<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14070

Description WW domain
SequenceMTSNSQSSGTQPLWPPIVGSAGPPQNFGPPMNMQFRPVGQQQQAQPFIPGASQQFRPVGQGIPVPNVGLSSAQSQQLQFPQSMHQLPPRSGQPGHGPPSSQAIQMPFMPQNRPITSGSPQPQQNTQPLSNHMPGVGGSGMPPSYTFAPSYGQPQNNINAPSHYQPISQMHTPVVPAGGQPWLSSGAGSQSTPLVAPLQQTGQQPTVTAATVPATNVQPNPAIQSSSDWQEHTSADGRRYYYNKKTRQSSWEKPLELMTPIERADASTDWKEFNTSDGRKYYYNKVTKQSKWTIPEELKLARDQAEKVASQGIQSESAVTSQTPASLNVPSLETPSIPSSATSGTTSSPVPVTPSVAVVNPPPIMASGSPSIPVLSSALSTDAVGVQSPVATVTALPNPVSGNAGVPAASTTPTTTTSTLENIAPKDVANSLDGASVQDLEEARKGMAVAGKINVTPSEEKAVDEETLIYANKQEAKNAFKALLESANVESDWNWDQAMRVIINDKRYGALKTLGERKQAFNEYLGQRKKQEAEERRIKQKKAREEFAKMLEESKELTSSTRWSKAVTMFEDDERFKAVERARDREDLFENYLVELQKKEKAKAQEEHKRNIMEYRQFLESCDFIKPNSQWRKVQDRLEDDERCSRLEKIDRLEIFQEYIRELEKEEEEQRKIQKEQLRRAERKNRDEFRKLMEGHVAAGILTAKIHWRDYCMKVKDLPAYIAVSSNTSGSTPKDLFEDVAEELEKQFREDKTRIKDAMKLGKITIASTWTFEDFKAAISEDVNSSPVSDINLQLVFDELLERIKEKEEKEAKKRQRLADDFSDLLRSIKDITASSKWEDCKSLFEDSQEYRSIVEESFKREIFEEYITHLQEKAKEKERKREEEKAKKEKEREEKERRKEKERKEKERDRERDKEKERSKKDETESESVDVTDMKEERKREKDKDRKHRKRHQSAADDLSSEKEEKEDSKKSRRHSSSRKKSRKHAYTPESDSEGGHKRHRRDHRDGSRRNGTHEELEDGELGEDGEIRGSVTRNLRIAVKEFVVWTWCHSSVSRMPTHEQQRLDNSVRMELLQRILVGKHYLLDPKFYCNHIFTTIFSTQAAWKSSPGLGSICRKGQEGVQLRRCRHSLGIAHDVGFGELIQYCHLVVPSTHLKST
Length1157
PositionUnknown
OrganismMacleaya cordata
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Ranunculales> Papaveraceae> Papaveroideae> Macleaya.
Aromaticity0.06
Grand average of hydropathy-0.990
Instability index63.03
Isoelectric point8.21
Molecular weight131250.18
Publications
PubMed=28552780

Function

Annotated function 
ECO:0000256	PIRNR:PIRNR023869
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP14070
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     210.79|      38|      38|     218|     255|       1
---------------------------------------------------------------------------
  119-  146 (36.97/15.40)	.............................PQ.PQ.QNTQPLSN....HM...PGVGGSGMPPSYTF
  147-  188 (40.76/17.73)	APS.........YGQP...............qNNINAPSHYQPisqmHTpvvPAGGQPWLSSGAGS
  189-  246 (53.68/25.65)	QSTplvaplqqtGQQPTVtaatvpatnvqPN.PAIQSSSDWQE....HT...SADGRRYYYNKKTR
  247-  287 (56.87/27.61)	QSS.........WEKPLE........lmtPI.ERADASTDWKE....FN...TSDGRKYYYNKVTK
  288-  324 (22.51/ 6.54)	QSK.........WTIPEElklardqaekvAS.QGIQSESAVTS....QT...PA............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      94.45|      17|      17|     876|     892|       2
---------------------------------------------------------------------------
  532-  548 (20.94/ 8.08)	AEERRIKQKKARE.EFAK
  876-  892 (28.18/13.58)	EKERKREEEKAKK.EKER
  894-  908 (26.27/12.13)	EKERRKEKE..RK.EKER
  909-  926 (19.06/ 6.65)	DRERDKEKERSKKdETES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.08|      16|      17|      25|      40|       3
---------------------------------------------------------------------------
   18-   37 (27.75/14.78)	VGS....agppQNFGPPMNMQFRP
   38-   57 (25.94/13.30)	VGQ....qqqaQPFIPGASQQFRP
   90-  113 (23.39/11.22)	SGQpghgppssQAIQMPFMPQNRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.37|      22|      23|     933|     954|       4
---------------------------------------------------------------------------
  933-  954 (40.37/21.22)	DMKEERKR....EKDKD...RKHRKRHQS
  958-  977 (32.09/15.34)	DLSSE.KE....EKE.D...SKKSRRHSS
  978- 1005 (19.92/ 6.70)	SRKKSRKHaytpESDSEgghKRHRRDHR.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     357.36|      51|      65|     549|     599|       5
---------------------------------------------------------------------------
  481-  531 (66.80/41.91)	ALLE......................SA..........NVESDWNWDQAMRVIINDKRYGA.L...KTLGER..KQA.....FNEYLGQRKKQE
  549-  599 (80.89/52.42)	MLEE......................SK..........ELTSSTRWSKAVTMFEDDERFKA.V...ERARDR..EDL.....FENYLVELQKKE
  617-  666 (74.08/47.34)	FLES......................CD..........FIKPNSQWRKVQDRLEDDERCSR.L...EKI.DR..LEI.....FQEYIRELEKEE
  672-  746 (43.54/24.56)	IQKEqlrraerknrdefrklmeghvaAG..........ILTAKIHWRDYCMKVKDLPAYIA.VssnTSGSTP..KDL.....FEDVAEELEKQ.
  748-  807 (28.74/13.52)	..RE......................DKtrikdamklgKITIASTWT.....FED...FKA.A.isEDVNSSpvSDInlqlvFDELLERIKEKE
  824-  873 (63.32/39.32)	LLRS......................IK..........DITASSKWEDCKSLFEDSQEYRSiV...EESFKR..E.I.....FEEYITHLQEK.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     126.02|      32|      33|     327|     358|       6
---------------------------------------------------------------------------
  327-  358 (57.55/35.38)	N..VPSLE...TPSIP..SSATSGTTS.SPVPVTPSVAVV
  359-  392 (41.40/23.17)	N..PPPIMasgSPSIPvlSSA..LSTD.A.VGVQSPVATV
  402-  430 (27.07/12.34)	NagVPAAS...T..TP..TTTTSTLENiAPKDVANS....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14070 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KAKEKERKREEEKAKKEKEREEKERRKEKERKEKERDRERDKEKERSKKDETESESVDVTDMKEERKREKDKDRKHRKRHQSAADDLSSEKEEKEDSKKSRRHSSSRKKSRKHAYTPESDSEGGHKRHRRDHRDGSRRNGTHEELEDGELGEDGEIRGS
2) MTSNSQSSGTQPLWPPIVGSAGPPQNFGPPMNMQFRPVGQQQQAQPFIPGASQQFRPVGQGIPVPNVGLSSAQSQQLQFPQSMHQLPPRSGQPGHGPPSSQAIQMPFMPQNRPITSGSPQPQQNTQPLSNHMPGVGGSGMPPSYTFAPSYGQPQNNINAPSHYQPISQMHTPVVPAGGQPWLSSGAGSQSTPLVAPLQQTGQQPTVTAATVPATNVQPNPAIQSSSDWQEHTSADGRRYYYNKKT
3) TIPEELKLARDQAEKVASQGIQSESAVTSQTPASLNVPSLETPSIPSSATSGTTSSPVPVTPSVAVVNPPPIMASGSPSI
4) VQSPVATVTALPNPVSGNAGVPAASTTPTTTTSTLENIAPKDVANSLDGASVQDLE
873
1
292
385
1031
245
371
440










Molecular Recognition Features






MoRF SequenceStartStop




NANANA