<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14227

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMELLYEVEPDLDGAEDYVVSTKRMKLTPERRPTIAISVHNLLAFSSNVDLSQCQSSSSSPMKDGGPPEVGKRSTYTASASSNISDDVGIAGCHLYVTDLNTPWEIFLIKNSSAQIRYLQWDHAGTKLCVGTDDGRVEIYVMVDNLLNKWGVSYEAALPGEPILIAEWLNAPRKVTVNPEKMDSMVYSEKYLTSVPFSSRGFGGKALDGLVVVTATGLLGAVVQSNSEETGGKPIVASEKMFAMRNHIVHADLAYSTDGDILVVTSTENMKQPVLVNKINVSLSHSRDKVEIKAVPCQSLFLQSMLDHSISSVKFINKCDTDHLLISLTNRLTGSSMLYIYELVAHTVTLKSKFNQSSAAISTGSDVVNTFRWQQTSHIQFGSSISSICSLPSPLIPNINSSISPTTTTTSSSSGSSSSMQNQNQQTATVLTPIIATALSNGCIVLSRCDNLQQICSYSTTSSTPSSGHPFAIGGVKLERDHNTDWNSSPTKKKECSSPSKINSGSSSPGTENPVSISFTWSGSILVSLTENSHLKTYKVHANLDASTAALLMELSMMGGLDPWDVMMCIRTNLIDNITDRLSETFARQPPPVQTHYNGRMLVIKAGLYRIGSSGTARINDQQTLLVLYLVSGALKALLRPAELSSREKGPAESLASLLSSSGEHDLTKVLVQMAATEYAVEANTLQSLQQILQWCADLALKLLSTLPDLRHSRAPGWEVCRDSKAVGTLRELIVLMRIWGLQRPSCLPAFRKTSENLDVLPLLFRLLTRLSVAPHDPDEALIGEAALLMYSLIYLFKT
Length798
PositionTail
OrganismFolsomia candida (Springtail)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Collembola> Entomobryomorpha> Isotomoidea> Isotomidae> Proisotominae> Folsomia.
Aromaticity0.06
Grand average of hydropathy-0.072
Instability index45.89
Isoelectric point6.24
Molecular weight86794.02
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
catalytic activity	GO:0003824	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14227
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     209.46|      42|      52|     373|     414|       1
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  333-  365 (37.55/12.99)	...........GSSMLYI..YELVAHTV.TLKS.KFNQ.SSAAISTG...SD
  373-  414 (72.08/30.22)	QQTSHIQ...FGSSISSI..CSLPSPLIPNINS.SISP.TTTTTSSS...SG
  424-  467 (55.90/22.15)	QQTATVLtpiIATALSNG..CIVLS.RCDNLQQ.ICSY.STTSSTPS...SG
  478-  522 (43.93/16.17)	ERDHNTD...WNSSPTKKkeCSSPS....KINSgSSSPgTENPVSISftwSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     180.10|      58|     240|       7|      69|       2
---------------------------------------------------------------------------
    7-   69 (95.78/70.20)	VEPDL....DGAEDYVVSTKRMKltperRPTIAISVHNLLAFSSN.VDLS..QCQSSSSSPMKDGGPPEV
  248-  312 (84.32/51.51)	VHADLaystDGDILVVTSTENMK.....QPVLVNKINVSLSHSRDkVEIKavPCQSLFLQSMLDHSISSV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14227 with Med16 domain of Kingdom Metazoa
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