<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14091

Description WW domain
SequenceMDSNPQSSGGQPFRPPTVGYMGPAQSFGPPMTMQFQPVPQQHGQPFIPVGSQQFWPAGQGISGSHVGLNTHNQQHPFSQMQQLPPRPGLPGQGPPSSQAPPMPFAQPNRSVASGSPQPPQNTQSLGNHMPVADSMGMPFSSSYTFGPSYGQPLNNSNAPSHYQQISQMHGGQPLLHSASQSAPLQQSSQQPLVTAATVPMTSMQPNTTVQPSSDWQEHTSADGRRYYYNKRTKQSSWEKPLELMTPIERADASTVWKEFTTAEGRKYYYNKVTKQSKWTVPDELKLAREQSEKMAGQSIQSETVMTYESPVVVSVSSIETPSTSSCATMGASSPVPVTPVVSVFNTLSVSESPFILAGPSTISMKAAGINSPVATVTPLPVAVTGNAGLPAALVTTTTTLSSFENSFPRDVAHPANGASVQDLEEAKKGMESAGKINVSLSEEKTVDDEPLVYANKQDAKNAFKSLLESANVESDWSWEQAMRLIINDKRYGALKTLGERKQAFNEYLGQRRKQEAEERRIKQKKAREEFTKMLEECEELTSSTRWSKAIAMFEDDERFNAVERARDREDLFENYLLELQKKERAKAQEEQKRNIMEYRQFLESCDFIKANSQWRKVQDRLDDDERCYRLEKIDRLEIFQEYIRDLEKEEEEQRKIQKEILRRSERKNRDEFRKLMQEHVAAGILTAKTRWHAYCMKVRDLPAYIAVASNTSGSTPKDLYEDVAEGLEKQYHDDKTRIKDAIKLGKITLTSTWTLEDFKAALLEDISFPPISHINLKLVFDELLERIKEKEEKDAKKRQRLADDFSNLLYSIKEITASSNWEECKPLFEDNQEYRSIGEESFSREIFEEYVTHLQEKAKEKERKREEEKAKKEKEREEKEKMKEKERKEKDREHETEKGKERSKKDETESETVDITDPKEERKREKEKDKKHKKRHQSATDDISSEKDDSKKSRRHSSDRRKSRKHAYSPESDSESRHKKHKRDHRDGSRRKSAYEELEDGELGEDGEIR
Length1010
PositionUnknown
OrganismMacleaya cordata
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya.
Aromaticity0.07
Grand average of hydropathy-1.056
Instability index66.22
Isoelectric point6.37
Molecular weight115389.37
Publications
PubMed=28552780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14091
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     227.00|      38|      38|     203|     240|       1
---------------------------------------------------------------------------
  106-  146 (36.24/18.68)	.QP.NRSVasgspQPPQNTQslgNHMPvADSMGMPFS.....SSYTFG
  150-  183 (49.96/28.72)	GQPlNNSN.....AP.SHYQ...QISQ.MHGGQPLLHS.ASQSA...P
  203-  240 (75.66/47.55)	MQP.NTTV.....QPSSDWQ...EHTS.ADGRRYYYNKRTKQSSWEKP
  244-  281 (65.14/39.84)	MTP.IERA.....DASTVWK...EFTT.AEGRKYYYNKVTKQSKWTVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.85|      15|      15|     871|     885|       2
---------------------------------------------------------------------------
  871-  885 (25.54/11.23)	KKEKERE.EKEKMKEK
  887-  902 (20.31/ 7.45)	RKEKDREhETEKGKER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     515.69|      66|      66|     523|     588|       3
---------------------------------------------------------------------------
  424-  455 (37.29/18.29)	.............EEAKKGMES...AGKINVSLSEE....KTV.....DDE...............PLV..Y..............AN
  456-  520 (85.03/51.41)	K.......QDAK.NAFKSLL.E...SANVESDWSWE....QAMRL.IINDKRYGAL...KTLGERKQAFNEYLGQ.RRKQE..AEERR
  523-  588 (105.54/65.64)	Q.......KKAR.EEFTKMLEE...CEELTSSTRWS....KAIAM.FEDDERFNAV...ERARDREDLFENYLLE.LQKKE..RAKAQ
  591-  657 (87.17/52.89)	Q.......KRNI.MEYRQFLES...CDFIKANSQWR....KVQDR.LDDDERCYRL...EKI.DRLEIFQEYIRD.LEKEEeeQRKIQ
  658-  731 (62.27/35.62)	KeilrrseRKNR.DEFRKLMQEhvaAGILTAKTRW.....HAYCMkVRDLPAYIAVasnTSGSTPKDLYEDVAEG.LEKQ.......Y
  733-  796 (59.09/33.41)	D.......DKTRiKDAIK.LGK....ITLTST..WTledfKA.AL.LE.DISFPPI...SHI.NLKLVFDE.LLErIKEKE..EKDAK
  798-  861 (79.30/47.44)	R.......QRLA.DDFSNLLYS...IKEITASSNWE....ECKPL.FEDNQEYRSI..gEESFSRE.IFEEYVTH.LQEKA..KEK..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.94|      23|      24|     946|     968|       4
---------------------------------------------------------------------------
  917-  937 (21.23/ 8.99)	...DPKEERKREKEKdKKH..KKRHQ
  946-  968 (39.11/24.14)	EKDDSKKSRRHSSDR.RKS..RKHAY
  971-  995 (33.61/19.48)	ESDSESRHKKHKRDH.RDGsrRKSAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      89.09|      17|      17|     318|     334|       5
---------------------------------------------------------------------------
  292-  308 (22.85/11.41)	EK.......MA.GQSIQSETVMTYE
  309-  332 (23.65/12.05)	SPvvvsvssIE.TPSTSSCATMGAS
  333-  350 (20.58/ 9.58)	SP.......VPvTPVVSVFNTLSVS
  352-  370 (22.01/10.74)	SP.....fiLA.GPSTISMKAAGIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     146.99|      31|      32|       5|      36|       6
---------------------------------------------------------------------------
    5-   36 (61.77/36.50)	PQSSGGQ.PFRPPTVGyMGPAQSF........GPPMTMQFQ
   39-   71 (41.55/19.33)	PQQH.GQ.PFIP..VG....SQQFwpagqgisGSHVGLNTH
   76-  102 (43.66/20.66)	PFSQMQQlPPRPGLPG.QGPPSSQ........APPM.....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14091 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KAKEKERKREEEKAKKEKEREEKEKMKEKERKEKDREHETEKGKERSKKDETESETVDITDPKEERKREKEKDKKHKKRHQSATDDISSEKDDSKKSRRHSSDRRKSRKHAYSPESDSESRHKKHKRDHRDGSRRKSAYEELEDGELGEDGEIR
2) MDSNPQSSGGQPFRPPTVGYMGPAQSFGPPMTMQFQPVPQQHGQPFIPVGSQQFWPAGQGISGSHVGLNTHNQQHPFSQMQQLPPRPGLPGQGPPSSQAPPMPFAQPNRSVASGSPQPPQNTQSLGNHMPVADSMGMPFSSSYTFGPSYGQPLNNSNAPSHYQQISQMHGGQPLLHSASQSAPLQQSSQQPLVTAATVPMTSMQPNTTVQPSSDWQEHTSADGRRYYYN
857
1
1010
229










Molecular Recognition Features






MoRF SequenceStartStop




1) KHKKR
2) RHKKHKRDHR
3) RRKSAYEELEDGELGED
931
977
990
935
986
1006