Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADGQRALTAAFPPPPPFWKHFTPDNIDKLDKIKKESSQQSEQGDIFEKKWLPSELRALDVPPELRYLIPPEAPIEGSYSVFGELQNLSTNLPSLKEQGIEQLYPDPPTSDATKDDQNGGQPLNHAYYLLKISKSLLLNFLEFVGVLSIAPEEFEAKLEDLRNLFINAHHLLNLYRPHQARESLILMMEEQLESTRNQIQEMDDVKNRVERLLEQLTAEGLDAQQSISLESSDEAKSVEFDSKTVEEARQLWDLLKDEQE |
Length | 260 |
Position | Middle |
Organism | Talaromyces atroroseus |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Talaromyces> Talaromyces sect. Trachyspermi. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.640 |
Instability index | 53.60 |
Isoelectric point | 4.59 |
Molecular weight | 29741.01 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP14216 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 34.99| 10| 33| 154| 163| 1 --------------------------------------------------------------------------- 154- 163 (17.23/11.59) FEAKLEDLRN 188- 197 (17.77/12.17) MEEQLESTRN --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 107.01| 26| 34| 46| 71| 2 --------------------------------------------------------------------------- 18- 38 (25.05/11.32) .F.WKHFTPDNIDKL.DkIKKE.....SS 46- 71 (46.70/26.80) IF.EKKWLPSELRAL.D.VPPELRYLIPP 81- 108 (35.26/18.62) VFgELQNLSTNLPSLkE.QGIEQLYPDPP --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) ELRYLIP 2) GDIFEKKWL 3) HFTPDNIDKLDKIKKESS | 64 44 21 | 70 52 38 |
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