<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14104

Description Peptidase M41
SequenceMDPEGKKFGRGPRELTGAVDLINHYKLWAHHDFFCKRSLPLSISDTHYLHSVVGDTEIKKGEGMELDQLFQSTSYTRDRNAHIQPFDLDTLSKAFQLREAGPIDLPSAEKGIPTIAGKSKSESKDKERKHKKHKDRDKDKDKDKEHKKHKHRHKDRSKEKDKDKKKDKSGHHESGEHSKKHHDKKRKHDGGEDLTDIHKHKKSKKCPPVQVVWSQHREGNLFRAASSSISEIKSINQHIYVRERIQWPVGPVNLNILPNGTAAPTPPYLMVKIRLASSSSFETLVGLKPSIHLKPTRAYRASIIYWNALGFSSRHQLFPALMSADSVLIEKPFHFQAMDTKDFAEEGQERVRSILKEYGVPPFSPLKGLFVQGSFFSSFLMTEMLRAQNGPPGTSMQQAAMDTKDFAEEAQERVKAILKEYGVTPFSPLKGLFVQGSFFSSFLMTAISSYWVSPSFFLHMHGVVKPESPNPEKEGNFRKGVVKPESPGPEKEENFMKHIMKRLLKSSVQTCPGIPNPDDKKTSIEQIKKRFYKYVETVVSDYEKTRKWIELIGQILVVVVGLLAYLYIDHRETQKKPKLVPRGQQKVTGDPQKVQYFFKDVAGCDEAKQDIMELLNFLKDPEKYEEVGAKMPKGVLLIGPPGTGKTLLAKAMANESGLRFIAVSGSEFVELYGGLGAARVRNLFAEAKKSAPCIIFIDEIDAIGLARGDLMHKSTNNERENTLNQLLVELDGFENSSGVFVLASTNRAELLDKALLRPGRFDRVVTVDPPDIRGREEIFEIYLKRIKIENEPAYYSKKLAALTPGFTGADIANVCNEAALIAARYESLNVTMYHFEAALDRIIGGSERKSKVISKLERRTMAYHEAGHVVVGWFLEHAEALRKVSIVPRGTTPVGYSHYNQNENLIKTKEELFDVACMALAGRASEQILLGKISTRANDDLERVTRMAYDQVAKYGFSEKVGLLSFPEDRIMLPYGGKLRDMIDSQAKEWLDKVYHHSLRIIQEHKDEVSQIAELLLEREILYEEDLKKVMGDRPFK
Length1037
PositionHead
OrganismMacleaya cordata
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya.
Aromaticity0.08
Grand average of hydropathy-0.549
Instability index36.87
Isoelectric point9.10
Molecular weight117491.30
Publications
PubMed=28552780

Function

Annotated function 
GO - Cellular Component
membrane	GO:0016020	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATP-dependent peptidase activity	GO:0004176	IEA:InterPro
metalloendopeptidase activity	GO:0004222	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14104
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.36|      15|      15|     130|     144|       1
---------------------------------------------------------------------------
  118-  133 (21.18/ 7.20)	KSKSESKDKERkHKKH
  134-  149 (26.19/10.31)	KDRDKDKDKDKeHKKH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     279.73|      62|      62|     321|     382|       2
---------------------------------------------------------------------------
  321-  364 (71.63/45.60)	...................LMSADSVLIEKPFHFQAMDTKDFAEEGQERVRSILKE....YGVPPFS
  365-  427 (116.71/79.34)	PLKGLFVQGSFFSSFLMTeMLRAQNGPPGTSMQQAAMDTKDFAEEAQERVKAILKE....YGVTPFS
  428-  454 (41.71/23.21)	PLKGLFVQGSFFSSFLMT......................................aissYWVSP..
  455-  486 (49.68/29.17)	.........SFFLH.MHG.VVKPESPNPEK..............EGNFR.KGVVK.........PES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.64|      13|      16|      79|      93|       3
---------------------------------------------------------------------------
   79-   93 (19.38/17.08)	RNAhiQPFDLDTLSK
   98-  110 (22.26/11.93)	REA..GPIDLPSAEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.54|      24|      27|     501|     527|       5
---------------------------------------------------------------------------
  501-  527 (31.84/37.97)	KRLLKSsVQTCpgIPNPDDKKTSIE...QI
  529-  555 (36.70/27.24)	KRFYKY.VETV..VSDYEKTRKWIEligQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.72|      15|      19|     167|     185|       6
---------------------------------------------------------------------------
  150-  165 (22.99/ 6.10)	KHRHKDrSKE...KDKDKK
  168-  185 (24.74/18.53)	KSGHHE.SGEhskKHHDKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     270.21|      87|     161|     598|     690|       8
---------------------------------------------------------------------------
  598-  690 (128.27/108.71)	FKDVAGCDeaKQDI...MELLNFLKDPEKYEEVGAKMPKGVLLIGPPGTGKTLlaKAMANESGLrFIAVSGSEFVELYgGLGAARVRNLFAEAKKS
  761-  850 (141.94/97.57)	FDRVVTVD..PPDIrgrEEIFEIYLKRIKIENEPAYYSKKLAALTPGFTGADI..ANVCNEAAL.IAARYESLNVTMY.HFEAALDRIIGGSERKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.55|      25|      27|     699|     725|       9
---------------------------------------------------------------------------
  699-  725 (37.74/30.20)	EIDAIGLARGDLMHKSTNneRENTLNQ
  729-  753 (40.82/25.97)	ELDGFENSSGVFVLASTN..RAELLDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.18|      26|     305|     558|     587|      10
---------------------------------------------------------------------------
  558-  587 (41.72/38.76)	VVVGllayLYIDHRETQKKPKLVPRGQQKV
  869-  894 (47.47/32.76)	VVVG....WFLEHAEALRKVSIVPRGTTPV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14104 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LREAGPIDLPSAEKGIPTIAGKSKSESKDKERKHKKHKDRDKDKDKDKEHKKHKHRHKDRSKEKDKDKKKDKSGHHESGEHSKKHHDKKRKHDGGEDLTDIHKHKKSKKCPPVQVVWSQHR
97
217










Molecular Recognition Features






MoRF SequenceStartStop




NANANA