<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14076

Description Protein kinase domain
SequenceMEILENVEEFAVQPPTSLTVVVAVNISRRSRYAIKWALEKFVAEGRKVFKMLHVRPCITSIPTPMGNYVPISQVRDDVATAYKNEVEWRTTRMLRPFKEMFSENKVEVEVVVIEADDVALAISGEVAKHQISELVIGASSTSMFTRKLKGQNISSRISECTPSFCTIYVVSKGKLSSVRPSTSETSGAIIDENSDTKSTSEKSRAIKDNYSDTKSTSERSEAIKDDTSDTSSSIDSCSSYNFSSQADQEGSFDSYSHVKYPSLDIQRFEALSTINQTLLNKRPSTNHSRHPSLNIEDRKDSRSSYTCNSDSSQSGVSNYRSFQTHYPSWYSDKASTSDVPPNSSSSECQVDVNFDLERLRVEIRHVRGMFAVAQNETINASRQLKNLTERRMEESAKLKEISLREERARELSREEKEKQEAAKRELELVMECVKKEASRRKEAESKSARDAKEKQKLEKALEDPGQQYMKFKWEEIFLATSSFSDDLRIGMGAYGTVYKCNLQNTAAAVKVLHSKEGHGNKEFQQELEILSKIRHPHLLLLLGACPDQGCLVYEYMENGNLEDRLFRKNNTPPIPWFDRYRIAWEVASALLFLHNSKPKPIIHRDLKPANILLDHNFVSKIGDVGLSTWLPTINSSVSTMYTDSDLVGTLCYIDPEYQRSGSISPKSDVYAFGMVILQLLTAKPALALAYNVETALENGNLMEILDSEAGNWPIEETQELAVMGISCAELSASDRPDLEAKVLPFLEKLKGIADKLRNFAPSVQSAPPNHFICPILKDVMENPCVAADGYTYDRKEIENWLKENEKSPMTNMPLPNKNLIPNYSLLAAIMEWKSKTQ
Length837
PositionTail
OrganismMacleaya cordata
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya.
Aromaticity0.07
Grand average of hydropathy-0.517
Instability index47.09
Isoelectric point5.85
Molecular weight94348.55
Publications
PubMed=28552780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14076
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.00|      13|      15|     182|     194|       1
---------------------------------------------------------------------------
  192-  208 (18.13/ 7.28)	ENSdtksTSEKSRAIKD
  209-  225 (18.88/ 7.84)	NYSdtksTSERSEAIKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     174.31|      33|      33|     287|     319|       2
---------------------------------------------------------------------------
  235-  252 (21.58/ 9.51)	.............DSCSSYNFSSQADQEG...SF
  257-  282 (40.81/25.44)	HVKYPSLDIQ.RFEALS..TIN....QTLLN.KR
  287-  319 (60.96/42.14)	HSRHPSLNIEDRKDSRSSYTCNSDSSQSGVS.NY
  323-  354 (50.96/33.85)	QTHYPSWY.SD.KASTSDVPPNSSSSECQVDvNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.67|      25|      33|     399|     423|       3
---------------------------------------------------------------------------
  399-  423 (39.86/30.55)	KEISLREERARELSREEKEKQEAAK
  435-  459 (39.81/30.50)	KEASRRKEAESKSARDAKEKQKLEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.24|      11|      39|      76|      86|       4
---------------------------------------------------------------------------
   76-   86 (20.10/15.96)	DDVATAYKNEV
  116-  126 (19.14/14.81)	DDVALAISGEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.54|      36|     137|     538|     574|       5
---------------------------------------------------------------------------
  538-  574 (62.41/48.34)	LLLLLGACPDQGcLVYEY...MENGNLEDRLFRKNNTPPI
  676-  714 (58.13/38.91)	ILQLLTAKPALA.LAYNVetaLENGNLMEILDSEAGNWPI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14076 with Med32 domain of Kingdom Viridiplantae
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