<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14241

Description Uncharacterized protein
SequenceMRSVSVGLCHQQCSPEDGGFGQDESSSHECNQRMILLYGVGKERDEARHQLKKITKDILKILNKKSTTESGVGDEGQKARKNKQEAFPTLETVFTKLQQLSYFDQHQVTSQISSNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLLDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHACLILNSEQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYSNVQPSNSNLLWDPEFMLDFIENPSAHSINYSMLGKILSDNAANRYSFVCNALMNVCMGHQDAGRINDIANLCAELTACCTVLSSEWLGVVKALCCSSNHVWGFNDLLCSVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAGKLFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAILMLGDAEIGSSSVTAARSEELQVGGRLDEPPGDEVWGSSHALNSRGKAVSIETASLSEYARYVLRTICQQEWVGEHCLKEPERLCTDKDLILDPVLSNKQAQKLLQLICYPHGVKECSEGENPQRQHIKRILQNLDQWTLRQSWLELQLMIKQCMKEPGSGSVAEMNSLLDNIAKATIEVFQQSADLNNNSSNSGIGLFNPNSVGNADTSNTRQNGKKTFLSSSEWRGVWLVAPLIAKLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQGDVKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMQTNKWQFLKVTFCNFTPSELFTTVLDMLGVLINGTLASDLSSASQGGPEENKRAYMNLVKKLKKELGDKRSDSIDKVRQLLPLPKQTCDIITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGHKNPAPLSWAWFGTVRVDRKVIKYEEQQHLLLYHAHPKPKPRSYYLEPLPLPPEEEEEEPTTPVSQEPEGKSGELSDQGKHAMDDEKKTKGRKRKSKSSSKADEYPQNSLYRVPPNYSPVPSHMMQHPQPALWGYTVMGQPQQPGFFVQNQPLPPGSSRLDPTSSFVPANTKQALSNMLQRRSGTVLQPPSLHAITPQQQLLQMKLLQQEQQQRLLRHQAQARSLQQDVSSSAASLQDGFDNIMGQPMDPAALFTPQVRPAPQLPQYPGLQQAQSMPHGYTMYSTPMPLQQQQQPGSVVLSPGYTPRTYTAHSSPALMERLRPGQPGSVAQQQAAAYIQPLAGTPRLTHQPLQPNSLIGAGLDSASTTRTHPNLSSAQLPQEQMRQRQQQLRQQRLFQMQQGQQQQTLDLQPVQPQQPLQFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQGVNQYGHPPHF
Length1432
PositionKinase
OrganismCallipepla squamata (Scaled quail)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Odontophoridae> Callipepla.
Aromaticity0.06
Grand average of hydropathy-0.440
Instability index57.73
Isoelectric point7.69
Molecular weight159253.24
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP14241
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     192.10|      25|      26|    1229|    1253|       1
---------------------------------------------------------------------------
 1108- 1130 (33.79/13.10)	G...Q.P.QQP.GF......FVQNQP...LPPG..SSRLD
 1166- 1193 (28.11/ 9.55)	P...Q.Q.QLL.QMK..L..LQQEQQqrlLRHQ..AQARS
 1229- 1253 (49.35/22.83)	P...A.P.QLP.QYP..G..LQQAQS...MPHG..YTMYS
 1255- 1282 (29.63/10.51)	P...M.PlQQQ.QQP..GsvVLSPGY...TPRT..YTAHS
 1341- 1370 (24.24/ 7.13)	PnlsS.A.QLP.QEQ..M..RQRQQQ...LRQQrlFQMQQ
 1381- 1409 (26.97/ 8.84)	P...VqP.QQPlQFPrqG..LQQTQQ...QQQT..AALVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.71|      18|      27|     169|     187|       2
---------------------------------------------------------------------------
  169-  187 (26.66/23.09)	AELLLKSSSLAGSYtTGLC
  199-  216 (33.05/23.38)	ACLILNSEQTAQVF.EGLC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.85|      20|      37|     899|     935|       3
---------------------------------------------------------------------------
  899-  919 (31.99/46.62)	GDKRS..DSIDKvRQLLPLPKQT
  936-  957 (29.86/ 7.40)	GNKIAgfDSIDK.KQARGLQVST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.57|      15|      35|     326|     342|       4
---------------------------------------------------------------------------
  326-  342 (25.31/18.83)	CMGHQDAGRINDIanLC
  364-  378 (32.26/17.86)	CCSSNHVWGFNDL..LC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.54|      23|      40|     516|     539|       5
---------------------------------------------------------------------------
  516-  539 (39.32/34.41)	ARYVLRTICQQEWVGEhCL..KEPER
  557-  581 (35.23/23.92)	AQKLLQLICYPHGVKE.CSegENPQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     203.02|      65|     189|     426|     492|       6
---------------------------------------------------------------------------
  426-  492 (105.85/72.26)	PGIRSSCDRHLL..AAAHNSIEVGAVFAVLKAilMLGDAEIG...SSSVTAARSEELQVGGR...LDEPPGDEVW
  614-  686 (97.18/60.59)	PGSGSVAEMNSLldNIAKATIEVFQQSADLNN..NSSNSGIGlfnPNSVGNADTSNTRQNGKktfLSSSEWRGVW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.27|      16|     119|     960|     984|       7
---------------------------------------------------------------------------
  960-  978 (25.03/28.48)	KVSpwdLFEGHKNPAPLSW
  998- 1013 (31.23/10.12)	HLL...LYHAHPKPKPRSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.27|      24|     170|    1137|    1160|       8
---------------------------------------------------------------------------
 1137- 1160 (44.12/26.64)	P.ANTKQALSNMLQRRS..GTVLQPPS
 1309- 1335 (33.15/17.91)	PlAGTPRLTHQPLQPNSliGAGLDSAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.45|      24|     180|     588|     613|       9
---------------------------------------------------------------------------
  588-  613 (40.67/28.75)	LQN.....LDQWtlRQSWLELQLMIKQCMKE
  736-  754 (23.77/10.00)	........LSQ....QPFLSLVLTCLKGQDE
  763-  791 (34.01/17.60)	LQNqvnqiLSNW..REERYQGDVKARQMMHE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.29|      12|      30|      39|      50|      10
---------------------------------------------------------------------------
   39-   50 (22.36/14.54)	GVGKERDEARHQ
   71-   82 (21.93/14.11)	GVGDEGQKARKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.04|      10|     126|    1093|    1106|      13
---------------------------------------------------------------------------
 1073- 1082 (19.60/ 7.55)	EYPQNSL..YRV
 1095- 1106 (15.44/12.97)	QHPQPALwgYTV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14241 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PQQQLLQMKLLQQEQQQRLLRHQAQARSLQQDVSSSAASLQDGFDNIMGQPMDPAALFTPQVRPAPQLPQYPGLQQAQSMPHGYTMYSTPMPLQQQQQPGSVVLSPGYTPRTYTAHSSPALMERLRPGQPGSVAQQQAAAYIQPLAGTPRLTHQPLQPNSLIGAGLDSASTTRTHPNLSSAQLPQEQMRQRQQQLRQQRLFQMQQGQQQQTLDLQPVQPQQPLQFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQGVNQYGHPPHF
2) QPGFFVQNQPLPPGSSRLDPTSSFVPANTKQALSNMLQRRSGTVLQPPSLHAI
3) RSYYLEPLPLPPEEEEEEPTTPVSQEPEGKSGELSDQGKHAMDDEKKTKGRKRKSKSSSKADEYPQNSLYRVPPNYSPVPSHMMQHPQPALWGYTVMGQP
1166
1112
1011
1432
1164
1110










Molecular Recognition Features






MoRF SequenceStartStop




1) PRSYYLEPLPLPPEE
1010
1024