<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14159

Description KDM4 protein
SequenceMATPSNGNGNLVEDFEESFQSKLRKLNPAIDILILRDSCEMSGSVDDAGSSGGVAIQVFRPTWDEFKDFNKYVQYMESKGAHKAGLAKVIPPPEWVPRKKGYDLDELNITIPSPICQVVTGKQGLFQQINIQKKSMTVKQFAVLANSAKYCTPRHTNYDDLERKYWKNVTYVAPIYGADVNGSITDPDVKEWNINHLGTILDFVNSDYGIEIDGVNTAYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKTWYVIPPEHGKRFERIAAGFFPTSAKTCQAFLRHKMTLISPQILKQYSLPVNKITQKPGEIMITFPYGYHAGFNHGFNCAESTNFAAPRWVEYGKRALQCTCSNDMVKISMDTFVKRFQPDRYELWLKGQDIGCHPEQPEKMVPAPHPSGQDILCNKNNTELPASFIEAEVEGLKKKKRHPLHLKRAMASKSIRLPQGDLDMMTSMKRPMMPLDPDDTQLDALEDIWLKGDEMDPSEAQLPDIGYIDSDRDSDYKAPQTTKRKQTKTRRKRNSSKSKEKVARSPLKGESSQEQSKKQKRKMKTKKLSDEQLEDMAAVISTWESPPHDNEDVKDKPPSPKVDPLNETVTSQSSALDTTTEELSKTTDKEPKKRKSLPKTDKKDKIKKERVKEPIKREPKVKKEKVEEEKDKKPRKPRIPKIKQEMPLQPDVHNSPKIYTSSTLPRTMAASSASTSKIPLPLNTPPKPYAGLLLDANLRVPTIIQPINKNPSAFEGEFYKFMERKQNSPEHIIPRKSSTDKVIVERVLPESPVKVQDIPLPIGQYNDNIFLDTPIDYRTQPPAGTRANPHPNYPWRPTQRQGSSIQPACLNVLTKQETSPCVEKEEVRVEVERFIDLARLMEAFFLQKRFLLSAMKPELLVKEDNNELKCELQRKEELLRRHSDKISQWQNLLADLQGHTLYNKCQQQPPAPALQQAASPMPQPCSAQQMAAAAQQAALQQQVRPQHPPAYPANVTRR
Length986
PositionHead
OrganismDanaus plexippus plexippus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea> Nymphalidae> Danainae> Danaini> Danaina> Danaus> Danaus.
Aromaticity0.07
Grand average of hydropathy-0.783
Instability index54.64
Isoelectric point9.04
Molecular weight112284.03
Publications
PubMed=22118469

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14159
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     121.79|      19|      19|     630|     648|       1
---------------------------------------------------------------------------
  536-  552 (20.29/ 7.59)	.KGESSQEQSKKQ.K.RK..MK
  577-  589 (22.18/ 9.03)	DNEDV...KDKPP....S..PK
  609-  627 (19.94/ 7.32)	..EELSKTTDKEPKK.RKslPK
  630-  648 (30.37/15.32)	KKDKIKKERVKEPIK.RE..PK
  650-  669 (29.00/14.27)	KKEKVEEEKDKKPRKpRI..PK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.05|      15|      19|     379|     395|       2
---------------------------------------------------------------------------
  379-  395 (26.91/22.47)	GQDIGCHPEQPEkmVPA
  400-  414 (29.15/17.11)	GQDILCNKNNTE..LPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.98|      14|      19|     933|     951|       3
---------------------------------------------------------------------------
  933-  946 (28.32/26.13)	CQQQPPAPALQQAA
  953-  966 (25.66/ 9.09)	CSAQQMAAAAQQAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.90|      13|      53|     721|     742|       4
---------------------------------------------------------------------------
  705-  717 (25.76/17.95)	KIPL...PLNTPPKPY
  727-  742 (19.14/11.35)	RVPTiiqPINKNPSAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.06|      23|      95|      67|     108|       6
---------------------------------------------------------------------------
   67-   92 (34.35/51.65)	KDFNKY.VQYMESkGAHKAGLakVIPP
  234-  257 (42.72/15.90)	EDMDLYsINYLHF.GEPKTWY..VIPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.48|      13|      15|     805|     817|       8
---------------------------------------------------------------------------
  805-  817 (24.35/13.36)	YRTQPPAGTRANP
  823-  835 (25.13/14.05)	WRPTQRQGSSIQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.54|      12|      30|     171|     182|      10
---------------------------------------------------------------------------
  171-  182 (22.44/16.13)	YVAPIYGADVNG
  203-  214 (22.10/15.77)	FVNSDYGIEIDG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14159 with Med28 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KCQQQPPAPALQQAASPMPQPCSAQQMAAAAQQAALQQQVRPQHPPAYPANVTRR
2) KRAMASKSIRLPQGDLDMMTSMKRPMMPLDPDDTQLDALEDIWLKGDEMDPSEAQLPDIGYIDSDRDSDYKAPQTTKRKQTKTRRKRNSSKSKEKVARSPLKGESSQEQSKKQKRKMKTKKLSDEQLEDMAAVISTWESPPHDNEDVKDKPPSPKVDPLNETVTSQSSALDTTTEELSKTTDKEPKKRKSLPKTDKKDKIKKERVKEPIKREPKVKKEKVEEEKDKKPRKPRIPKIKQEMPLQPDVHNSPKIYTSSTLPRTMAASSASTSKIPLPLNTPP
932
435
986
714










Molecular Recognition Features






MoRF SequenceStartStop




1) AYPANVT
2) EAQLPDIG
3) LEDIWLK
4) RIPKIKQ
978
487
473
666
984
494
479
672