<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14170

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKRFFPRGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLMAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECISLCRALLSALTWLLRCATFYAEKVKEPLEQAAAENQLKMCLERLEKMLSSTKNRALIHIAKLEETSSWSTVEQSLIKLGENLNNLGSSPLRSQADDCVSLIKSIPTMLSVHSEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIECPEGTEELKWTAFTFLKMPQVLVKLKKYPQGDKDFTEDVNSAFEFLLKLTPLLDKADQRCNCNCMSLLLQECSKQGLLSEANMNNLIDKRAADKENSPSLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFVKLNEFTKQITGEISKSGPVRALLFDISFLMLCHVAQTYGSEVILSDSNPPGEVPFFETWMLTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEVCLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYGENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTSVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLTLLGHILPNLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHSKVQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDSNILSSPNRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVECLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length986
PositionTail
OrganismLonchura striata domestica (Bengalese finch)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Passeroidea> Estrildidae> Estrildinae> Lonchura.
Aromaticity0.07
Grand average of hydropathy0.005
Instability index49.10
Isoelectric point6.72
Molecular weight110478.81
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:Ensembl

GO - Biological Function
GO - Biological Process
stem cell population maintenance	GO:0019827	IEA:Ensembl
transcription by RNA polymerase II	GO:0006366	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14170
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.23|      23|      38|     368|     390|       1
---------------------------------------------------------------------------
  368-  390 (39.19/27.76)	GLL..SEANMNNLIDKRAADKENSP
  405-  429 (34.04/23.07)	GLIlrAEPTVTNILKTMDADHSKSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     393.42|     126|     300|     514|     640|       2
---------------------------------------------------------------------------
  514-  640 (215.27/141.36)	NPPGE.VPFFETW.MLTCMPEEGKILNPDH.............PCFRPDSTKVESLVALL.NNSSEMKLVQMKWHEVCLSISAAILEILNAWE..NGVLTfESIQKITDNIKGKVCSMAVCAVAWLVAH.VRMLGLDEREKSLQMI
  800-  944 (178.14/111.90)	DPPGKaLAKLSVWcALSSYSSHSKVQASARqkkrhrediedyiSLFPLDDTQPSKLMRLLsSNEEDSNILSSPNRSMSSSLSASQLHTVSMRDplNRVLA.NLFLLISSILGAKTAGTHTQFVQWFMEEcVECLEQGSRGSILQFM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.36|      43|     300|     124|     171|       3
---------------------------------------------------------------------------
  124-  171 (62.83/56.00)	LLSALTWLLRcatfyAEKVKEPLEQAAAENQLKMCLERLEKMLSSTKN
  432-  474 (66.53/45.02)	LLGVLGHMLS.....GKSLDLLLAAAAATGKLKSFARKFVKLNEFTKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.43|      35|     182|      79|     116|       7
---------------------------------------------------------------------------
   79-  116 (58.73/40.92)	LMAISKFDDFSRDLCVqslLEI.MDMFCDRLSCHGKAEE
  264-  299 (58.70/33.86)	LMMVKRMQRIPSPLFV...LEIwKACFVGLIECPEGTEE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14170 with Med24 domain of Kingdom Metazoa
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