Description | Mediator of RNA polymerase II transcription subunit 21 |
Sequence | MADRLTQLQDAVNSLADQFCNAIGVLQQCGPPASFSNIQTAINKDQGVNPTEEYAQLFAALIARTAKDIDVLIDSLPSEESTAALQAASLYRLEEENHEAAARLEEVVYRGDVLLEKIQSALADIAQSQLKTRSGTHSQPLPDS |
Length | 144 |
Position | Middle |
Organism | Lonchura striata domestica (Bengalese finch) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Passeriformes> Passeroidea> Estrildidae> Estrildinae> Lonchura. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.249 |
Instability index | 54.64 |
Isoelectric point | 4.40 |
Molecular weight | 15568.14 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process | stem cell population maintenance GO:0019827 IEA:Ensembl |
Binary Interactions |
Repeats | >MDP14167 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) PTEEYAQLFAALIARTAKDIDVLIDSLPS 2) TAALQAASLYRLEE | 50 82 | 78 95 |
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