<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14089

Description Protein kinase domain
SequenceMAPPHISSSEDDRVNSYSCTAVAIDKDKNSQFAVKWAIDNLFNNNPNLVLIHVRTTPKLQHRRLVGLKRSGPPFSCKMRLGSWAASNFKMCSNLLSNFGDFKGTLQNVIGRPVQAKEVILEDSDVSKALLDYISTNCINNIVVGASTRNALTRKFRNTADVPTSIAKSAPEFCAVYVISKGKVLTSRAASRPASNTAAPPRQSSLAGLPPSLQPDPSVDPEDSSVRAPFSRRSLRTGAVTPPERRSLDRGNEYMKSPARERPLSSAKNTPNDALMMDNFDLSMRPQRATHSRDSFSDDIDFTGGLTFRSCDISNENLEFSNNTDETPRNSVSSQPSRELEAEMRRLKLELRQTMDMYSTACKEAISAKQKAQELHQWKVEEARKFEEARLAEEAALQIAEMEKAKCKAAIEAAEAAQRLAEMESQRRRNAEMKAMKEAAEKKRALDALAHNDVRYRKYTLEEIEAATNNFADSLKIGEGGYGPVYKATLDHTRVAIKVLRPDAAQGKKQFQQEIEVLSCMRHPNMVLLLGACPEYGCLVYEYMDYGSLDDRIFRRGNTPPIPWRVRFKIAAEIATALLFLHQAKPEPLVHRDLKPANILLDHNYVSKISDVGLSRLVPPSVADTVTQYRMTSTAGTFCYIDPEYQSTGMLGVKSDIYSFGILLLQIVTAKPPMGLTHHVERAIERGTFAEMLDPMIPDWPMEDVLSYAKMALKCAELRRKDRPDLGSVVLPELNRLRNLGGSESSVMSHSFPPRSPDVSRQKLSNASQNQEGMKSNATSGTSRRSSIEELSRNSSPVMSSGGGRPPKIMFEDDEDK
Length816
PositionTail
OrganismMacleaya cordata
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya.
Aromaticity0.06
Grand average of hydropathy-0.524
Instability index55.11
Isoelectric point8.80
Molecular weight90789.17
Publications
PubMed=28552780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14089
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.50|      26|      27|     216|     241|       1
---------------------------------------------------------------------------
  192-  209 (25.35/ 9.43)	.......PA.SNTAAPPRQSSL...AGLP
  216-  241 (45.73/22.52)	P...SVDPEDSSVRAPFSRRSLRTGAVTP
  242-  270 (39.43/18.48)	PerrSLDRGNEYMKSPARERPLSSAKNTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.34|      56|     475|     114|     172|       2
---------------------------------------------------------------------------
  114-  172 (80.72/85.96)	QAKEVILEDSDVSKA..LLDY.....ISTNCINNIvVGASTRNALTrKFRNTADVPTsIAKSAPEF
  582-  644 (89.62/76.97)	QAKPEPLVHRDLKPAniLLDHnyvskISDVGLSRL.VPPSVADTVT.QYRMTSTAGT.FCYIDPEY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.65|      18|     475|     320|     337|       3
---------------------------------------------------------------------------
  296-  313 (29.80/21.64)	SDDIDFTGGLTFRSCDIS
  320-  337 (29.84/21.68)	SNNTDETPRNSVSSQPSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     119.22|      25|      25|     404|     428|       5
---------------------------------------------------------------------------
  341-  374 (24.92/12.83)	AEMRRLKlelRQtmdmysTACKEAISAKQKAQEL
  375-  398 (31.58/18.11)	HQWKVEE...AR.......KFEEARLAEEAALQI
  399-  419 (30.24/17.05)	AEME.............kAKCKAAIEAAEAAQRL
  420-  445 (32.48/18.82)	AEMESQR...RR.....nAEMKAMKEAAEKKRAL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14089 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSESSVMSHSFPPRSPDVSRQKLSNASQNQEGMKSNATSGTSRRSSIEELSRNSSPVMSSGGGRPPKIMFEDDEDK
2) ISNENLEFSNNTDETPRNSVSSQPSRELEAEMRR
3) RAASRPASNTAAPPRQSSLAGLPPSLQPDPSVDPEDSSVRAPFSRRSLRTGAVTPPERRSLDRGNEYMKSPARERPLSSAKNTPNDALMMDNFDLSMRPQRATHSRDSFSDD
741
312
187
816
345
298










Molecular Recognition Features






MoRF SequenceStartStop




1) GGRPPKIMFEDDEDK
802
816