<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14145

Description Mediator of RNA polymerase 2 transcription subunit 16
SequenceMELIYSMRRKPLKCEPPHFNSTDPEVVRPICTISIRNIIAFSSLTELSDTDGDTWGGHVYVCDIDTPWDAHKVTSTVHPVSALEWDGEGKQLLVATTVGDVSVFGQKDYLLNEWTCLYTANFPGEHIIQATFFHNGRRVVTVDKKPDVPIYERMQLLRGVWCAGACVVSGSGLVGALTAGEGGRALVATDCMRPARDHLSSASITHKTGSMLIAACFRRGCKRAVRVARCTVSRPSSSKCAPVCIQLQPLPTVYLEDDVTSVSISWWLRDDTDALLIASHNLTLWKMVERSHPLHKLLAKGPVQGSTTPGGGPKTGDCFNTIVWQQAASWQLEGSSPATAVSAARHAAPALAVLVTSRAMHLLTRDSHHYLVSRPIITGGSSEVSSEATPPKKANYGGTVPSGAPCATVHSVAMSWLGAVCVALDTHSQIHVYRLQPQADMSSSQFVSQAVSQLEYGLVAGVDTRDVLLTVGGVSEGVYERLTENFQRQPASFQQYFYHTWLRLRIALCWLSPSSSCSAASLQSLQSALSVWAACVAGLRDDRGDSALLAALANDDLIADDKNLLALEAKADLSSEATSQALQPLQALRRLLQRALNIALTMLASLQPSNLHQLHTHNVYELYSDPVAVSVLRRLVCVSRACGRGGDPLSRPLARLASAHKPDLIEECMSVCLSWTAREWEGPPRCCVSAPHPRQLPLYLEYGVEPDMLRYVPEPPPHAQSDTSASQDMDSIRYMYLGGRGRAARWRQCGRCGARALPEPRAAPHALQRAYDGRYLAHCRCGGNWTLVSNV
Length791
PositionTail
OrganismDanaus plexippus plexippus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea> Nymphalidae> Danainae> Danaini> Danaina> Danaus> Danaus.
Aromaticity0.07
Grand average of hydropathy-0.105
Instability index50.91
Isoelectric point7.91
Molecular weight86125.32
Publications
PubMed=22118469

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14145
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     182.71|      57|      63|     337|     397|       1
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  337-  397 (81.45/72.20)	PATAVSAARHAApALAVLvTSRAMHLLTRDSHHYLVSRPIITGGSSEVSSEATPpkKANYG
  401-  457 (101.26/70.53)	PSGAPCATVHSV.AMSWL.GAVCVALDTHSQIHVYRLQPQADMSSSQFVSQAVS..QLEYG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     369.22|     146|     370|      97|     264|       2
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   62-  169 (115.90/93.89)	...............................................................CDID..TPWDAH..KVTSTVHPVSALEWDGEGKQLLVatTVGDVS..VFGQkdyLlnewtclyTANFPGEHI.IQATFFHNG.R.RVVTVDKKP....DVPIYERMQLLRGVWcaGACVVS
  170-  264 (101.02/74.42)	GSGLVGALTAGEggraLVATD...CMRPARDHLSSASITHKTGSMliaACFRRGCKRAVRVARCTVS..RPSSSKcaPVCIQLQPLPTVYLEDDVTSVSI....................................................................................
  463-  538 (61.87/29.45)	.............................................................................................DTRDVLL..TVGGVSegVYER...L........TENFQRQPAsFQQYFYHTWlRlRIALCWLSPssscSAASLQSLQSALSVW..AACVAG
  545-  631 (90.43/46.69)	DSALLAALANDD....LIADDknlLALEAKADLSSEATSQALQPL...QALRRLLQRALNIALTMLAslQPSNLH......QLHTHNVYELYSDPVAVSV....................................................................................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.02|      34|     106|     640|     676|       3
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  640-  676 (57.93/34.91)	RACGRGG.....DPLSRPLArLASAHKPDLIEECMsvC.LSWT
  747-  786 (61.09/28.58)	RQCGRCGaralpEPRAAPHA.LQRAYDGRYLAHCR..CgGNWT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14145 with Med16 domain of Kingdom Metazoa
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