNLDQWTLRQSWLELQLMIKQCMKEPGSGSVAEMNSLLDNIAKATIEVFQQSADLNNNSSNSGIGLFNPNSVGNADTSNTRQNGKKTFLSSSEWRGVWLVAPLIAKLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQGDVKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMQTNKSLARWQFLKVTFCNFTPSELFTTVLDMLGVLINGTLASDLSSASQGGPEENKRAYMNLVKKLKKELGDKRSDSIDKVRQLLPLPKQTCDIITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGHKNPAPLSWAWFGTVRVDRKVIKYEEQQHLLLYHAHPKPKPRSYYLEPLPLPPEEEEEEPTTPVSQEPERKSGELSDQGKHAMDDEKKTKGRKRKSKSSSKADDVSSSAASLQDGFDNIMGQPMDPAALFTPQVRPVPQLPQYPGLQQAQSMPHGYTMYSTPMPLQQQQQPGSVVLSPGYTPRAYTAHSSPALMERLRPGQPGSVAQQQAAAYIQPLAGTPRLTHQPLQPNSLIGAGLDSASTTRTHPNLSSAQLPQEQMRQRQQQLRQQRLFQLSAADNAELEHQEDHTPWDPVLGASPGPSPHTGHENVVLS
Length1326
PositionKinase
OrganismColinus virginianus (Northern bobwhite) (Tetrao virginianus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Odontophoridae> Colinus.
Aromaticity0.06
Grand average of hydropathy-0.348
Instability index52.36
Isoelectric point6.49
Molecular weight146931.62
Publications
PubMed=24621616

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14280
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.83|      25|      27|    1148|    1174|       1
---------------------------------------------------------------------------
 1150- 1174 (50.04/24.21)	P.QL.PQYPG..LQQAQSMPHGYTMYSTP
 1176- 1203 (35.10/10.73)	PlQQ.QQQPGsvVLSPGYTPRAYTAHSSP
 1208- 1233 (26.70/ 8.25)	..RLrPGQPG.sVAQQQAAAYIQPLAGTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.29|      12|      29|      32|      43|       2
---------------------------------------------------------------------------
   32-   43 (22.36/13.18)	GVGKERDEARHQ
   64-   75 (21.93/12.79)	GVGDEGQKARKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     599.86|     160|     218|     515|     716|       3
---------------------------------------------------------------------------
  296-  357 (32.93/12.62)	.....................................................................................................................ENPSAHSINySMLGK.....IlsDNAANRYSFVCNALM.NVCMGHQDAGRINDIANLCAELtACCTV..........................................L
  361-  513 (181.11/105.35)	WLG..VVKAL.CCSSNHVWGFNDLLCSVDvSDLSFHD.SLATFIAILIARQCfSLEDVVQH.VALPSLLaaaCGDPD...AEPGARMTCRLLLHLfrtpqVClFP..QGAGKLFPGiRSSCDRHLL.AAAHN.....S..IEVGAVFAVLKAILMLGD..AEIGSSSVTATKS......................................................
  515-  716 (237.93/233.20)	ELP..VGGRLDEPPGDEVWGSSHALNSRG.KAVSIETaSLSEYARYVLRTIC.QQEWVGEHcLKEPERL...CTDKDlilDPVLSNKQAQKLLQL.....IC.YP..HGVKECSEG.ENPQRQHIK.RILQN.....L..DQWTLRQSWLELQLMIKQCMKEPGSGSVAEMNSLLDNI.AKATIevfQQSADlnnnssnsgiglfnpnsvgnadtsntrqngkktfL
  733-  855 (147.88/83.41)	KLPtsVQGRVLKAAGEELEKGQH.LGSSS.K....................................K......ERD.........RQKQKSMSL.....LSqQPflSLVLTCLKG.QDEQREGLL.TSLQNqvnqiL..SNW..REERYQGDVKARQMMHEALQLRLNLVGGMFDTV.QRST....QWTTD...................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.12|      11|      30|     231|     243|       4
---------------------------------------------------------------------------
  231-  243 (17.92/15.71)	SECSSPERCIlaY
  264-  274 (20.20/10.76)	SACSKVKQTI..Y
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.63|      11|      29|     162|     172|       5
---------------------------------------------------------------------------
  162-  172 (16.60/10.37)	AELLLKSSSLA
  192-  202 (19.03/13.12)	ACLILNSEQTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.89|      35|     103|     956|     995|       6
---------------------------------------------------------------------------
  956-  995 (53.24/50.75)	LPLPKQTCDI.....ITCEP...MGSLIDtKGNKiaGFDsiDKKQARG
 1061- 1103 (51.65/32.38)	LPLPPEEEEEepttpVSQEPerkSGELSD.QGKH..AMD..DEKKTKG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.02|      11|      30|     686|     696|       7
---------------------------------------------------------------------------
  686-  696 (20.90/14.15)	SSNS..GIGLFNP
  717-  729 (16.12/ 8.93)	SSSEwrGVWLVAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14280 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RSYYLEPLPLPPEEEEEEPTTPVSQEPERKSGELSDQGKHAMDDEKKTKGRKRKSKSSSKADDVSSSAASLQDGFDNIMGQPMDPAALFTPQVRPVPQLPQYPGLQQAQSMPHGYTMYSTPMPLQQQQQPGSVVLSPGYTPRAYTAHSSPALMERLRPGQPGSVAQQQAAAYIQPLAGTPRLTHQPLQPNSLIGAGLDSASTTRTHPNLSSAQLPQEQMRQRQQQLRQQRLFQLSAADNAELEHQEDHTPWDPVLGASPGPSPHTGHENVVLS
1054
1326










Molecular Recognition Features






MoRF SequenceStartStop




1) SYYLEPLPLP
2) YTPRAY
1055
1192
1064
1197