<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14229

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMVMQSKELILSRDAQAKNIIMRAWRERWTVMQWGINVRTLISSCAVLKSVCKYDGFHKPYCVASLLDLLNNIKERVILNENEDLEQCMELSQSLALTTHWLLTCMYSSLENLSDLSINDFPVDVEDSKIVIKCRKLLEYFLTNPFISGLINCAVLENDEMFQNIKKMSGEIAKFADGHHHQDIAFITGLIEQIGERRGDCISSRSILTLSRSIDGRQTLIGSPSILTTIISAALFRSSENVADIANELQIIKNLRGLTNVELFNEIMHAAVVSLVDCLGKPNELQILGFVFLVLPSLLKSLVLILDASNDDFCNGLCLFLDNDSVLSITDTKLACYTLDIFLVSFQKLNIISDGDRKQILEKKPRRSLQTDHSSNNAVLLLETEKTLQHIFNALDGVSDFEKNKDAILGTLYDVICNNFEFVLTTTSCTNKLKQLSSKLLKLNQYSLQAVGENGKTSATRAMIFDITFLMLCSIGQTYGVEALASDESDYFFVEWYNECMVENNSVKNPDAILNRCNQNKVEILINTFLQGESELKTSLVFWNELCTNVVGVIRDMVFAWEAESANFADVKKVLDVIRSKMSPENQSGKARYILNHFLSNLNVSNDEEHFQERFAVMNKVISKMINCVQPTSGASSPISTGNCTIESKPMSDLYKKCFSSMQSRGLIDIDTMISLQSLLDLNGLHYFVQGLITEMMENQSPADLLQWCDMLYGLFKNNLFECTAALLGVVIPSLLHYWDRDSNFVEPQILALVSLTVDCILSCYLQGETIKTLEDSDDEPSLCKRRKISDPKDSKKMETLENLKYMLRELYEELDKILKATSDARPQGIFVLRFLEQLSIKASDPTIFSSLPHSVITNLMSLMSDDINPQMLLGWHSLNEKTGRANCILTICNLMKMQNVNRHCCDSSSD
Length910
PositionTail
OrganismFolsomia candida (Springtail)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Collembola> Entomobryomorpha> Isotomoidea> Isotomidae> Proisotominae> Folsomia.
Aromaticity0.07
Grand average of hydropathy-0.019
Instability index48.50
Isoelectric point5.08
Molecular weight102650.21
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14229
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     209.33|      67|     177|     541|     613|       1
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  541-  613 (104.34/79.24)	FWNEL..CT.NVVG.VIRDMVFAWEAESaNFADvKKVLDVIrskmSPENQSGKARYILNHFLSNLNVSNDEEHFQER
  715-  785 (104.98/63.11)	FKNNLfeCTaALLGvVIPSLLHYWDRDS.NFVE.PQILALV....SLTVDCILSCYLQGETIKTLEDSDDEPSLCKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.54|      12|     102|     402|     418|       2
---------------------------------------------------------------------------
  402-  418 (17.81/26.12)	KNKDAILGTlydviCNN
  507-  518 (24.72/17.33)	KNPDAILNR.....CNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     141.89|      45|     178|      35|      79|       3
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   35-   79 (78.06/42.88)	INVR.TLISSCAVLKSVCKYDGFHKPYCVASLLDLLNNIKE.RVILN
  213-  259 (63.83/33.91)	IDGRqTLIGSPSILTTIISAALFRSSENVADIANELQIIKNlRGLTN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14229 with Med24 domain of Kingdom Metazoa
Unable to open file!