<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP14047

Description Uncharacterized protein
SequenceMTSPALDQQPYTLANLPYGVVSTPSNPKPRCAVAIGSHAIDLAAYAKPGRFFDLESGHNFMLAQIFSEPALNSFAALPWPTRRAVRQQLQEELKAGKVPAECLVNLSEVKNHVPMKMGGFSDFYTSLEHCQNCSGEMTSAAIAKNWWYAPSVYNSRVSSVLPSPHDIPRPKNVYFSNGVDSEPTYGPTQKMDFELEMGYFVSKPVPYGEAMPIADAKEHVFGFVMLNDWSARDHQLFEMRPLGPFHSKGFGTSISNWVVPMEALEEFSCPPNTKQDPAPFPHLTWPGQGDAALDIKLQIRLNRNGQEKELGTSNLKYLYWTPYQQLTHHAASGCGMETGDLIGTGTISGSGRNDKGEKCELGCLYEGERTKTQVMPQSTGSKYQEGYIEDGDEIILEGWCENKQGEVVLGPSIQRDAELAVMNLARAQDAMNEFGAFFRAAHAYPLPSYPGHEKEMMLGMLMRKKLDPKTDDWVTQYSKSPETIQENGDVSKLNMDDLRDLWDYAGPAENGIVREMLENDAFGSLFTMAEQEDGIENVKTGLRRKLFEDDSDEEEEDAEEKGNEKMDEDRLPEKLAPPPEPGVDPSLPPMRLETVLRFITTGAMPPQR
Length608
PositionHead
OrganismHortaea werneckii EXF-2000
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Dothideomycetidae> Mycosphaerellales> Teratosphaeriaceae> Hortaea.
Aromaticity0.09
Grand average of hydropathy-0.568
Instability index42.35
Isoelectric point4.84
Molecular weight67774.53
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
fumarylacetoacetase activity	GO:0004334	IEA:UniProtKB-EC
metal ion binding	GO:0046872	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
L-phenylalanine catabolic process	GO:0006559	IEA:UniProtKB-UniPathway
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
tyrosine catabolic process	GO:0006572	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP14047
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.86|      32|     215|     238|     276|       5
---------------------------------------------------------------------------
  238-  276 (50.94/48.73)	EMRpLGPFHSKGFGTSISNWVvpmealEEFSCPPNTKQD
  455-  486 (58.92/36.46)	EMM.LGMLMRKKLDPKTDDWV......TQYSKSPETIQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     179.71|      56|     138|       1|      58|       6
---------------------------------------------------------------------------
    1-   58 (96.40/59.87)	MTSPALDQQ....PYTLANLPYGVVSTPSN.PKPRCAVAigSHAID.LAAYAKPGRF.FDLESGH
  137-  199 (83.30/46.08)	MTSAAIAKNwwyaPSVYNSRVSSVLPSPHDiPRPKNVYF..SNGVDsEPTYGPTQKMdFELEMGY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.80|      16|      21|     530|     549|       7
---------------------------------------------------------------------------
  530-  549 (19.70/26.64)	EQEDGIENvktGlRRKLFED
  554-  569 (28.10/19.65)	EEEDAEEK...G.NEKMDED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.91|      19|      21|     487|     505|      11
---------------------------------------------------------------------------
  487-  505 (35.28/26.94)	NGDVSK.LNMDDLRDLWDYA
  510-  529 (28.63/20.42)	NGIVREmLENDAFGSLFTMA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP14047 with Med8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NVKTGLRRKLFEDDSDEEEEDAEEKGNEKMDEDRLPEKLAPPPEPGVDPSLPPMRLETVLRFITTGAMPPQR
537
608










Molecular Recognition Features






MoRF SequenceStartStop




1) KMDEDRLPEKLA
2) SLPPMRLETVLRFITTGAMP
565
586
576
605