<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14126

Description Uncharacterized protein
SequenceMGIMYEKRPLKRPRLGPPDVYPQEPRQKEDELTSANVKHGFTTTPQSSDEFGTARNFNYSASKIGQFFSGILSKKEELNTLPDCGRKRQQVNPKDNFWPATARTKPQIEAWFKDLAGNKPLSQLAKKAPNFNKKEEIFITLTEYQVAMPRAAWFIKLSSAYTVAVSEAKIKKRQLPDPTTEWTTTLIKFLKDQIPKLAEHYQSAVPGSVSDKTPPSQSGQGTPSHSCLGNPPGGSTPNSSMVPNSMHSPGLGSSTPNANENTDWRQALRQWNYCCRLARYLLDEGLLDRHDFLTWIIELLDKRAPDDGLLRLFLPLALQHISEFVCCEGLSRRLATSCAKKAAAICSVLSDTTLRALNQPAVFNKTAEKSETTGAPLSPTAEANGDVKPNVSQIKRSVTPADQNQGTPNPNHSLGTPNPNHSLGTPNPLGTPNPQQPMDVQVKEEASSPPRDTKATLTAVIAAALNPVQVGFGEILNCAYHRDVIIQLATILQIICIECPTALVWSGCGSSLQGSPLDLLPLPPSALPMPQMDSTLSQEHRRMAYESEQEIAARSKKAESKWCTDKWQTSSQARVLAVLEALDRHCFDRVDPNNNLDTLYKEVFANCTPTNKEGTLDPKDPEYACSYAVVRVLCEWAVCGARWGEHRAMAAAALLDRRQHHHHHDHQGSDDKESVGSGTGIYNGPPIFQNLLLRFLDNDAPVLDESPNAPPGNRQQFANLVHLFGELIRRDVFSHDAYMCTLISRGDLISPTEPTSTGGTHTVAPPANSTGTNHNIDEDIFAGIDLKPKMEENVRMDLDDSKIDDDLDKLLQHIKEDQQNSMDAPDSPKDPGEPTHGVNSPMMGASGIGIPGMQSIGMGPMSVPGVRGASLSRHYHYTTHFPLPPAEPEHTPHDANQRHILLYGVGRQRDDAKHAVKKVTKGKRNYIFMLCFTEICKLFSKKFSIDVAEGGKIKKHSRSEFNFEAVTQKFQAMSMYEQGAVSWAVGGAVCEALAAYAAGATTYLPQPEHVAFALDLMEIALNVHGLIETCIQILKELSEVEAALITRGAPSSGLAAPRAYTSALALYTVGALRRYHSCLLLCVEQTSAVFEQLCRLVKCVVNPGDCGSAERCVLAQLHDLYKAAAHLFHAPHADTFANAYPKIKQALYSPLTPTPSNYQYNPQFLSEFFTNPRKGKIEIAWARQVAESPANRYSFVCSAMLAVCREVDNDRVNELGVVCAEMTAWCSSLAAEWLGALVALCGAQHYPQHAAPPPLYPDLLHHRDLHDAAAHDALAVFTCILVARHCFSLEDFVRHAALPSLVKACGGGGPLPPNAPSPDAGARLTCHLLLRLFKTVDTPQPGLYSVSTSPGPVGTGAGVRLSCDRHLLAAAHKNIGVGPVLATLKAILMVGDSTARDGMKLSGKKSSELSHILGTSDTVPTDAQLDLMSMVDTEMSGGHRTPRGSGGVGSTLLDSSQSLSSLARRVLAEICSEEWVLQKCLQNPDELYQPDMLLDSMLTPRQAQRLLHMICYPDSASHTHPDLDQKTMITRLLENLEQWSLRMSWLDLQLMFKQFPSGSSELNAWLDTVSRAVINVFQQPAPPPPDKDRMGTERGVVSTSKWSESVWLVAPLVAKLPAAVQGRVLKQAGQILESGWGAGCSGSCSSGGGSGGGSHRDCKSHQSPSYKG
Length1668
PositionKinase
OrganismDanaus plexippus plexippus
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Papilionoidea> Nymphalidae> Danainae> Danaini> Danaina> Danaus> Danaus.
Aromaticity0.06
Grand average of hydropathy-0.333
Instability index46.88
Isoelectric point6.53
Molecular weight181884.61
Publications
PubMed=22118469

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14126
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.10|      11|      15|     399|     410|       1
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  399-  410 (20.43/11.31)	TPaDQNQ..GTPNP
  416-  428 (20.67/ 7.56)	TP.NPNHslGTPNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.07|      34|      38|    1321|    1358|       2
---------------------------------------------------------------------------
 1300- 1341 (51.95/35.98)	SLVKACGGGGPLPPNApspdagaRLTC..HLLLRLFKTVDTpQP
 1342- 1379 (52.11/29.86)	GLYSVSTSPGPVGTGA.....gvRLSCdrHLLAAAHKNIGV.GP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.93|      24|     490|     300|     323|       3
---------------------------------------------------------------------------
  283-  305 (26.09/13.45)	DEGLLdrHDFLTWIIE...............lLDKRAP
  306-  323 (26.90/14.10)	DDGLL..RLFLPLALQHISE..................
  804-  834 (24.94/12.53)	DDDLD..KL.....LQHIKEdqqnsmdapdspKDPGEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     275.13|      85|     489|     495|     587|       4
---------------------------------------------------------------------------
  498-  587 (142.83/86.86)	ECPTALVWSGCGSSLQGSPLDLlplpPSALPMPQMdSTLSQEHRRMAYESEQEIAARSKKAESKWC.TDKWQTSSQAR.VLAVLEALDR...HCF
 1039- 1128 (132.30/63.28)	EVEAALITRGAPSSGLAAPRAY....TSALALYTV.GALRRYHSCLLLCVEQTSAVFEQLCRLVKCvVNPGDCGSAERcVLAQLHDLYKaaaHLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.92|      31|      38|    1463|    1497|       5
---------------------------------------------------------------------------
 1463- 1497 (47.39/42.16)	ARRVLAEICSEEwvlQKCLQNPDeLYQPDM...LLDSM
 1503- 1536 (52.52/32.32)	AQRLLHMICYPD...SASHTHPD.LDQKTMitrLLENL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.36|      11|      16|     228|     238|       6
---------------------------------------------------------------------------
  228-  238 (23.18/11.96)	LGNPP.GGSTPN
  246-  257 (18.18/ 7.40)	MHSPGlGSSTPN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.08|      14|      16|      82|      95|       7
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   82-   95 (25.97/15.88)	PDCGRKRQQVNP..KD
   99-  114 (18.00/ 8.59)	PATARTKPQIEAwfKD
  122-  135 (21.11/11.43)	SQLAKKAPNFNK..KE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.68|      27|      39|     156|     183|       8
---------------------------------------------------------------------------
  156-  183 (40.86/30.00)	KLSSAYTVAVSeAKIKKRQLPDPTTEWT
  196-  222 (46.82/29.96)	KLAEHYQSAVP.GSVSDKTPPSQSGQGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.09|      24|     486|     895|     918|       9
---------------------------------------------------------------------------
  895-  918 (42.09/26.70)	ANQRHILLYGVGRQRDDAKHAVKK
 1382- 1405 (40.00/25.02)	ATLKAILMVGDSTARDGMKLSGKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.87|      17|      43|    1237|    1253|      10
---------------------------------------------------------------------------
 1237- 1253 (34.62/22.94)	LVA.LC.GAQHYPQHAAPP
 1281- 1299 (23.26/12.61)	LVArHCfSLEDFVRHAALP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     269.69|      80|     241|     920|    1000|      11
---------------------------------------------------------------------------
  920- 1000 (132.07/86.50)	TKGKRNYIFMLCFTEICKLFSKKFSIDVAEGGKIKKHSRSEFNF.....EAVTQKFQAMSMYEQGAVSwAVGGAVCEALAAYAAGA
 1152- 1236 (137.62/84.74)	TPTPSNYQYNPQFLSEFFTNPRKGKIEIAWARQVAESPANRYSFvcsamLAVCREVDNDRVNELGVVC.AEMTAWCSSLAAEWLGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.61|      33|      36|    1567|    1602|      13
---------------------------------------------------------------------------
 1567- 1602 (52.39/41.22)	DTVSRAVINVFQQPAPPppdKDRMGTERGVVSTSKW
 1604- 1636 (55.22/33.80)	ESVWLVAPLVAKLPAAV...QGRVLKQAGQILESGW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.89|      13|     117|     760|     772|      16
---------------------------------------------------------------------------
  760-  772 (24.66/11.08)	THTVAPPANSTGT
  879-  891 (27.23/13.03)	THFPLPPAEPEHT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.09|      14|      18|      21|      35|      18
---------------------------------------------------------------------------
   21-   35 (20.92/15.19)	YPQEPrQKEDELTSA
   41-   54 (25.17/13.52)	FTTTP.QSSDEFGTA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14126 with Med12 domain of Kingdom Metazoa
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