<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14100

Description Protein kinase domain
SequenceMANVDGDIEEQEQEQNNPLLVMEEKMYVAVSRDVKESKSTLLWALQNSGGRKICLLHVHQPAQMIPIMGGKFPADKLKPEEVTAFRDLERQKMIRSLNEYLLICSQVGVRAEKVEIEMDSIEKGIIELISRHEIKRLVMGAAADKHYWKKMTMLKSKKAIFVCKQAPVFCHIWFVCKGCLIHTREGSLGGTELQTTPLQVVSPTTGTAQSDRARLRSLSEGQKDHVRLTNPVQDLFRRVKSDNFDSHGGRVTALSTLEGMRAMPMLGSEGSADEWKEIPRRSPSKGSGFSIWSLSEVVEASDSIPLVRYAESEDGLIMPAVHESEEDSQYSSPPNEPVERRITDEMYDQLQQAMAETEDSKREAFEESIRRRKAERYAIDAMRKAKSSERLYTNEVKQRKEMEELLARETLVLKEMKNQQVDIMEELRTAQEQILALERKLNDSDQMVKELEEKIVSAMELLRTLKKERDEMQLERDNAVREAEDFRKRREEEKIISKCPEFFSEFSFLEIEEATSKFDTSLMIGEGGYGCVYRGYLHNTEVAIKMLHSNNLQGHSEFQQEVDVLSRVRHPNIVTLIGACPEAWALIYEYLPGGSLEDRLACKDNTPPLPWQTRTQIAIEICSALIFLHTSNPNSIVHGDLKPANVLLDANFVSKLGDFGICRLIPRDECSSGNTTPFCRTNPKGTLIYMDPEFLGTGELTPKSDVYSFGIVLLRLLTGRPAMVLVKEVQYALEKGNLNAVLDESAGNWPFVQAKQLAQLALRCCELNRRSRPDLESEVWKVLEPLKDSCRASSSFRMGDDEHSQVPPPSYFICPILQQMMREPHVAADGFTYEGEALKEWLDGGNDTSPMTNLKLAHRNLVPNHSLRSAIQEWLQQR
Length878
PositionTail
OrganismMacleaya cordata
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya.
Aromaticity0.06
Grand average of hydropathy-0.483
Instability index52.93
Isoelectric point5.51
Molecular weight99761.78
Publications
PubMed=28552780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14100
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.23|      34|      34|     406|     439|       1
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  406-  439 (54.29/33.44)	LARETLVLKEMKNQQVDIMEELRTAQEQ..ILALER
  441-  476 (49.95/30.23)	LNDSDQMVKELEEKIVSAMELLRTLKKErdEMQLER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.13|      24|      29|     345|     373|       2
---------------------------------------------------------------------------
  345-  373 (31.58/35.32)	EMY..DqlqqAMAETEDSKReAFEESIRRRK
  375-  400 (34.55/22.02)	ERYaiD....AMRKAKSSER.LYTNEVKQRK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     277.87|      91|     124|      52|     151|       3
---------------------------------------------------------------------------
   52-  151 (141.91/109.27)	KICLLHVHQPAqmipiMGG....KFPADKLKPEEVTAFRDLERqkmIRSLNE....YLLICSQVGVRAEKVEIE.MDSiEKGIIELISRHEIKRL..VMGAAADKHYWKKM
  177-  278 (135.95/83.42)	KGCLIHTREGS.....LGGtelqTTPLQVVSPTTGTAQSDRAR...LRSLSEgqkdHVRLTNPVQDLFRRVKSDnFDS.HGGRVTALSTLEGMRAmpMLGSEGSADEWKEI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14100 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GLIMPAVHESEEDSQYSSPPNEPVERRITDEMYDQLQQAMAETEDSKREAFEE
315
367










Molecular Recognition Features






MoRF SequenceStartStop




1) EWKEIPRRS
274
282