<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14051

Description Uncharacterized protein
SequenceMVHVSFDSNLTGNRTSKNFFGRGNLNLIMTSPALDKHPYTLANLPYGVISTPSSPKPRCAVAIGNHAIDLAAYAKPGRFFDLESGHNFMLAQIFSEPALNSFAALPWPTRRAVRQQLQEELKAGKVPAECLVDLSEVKNHVPMKMGGFSDFYTSLEHCQNCSGEMTSAAIAKNWWYAPSVYNSRVSSVLPSPHDIPRPKNVYFSNGVDSEPTYGPTQKMDFELEMGYFVSKPVPFGEPMPIADAKEHIFGFVMLNDWSARDHQLFEMRPLGPFHSKGFGTSISNWVVPMEALEEFSCPPNTKQDPAPFPHLTWPGQGDGALDIKLRIRLNRNGQEKELGTSNLKYLYWTPYQQLTHHAASGCGMETGDLIGTGTISGSGRNEKGEKCELGCLYEGERTKTQVMPQSTGSKYQEGYIEDGDEIILEGWPSIQRDAELTVMNLARAQDAMNEFGAFFRAAHAYPLPSYPGHEKEMMLGMLMRKKLDPKTDDWVTQYSKSPETGDASKTNMDDLRDLWDYAGPAENGIVREMLENDAFGSLFTMAEQEDGIENVKTGLRRKLFEDDSDEDEDEDAEENGDEKMDEDRQPDKLAPPPEPGVDPSLPPMRLETVLRFITTGAMPPQR
Length622
PositionHead
OrganismHortaea werneckii EXF-2000
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Teratosphaeriaceae> Hortaea.
Aromaticity0.09
Grand average of hydropathy-0.586
Instability index40.26
Isoelectric point4.93
Molecular weight69409.24
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
fumarylacetoacetase activity	GO:0004334	IEA:UniProtKB-EC
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
L-phenylalanine catabolic process	GO:0006559	IEA:UniProtKB-UniPathway
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
tyrosine catabolic process	GO:0006572	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14051
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     597.27|     189|     205|     148|     344|       1
---------------------------------------------------------------------------
  148-  344 (308.11/181.04)	FSDFYTSLEHcQNCSG.EMTSAAIAKNWWYAPSVYNSRVSSV.LPSPHDIPRPKNVYFSNGVDSEPTYGPTQKMDFELEMGY.FVSKPVPFgEPMPIADAKEHI..FG..FVMLNDW...SARDHQLfEMRpLGPFHSKGFGTSISNWVVPMEALEEFSCPPNTKQDpaPFPHLtWPGQGDGALDIkLRIRLNRN..GQ.....EKELGTSNLK
  347-  552 (289.15/145.24)	YWTPYQQLTH.HAASGcGMETGDLIGTGTISGSGRNEKGEKCeLGCLYEGERTKTQVMPQSTGSKYQEGYIEDGDEIILEGWpSIQRDAEL.TVMNLARAQDAMneFGafFRAAHAYplpSYPGHEK.EMM.LGMLMRKKLDPKTDDWVTQYSKSPETGDASKTNMD..DLRDL.WDYAGPAENGI.VREMLENDafGSlftmaEQEDGIENVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.84|      16|      18|     561|     576|       3
---------------------------------------------------------------------------
  561-  576 (26.72/13.25)	EDDSDEDEDEDAEENG
  581-  596 (30.12/15.86)	DEDRQPDKLAPPPEPG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14051 with Med8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NVKTGLRRKLFEDDSDEDEDEDAEENGDEKMDEDRQPDKLAPPPEPGVDPSLPPMRLETVLRFITTGAMPPQR
550
622










Molecular Recognition Features






MoRF SequenceStartStop




1) LRRKL
2) MDEDRQPDK
3) SLPPMRLETVLRFITTGAMPP
555
580
600
559
588
620