<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14136

Description Mediator of RNA polymerase 2 transcription subunit 23 like protein
SequenceMTDSQVANIVNEILRVEAVEEAFSCFLVYKPEQESERLSIYQKKLCSIMSSPSAEVQESAIRQYLTLTAVLTNRYKMKQLLGLLENLVNTNILQARMLCDCILTSEKLVYKNSDYWIECFNLVRRVIGGVDYKGVREIMKGCREKAQTLPVRLNSSTMPQMRALCNVIEYIFDRNASLLPAYFIVTEIQKDYPDNNHWPHWQLAKLLTTFVESFKPCAQMVSIIGHSQMLPVVEFSGYADHLVNPWRLDPTTLKFSLKGNLPYDDELLKPQISLLRHVLQQPYSRDMMCSMLGLQKQHKQRCIALEDQLVELMILPMERSEQENEDDEMPSTHWCWLHLSSQVIYLILIGFASFPSIVMGLHNKLVGCDLKKGRDHLMWVLLQFISGSIQRNPLSNFLPIIKLHELLYPEKEALPMPDYTKAHCTHQMAVVCIWMHLLKKAESEHKTMIMPQNLKVQYEFLQHLMTSNNTPTLMGADYRIALLCNAYSTNQEYYARPMGIIIETLFGNQKPMPNGNPAAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKTTIPGSNMMAPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHNLLDMFSYRIHHIQPHYRVTLLSNINSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSEPKSCVVVSSESEELNRVLVLTLARGIYMTGTGNDGAAVKEILTTIMTNTPHMWSQHTLQCFPPVLVEFFSQNPAPKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGTPLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTNPAGGPHINKCVDAINDIIWKYNIVTIDRLVLCLVLRPNPDGNESQVCLYIIQLLLLKGSELRNRAQDFVKENSPEHWKQNNWYERHSAFHRKYPEKFAPEETSGAYGGPIPVYLSNVCLRFIPVLDIVVHRHLEIPQVSKNLEQLLEHLGYLYKFHDRPVTFLYNTLHYYESKLRDKPLLKRKLVTAVLGSLKEVRAPGWATTEAFQTFLGSETEAWSPDLNYYLSLINRMVDTMMGSSHFPNTDWRFNEYPNPSAHCLYVTCVELMSLPVPPNTVGNNLLDVVTKGFVVIPANKIQLWINAIGIIMAALPDPYWTVVHDRLLELITGTEMVEWTYQHTPFQLFNLTKTNECMLENKYSLTLALAHAVWYHAGPGQIMQVPTFVKEKMSPEIRTEVQLIFLCHLMGPYLQRFNTDLSRAVMDITIVLYELLAHIDKSQTHLQYIDPICDLLYHIKYMFVGDTMKNEVENVIRKLRPALQMRLRFITHLNVEQINTA
Length1335
PositionTail
OrganismDanaus plexippus plexippus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea> Nymphalidae> Danainae> Danaini> Danaina> Danaus> Danaus.
Aromaticity0.09
Grand average of hydropathy-0.065
Instability index43.80
Isoelectric point7.05
Molecular weight153226.79
Publications
PubMed=22118469

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14136
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     239.39|      83|     289|     921|    1023|       1
---------------------------------------------------------------------------
  408-  464 (73.09/36.75)	YPEKEAlpmPDYTKAHCTHQMAV....VCI.WMHLLKKAesEHKTMIMPQNLKVQYEFL.......QHL.............................................
  932- 1023 (132.79/127.85)	YPEKFA...PEETSGAYGGPIPVylsnVCLrFIPVLDIV..VHRHLEIPQVSKNLEQLL.......EHLGYLykfhDRPVTFLYNTLHYY.........ESKLRD.KPLLKRKL
 1265- 1321 (33.51/11.08)	.....................................................VLYELLahidksqTHLQYI....DPICDLLYHIKYMFvgdtmknevENVIRKlRPALQMRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.14|      27|     197|     178|     207|       2
---------------------------------------------------------------------------
  178-  207 (44.09/38.26)	LLPayFIVTEIQKDyPDNNHWPHWQLAKLL
  381-  407 (48.04/29.12)	LLQ..FISGSIQRN.PLSNFLPIIKLHELL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.65|      21|      79|     778|     798|       3
---------------------------------------------------------------------------
  778-  798 (40.77/28.13)	NDIISHFSVPG.TPLFLCLLWK
  854-  875 (33.88/21.95)	NDIIWKYNIVTiDRLVLCLVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     171.76|      53|     192|     484|     576|       4
---------------------------------------------------------------------------
  280-  352 (84.03/39.73)	QQPYSRDM...MCSMLGLQKqhkqrcialedqlvelmilPMERSEQENEDDEMPSThWC.....WLHLSSQVIYLILIGFA
  491-  551 (87.74/100.14)	QEYYARPMgiiIETLFGNQK...................PMPNGNPAAPLPTVPLS.MCildslTLHCKMSLIHSIVTHVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.26|      57|     650|      15|      77|       5
---------------------------------------------------------------------------
   15-   77 (81.48/77.45)	RVeaVEEAFSCFLVYKPEQESERLSIYQKKLCSIMSSPSAEvqESAIRQylTLTAVLTNRYKM
  674-  730 (94.78/68.07)	RV..VSEPKSCVVVSSESEELNRVLVLTLARGIYMTGTGND..GAAVKE..ILTTIMTNTPHM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.15|      20|     210|     876|     895|       9
---------------------------------------------------------------------------
  876-  895 (38.39/20.65)	PNPD......GNESQVCLYI..IQLLLL
 1081- 1108 (28.76/13.74)	PNTDwrfneyPNPSAHCLYVtcVELMSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14136 with Med23 domain of Kingdom Metazoa
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