<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14144
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MANSVNISIEAPIENQIQEITYDGQEIYQAPLSMSENLARLAQKIDFSKTDDEFCNIKKEGDIGSEVKSEEDKEPGYQSSLWPWDSVRNKLRNALTEVSVLADVLSIAKEKRYMVLDPIQADPIESRPMVQVYGRKKALSAAGAVLLNGVERLRASETMRMTRNMPDFHIDLLRLRQNWRLKKVSNTIVGDLSYRTAGSKFSQTGVFEVTKAPEEQIAAAMNAPGAAPSALRVTVPPELQGVAFISVRCQKEQEDVVTATLNSSALNCPGSLPGDGAELHWQQKLEAAQNVLYCKELFARLAAEAVQLDASIPHIVVGNRIMLTILPSIQLMIGLCHNNGQNNNNTEGTKSQGSYVKAEHDHVLEHSLHQLLRAVHHSNTHHPFPHPATGPLGPSKRRSLAGPMGADRYELMEMSREQSLLEQIVQQAQHFFMRRRGEYVLDTIAKEVKDPLIVSHWNALNSPTHSCVKINIMAYGYDAVCRTSLVVHVGEKTLKCICRDGKVRNLSYELQELRDLIFCQIYQHQMTGVQAVGRCMGWQLLASSSHLGAGPVEPLANASSCLLASPNGDRMIAIRCEPSVGIQVFIAQSPKKDFFVSELVQDKKWENLGGAFKEVKLEKMEGKNFLNKMELLMACLSSPS |
Length | 640 |
Position | Head |
Organism | Danaus plexippus plexippus |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea>
Nymphalidae> Danainae> Danaini> Danaina> Danaus> Danaus.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.280 |
Instability index | 46.28 |
Isoelectric point | 6.69 |
Molecular weight | 71060.66 |
Publications | PubMed=22118469
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP14144
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.26| 15| 21| 540| 554| 1
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540- 554 (27.03/15.18) LLAS..SSHLGAGPVEP
562- 578 (23.23/12.17) LLASpnGDRMIAIRCEP
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