<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14230

Description Mediator of RNA polymerase II transcription subunit 27
SequenceMMAHHPPHPVGGIPMNPGGGVGGVGSMLPTPTTGEGQGSVEMLQKALDAVKMLRCNVTAFFETIATGPKLESNSSTTTQEERERAFKSVFTVFMQRMVDNVKEMDANISGMTQPSPGPFNLGNSSFVNQEVAPERIPLYSQLVDSYKWMEKVHEYSGVASPILSQNSMKRTYYNTSLSAKRRRTLINNYVVAPEAVNSTINGIANSYNDMKIIITRPLGTNAALNITLGRTLTAVIVLKGWLIEWVVIRGVLEEMMKEDGTLDFWSESRYKVFQKVTDNANAAMLHFCAPTHPELSVKSFMTWLHSYITLFTQPCKKCGLHLNNNLPPTWRDLRSLEPYHEECKP
Length345
PositionTail
OrganismFolsomia candida (Springtail)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Collembola> Entomobryomorpha> Isotomoidea> Isotomidae> Proisotominae> Folsomia.
Aromaticity0.08
Grand average of hydropathy-0.268
Instability index37.60
Isoelectric point8.20
Molecular weight38462.77
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14230
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      98.09|      23|      59|     128|     150|       1
---------------------------------------------------------------------------
   79-  105 (18.90/11.88)	.QE.ERERafksvF.TVFMQrMVDNVKEMD
  128-  150 (41.86/36.30)	NQEVAPER.....I.PLYSQ.LVDSYKWME
  174-  189 (17.06/ 9.92)	NTSLSAKR.........RRT.LINNY....
  191-  211 (20.28/13.34)	...VAPEA.....VnSTING.IANSYNDMK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14230 with Med27 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MMAHHPPHPVGGIPMNPGGGVGGVGSMLPTPTTGEGQGSVEML
1
43










Molecular Recognition Features






MoRF SequenceStartStop




NANANA