Description | Protein kinase domain |
Sequence | MEILENVEEFAVQPPTSLTVVVAVNISRRSRYAIKWALEKFVAEGRKVFKMLHVRPCITSIPTPMGNYVPISQVRDDVATAYKNEVEWRTTRMLRPFKEMFSENKVEVEVVVIEADDVALAISGEVAKHQISELVIGASSTSMFTRKLKGQNISSRISECTPSFCTIYVVSKGKLSSVRPSTSETSGAIIDENSDTKSTSEKSRAIKDNYSDTKSTSERSEAIKDDTSDTSSSIDSCSSYNFSSQADQEGSFDSYSHVKYPSLDIQRFEALSTINQTLLNKRPSTNHSRHPSLNIEDRKDSRSSYTCNSDSSQSGVSNYRSFQTHYPSWYSDKASTSDVPPNSSSSECQVDVNFDLERLRVEIRHVRGMFAVAQNETINASRQLKNLTERRMEESAKLKEISLREERARELSREEKEKQEAAKRELELVMECVKKEASRRKEAESKSARDAKEKQKLEKALEDPGQQYMKFKWEEIFLATSSFSDDLRIGMGAYGTVYKCNLQNTAAAVKVLHSKEGHGNKEFQQELEILSKIRHPHLLLLLGACPDQGCLVYEYMENGNLEDRLFRKNNTPPIPWFDRYRIAWEVASALLFLHNSKPKPIIHRDLKPANILLDHNFVSKIGDVGLSTWLPTINSSVSTMYTDSDLVGTLCYIDPEYQRSGSISPKSDVYAFGMVILQLLTAKPALALAYNVETALENGNLMEILDSEAGNWPIEETQELAVMGISCAELSASDRPDLEAKVLPFLEKLKGIADKLRNFAPSVQSAPPNHFICPILKDVMENPCVAADGYTYDRKEIENWLKENEKSPMTNMPLPNKNLIPNYSLLAAIMEWKSKTQ |
Length | 837 |
Position | Tail |
Organism | Macleaya cordata |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.517 |
Instability index | 47.09 |
Isoelectric point | 5.85 |
Molecular weight | 94348.55 |
Publications | PubMed=28552780 |
Annotated function |
Functions as an E3 ubiquitin ligase.
ECO:0000256 ARBA:ARBA00003861 |
GO - Cellular Component | |
GO - Biological Function | ATP binding GO:0005524 IEA:UniProtKB-UniRule protein serine/threonine kinase activity GO:0004674 IEA:UniProtKB-KW ubiquitin-protein transferase activity GO:0004842 IEA:InterPro |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP14076 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 37.00| 13| 15| 182| 194| 1 --------------------------------------------------------------------------- 192- 208 (18.13/ 7.28) ENSdtksTSEKSRAIKD 209- 225 (18.88/ 7.84) NYSdtksTSERSEAIKD --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 4| 174.31| 33| 33| 287| 319| 2 --------------------------------------------------------------------------- 235- 252 (21.58/ 9.51) .............DSCSSYNFSSQADQEG...SF 257- 282 (40.81/25.44) HVKYPSLDIQ.RFEALS..TIN....QTLLN.KR 287- 319 (60.96/42.14) HSRHPSLNIEDRKDSRSSYTCNSDSSQSGVS.NY 323- 354 (50.96/33.85) QTHYPSWY.SD.KASTSDVPPNSSSSECQVDvNF --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 79.67| 25| 33| 399| 423| 3 --------------------------------------------------------------------------- 399- 423 (39.86/30.55) KEISLREERARELSREEKEKQEAAK 435- 459 (39.81/30.50) KEASRRKEAESKSARDAKEKQKLEK --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 39.24| 11| 39| 76| 86| 4 --------------------------------------------------------------------------- 76- 86 (20.10/15.96) DDVATAYKNEV 116- 126 (19.14/14.81) DDVALAISGEV --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 120.54| 36| 137| 538| 574| 5 --------------------------------------------------------------------------- 538- 574 (62.41/48.34) LLLLLGACPDQGcLVYEY...MENGNLEDRLFRKNNTPPI 676- 714 (58.13/38.91) ILQLLTAKPALA.LAYNVetaLENGNLMEILDSEAGNWPI --------------------------------------------------------------------------- |
IDR Sequence | Start | Stop |
1) INQTLLNKRPSTNHSRHPSLNIEDRKDSRSSYTCNSD 2) STSETSGAIIDENSDTKSTSEKSRAIKDNYSDTKSTSERSEAIKDDTS | 274 181 | 310 228 |
MoRF Sequence | Start | Stop |
NA | NA | NA |
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