<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14075

Description Protein kinase domain
SequenceMASICSDDRSIASSTSTVVAVAVRGSSRSSRRAFRWAVDNLMTHGDRFVLIHVIPPITSIPTPSGSRIPIKQMDANVVATYRKDMKSKCEEIFLPFKALCKTKEMESLVLEDENPSYALLRYISESGCNNLVLGSSSSNFITRKLKGRDIASTLLKFVTNTCNIYVVSRNKLIKKLANPSSSAETSAGNSMHTLTEYRESSSTSGEHIYTLHSRTTSEASSEVSDLFGRGYTNRDSFASSVVEDNQGGNHVFMTSFKDAKQSKFQAELEGLQLELRTTLDMYDRACEDLVHIQKKVQALSSECIEEARRVRAVMEREEMWRKTAAEEKCKHLEAMKELEVAKELLAKEVHERQRAELSALTKSSERQKLIDALFSEDKRYRRYTRDEIEVATDFFCETKKIGEGAYGKVYKCSLDHTPVAVKVLQPDESDKTKKEEFLREVEVLSQLRHPHLVLLLGACPEIGCLVYEYMENGSLEERLFCKEGTEPLPWFIRFQIAFDVACGLTFLHGSEPEPIIHRDLKPGNILLDRNYVSKIGDVGLAKFMSSVVPDNVTEYRNSTLAGTLSYMDPEYYRTGTLRPKSDVYAFGIIILQLLTARHPNGLVVSVENAINNGSFGDILDKSISDCPIVEAEELAWIALHCSKLRCRDRPDLKSEVLPVLEKLSSLASVQLQKGNIYTPSYYFCPILQEVMDDPHIAADGFTYEYAAIKAWLEKQKVSPVTRLMLPHTVLTPNHTLRSAIQEWKQHVPRS
Length750
PositionTail
OrganismMacleaya cordata
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya.
Aromaticity0.07
Grand average of hydropathy-0.328
Instability index47.41
Isoelectric point6.41
Molecular weight84541.56
Publications
PubMed=28552780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14075
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.70|      16|      17|     178|     194|       1
---------------------------------------------------------------------------
  178-  194 (24.23/17.62)	NPSSSAETSaGNSMHTL
  196-  211 (28.47/16.28)	EYRESSSTS.GEHIYTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.80|      12|      17|     217|     231|       2
---------------------------------------------------------------------------
  217-  228 (21.10/21.49)	SEASSEVSDLFG
  236-  247 (21.71/ 9.52)	SFASSVVEDNQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.77|      21|     294|     329|     396|       4
---------------------------------------------------------------------------
  293-  327 (26.13/62.01)	QKKVQALSSEcieearrvravmerEEMWRKTAAEE
  367-  387 (36.64/20.72)	QKLIDALFSE..............DKRYRRYTRDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.44|      19|     369|     134|     155|       7
---------------------------------------------------------------------------
  134-  155 (27.70/26.00)	GSSSSNFITRKLKGRDIastLL
  509-  527 (35.74/24.23)	GSEPEPIIHRDLKPGNI...LL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.14|      20|     615|      60|      79|       8
---------------------------------------------------------------------------
   60-   79 (37.64/22.66)	IPTPSGSRIPIKQ..MDANVVA
  676-  697 (37.50/22.55)	IYTPSYYFCPILQevMDDPHIA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14075 with Med32 domain of Kingdom Viridiplantae
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