<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14117

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMDTKTGRQPSTFAGKVKALLMRAWRERWTDIQWGVQLKKVLASTGGDPKDLPEILVHQALVGPNPNTLILSFLKYTVLSQVVPPSAAFNLITSFDDLSKPFCTLGLIDLAEAFACNLSFTCSLDSSLTLCKCLQNTLHWLMLCIHQSLQMIKDGHTPLEILAIIDSASVAAQKIGDNTTVQALLYVAMSEDTDKFHDFEQTKVNVQGTLSQLQSDVVPSQTRLKVASALKSLLKVQDLALPTQSVLEVSHLAICPTINGLVSLEAILNPTSDVQPFVEQLCVTEKLLKLNRSYLYCELFRACFMGLVDSADSQEELKWAAFTYLKLPQVLLKFNQQAPGQDFGKELEQGFDLLLNSVPLLDLTDVRLNCEALLQLIHECMKYDLLSQPQIERLLTRRRNESAKPAKNSQPTTQPSASLILRAESTVTSILKTLDADCSKNQDALMGVLCQMLSGKSFELILAAAAATGELQSFATKLIKINEFAKQTQGEAGKAAQTRVLLFDISFLMLCHITQLHGIEIFSQMISMSPEYADSFFIQWAQRCLPEDGRYKCVDNYSGTDQAKVDLLLSQLTRGDEIKQSSTKWHEICLNAPFAIQEVLFAWEHGALGSDNVKVILERSQSRMCSIPVVMSAWLCSYMNTVGDDAREKPLQMLQRLQVKISSPDPEIYYGERSHLMGIILRKMVNDILPPHIKDTSMQFIPPNAVPSAVMEKCLKGVMAKGWIDLRSVHTLEQLLNLCGSDWFCDRAILHMLNSSRLEDLTQALGLLFAVFHLDLEHITLSLLLHTVPKLLQSADKQQLLTDPRGYILAKACVLCIVAAQTARSVAGKATMSHTRRGYSKRSRKEMELESLDEPDSRPVKRMKTMEPQLTLDSEGFNLDFLTAKDDGEASPIIDTKDPLNKALANLLRLMNAIAHSTTISPRTSFIVAFIEESIKCGGQYSQFIHQFIPPQMLSQIMKSIPGVFSNQQIVHICNLAVPTGRKVAAKCVCQNSKIRPE
Length997
PositionTail
OrganismMizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Bivalvia> Autobranchia> Pteriomorphia> Pectinida> Pectinoidea> Pectinidae> Mizuhopecten.
Aromaticity0.06
Grand average of hydropathy-0.008
Instability index47.55
Isoelectric point6.45
Molecular weight110917.60
Publications
PubMed=28812685

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14117
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.89|      24|     245|     698|     723|       3
---------------------------------------------------------------------------
  698-  723 (37.78/31.97)	QFIPPNAVpSAVMeKCLKGVMAKGWI
  946-  969 (46.11/28.35)	QFIPPQML.SQIM.KSIPGVFSNQQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     188.51|      59|     259|     246|     341|       4
---------------------------------------------------------------------------
  246-  307 (92.48/109.08)	LEVSHLAIC..PTINGlVSLEAILNPTSD...VQPFVEQLCVTEKLLKLNRSYLYCElfRACFMGLV
  616-  679 (96.03/81.62)	LERSQSRMCsiPVVMS.AWLCSYMNTVGDdarEKPLQMLQRLQVKISSPDPEIYYGE..RSHLMGII
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.10|      39|     358|     193|     233|       5
---------------------------------------------------------------------------
  193-  233 (58.88/43.36)	DKFHDFEQTKVNVqgTLSQLQ..SDVVPSQTR.....LKVASALKSLL
  554-  599 (53.22/32.53)	DNYSGTDQAKVDL..LLSQLTrgDEIKQSSTKwheicLNAPFAIQEVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.38|      14|     260|     500|     513|       6
---------------------------------------------------------------------------
  500-  513 (27.36/17.02)	LLFDISFLMLCHIT
  766-  779 (26.02/15.84)	LLFAVFHLDLEHIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.67|      12|     395|     353|     364|      13
---------------------------------------------------------------------------
  353-  364 (21.07/10.18)	LLNSVPLLDLTD
  751-  762 (21.60/10.60)	MLNSSRLEDLTQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14117 with Med24 domain of Kingdom Metazoa
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