<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14185

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMAIPMVPMETQLQSIFEEVVKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKLHHEFLQQSLRNKNLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRTPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTSENEIITHFSAQGSSPLFLCLLWKMLLDTDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEGHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNPREENPWVPDDAYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDCIVNVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEALIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADRYSSHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMEPAAVSQQPLSSGSPAQQPSQVPVNVALPVTQ
Length1377
PositionTail
OrganismLonchura striata domestica (Bengalese finch)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Passeroidea> Estrildidae> Estrildinae> Lonchura.
Aromaticity0.10
Grand average of hydropathy-0.020
Instability index45.23
Isoelectric point7.09
Molecular weight157537.33
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14185
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.92|      31|     674|     404|     435|       5
---------------------------------------------------------------------------
  404-  435 (53.64/44.75)	KLFDLLyPEKEYIPVPDI....NK.PQ.STHAFAMTCI
 1081- 1117 (45.28/31.13)	RLVDTM.AGKSPGPFPNCdwrfNEfPNpAAHALHVTCV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.94|      34|     619|     214|     255|       7
---------------------------------------------------------------------------
  214-  255 (45.93/57.87)	DF.VDTFRPTARINSIcGRCslLPVVNNsgaMCnsWKLDPTTL
  835-  869 (58.01/39.49)	DFlVYEFSTSAGGQQL.NKC..IEILND...MV..WKYNIVTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.49|      16|     674|      45|      62|      11
---------------------------------------------------------------------------
   45-   62 (23.66/18.87)	ISCLGA.....FRQfwSSLSQES
  739-  759 (23.83/10.69)	LSCFPAplqvfFKQ..NNVPQES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      32|     346|     355|      16
---------------------------------------------------------------------------
  346-  355 (18.69/13.38)	IFFVLFQFAS
  379-  388 (19.45/14.32)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.51|      16|      19|    1002|    1017|      18
---------------------------------------------------------------------------
 1002- 1017 (32.07/21.07)	YKFHDRPVTYLYNTL.H
 1019- 1035 (23.44/13.35)	YEGHLRERTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     175.90|      55|     861|     271|     325|      21
---------------------------------------------------------------------------
  271-  325 (98.39/65.58)	EPQTALLRYVLE.QP.YSRDMVC...NMLGL..NKQHKQRCPVLEDQLVDLVVYAMERSETE
 1128- 1189 (77.51/50.04)	EVGNALLNVVLKsQPlVPRENITawmNAIGLiiTALPEPYWIVLHDCIVNVINSPSLTSETE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.30|      19|     783|      89|     109|      23
---------------------------------------------------------------------------
   89-  109 (31.47/25.06)	CLAMAVETGllPPRMVCESLI
  875-  893 (36.83/23.01)	CLAMRSHEG..NEAQVCYFII
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14185 with Med23 domain of Kingdom Metazoa
Unable to open file!